Antimicrobial susceptibility pattern of bacterial isolates in patients of chronic suppurative otitis media in a tertiary care hospital in India

Background: Chronic suppurative otitis media (CSOM) is a massive public health problem in developing countries like India, especially among low socio-economic class because of malnutrition, overcrowding, poor hygiene, inadequate health care and recurrent upper respiratory tract infections. CSOM cases unless managed effectively may land into various complications such as persistent otorrhoea, hearing impairment, mastoiditis, labyrinthitis, facial nerve paralysis to more serious intracranial abscesses.Methods: The study was carried out in a tertiary care hospital from January 2017 to December 2017 with an aim to determine the microbiological profile of ear discharge in patients suffering from CSOM and their antimicrobial susceptibility pattern using Kirby Bauer disc diffusion method.Results: Out of 630 samples processed, 407 (64.6%) samples were culture positive. Most common organism isolated was Pseudomonas spp. (43.2%) followed by S. aureus (39.1%). Most of isolates recovered were multidrug resistant.Conclusions: Management of CSOM consists mainly of eradicating infection and closure of tympanic membrane. Periodic monitoring of bacterial isolates and their antibiotic susceptibility pattern is necessary for administering appropriate antibiotics as empirical treatment and also helps in reducing the potentially disabling and fatal complications of CSOM.

Download Full-text

Antimicrobial Susceptibility Pattern in Chronic Suppurative Otitis Media Patient in a Tertiary Care Hospital

Value in Health ◽

10.1016/j.jval.2016.08.507 ◽

2016 ◽

Vol 19 (7) ◽

pp. A845-A846 ◽

Cited By ~ 2

Author(s):

A Kumar ◽

L Jayachandran ◽

S Kumar ◽

B R ◽

S A

Keyword(s):

Otitis Media ◽

Antimicrobial Susceptibility ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Chronic Suppurative Otitis Media ◽

Care Hospital ◽

Susceptibility Pattern ◽

Suppurative Otitis Media ◽

Antimicrobial Susceptibility Pattern

Download Full-text

Bacterial Profile and Antimicrobial Susceptibility Pattern of Chronic Suppurative Otitis Media from a Tertiary Care Hospital in Kannauj, Uttar Pradesh, India

JOURNAL FOR CLINICAL AND DIAGNOSTIC RESEARCH ◽

10.7860/jcdr/2021/48334.14770 ◽

2021 ◽

Author(s):

Kiran Yadav ◽

Sandeep Kaushik ◽

Kumkum Rani ◽

Anuj Kumar Tyagi

Keyword(s):

Otitis Media ◽

Antimicrobial Susceptibility ◽

Tertiary Care ◽

Uttar Pradesh ◽

Tympanic Membrane Perforation ◽

Chronic Suppurative Otitis Media ◽

Care Hospital ◽

Susceptibility Pattern ◽

Suppurative Otitis Media ◽

Antimicrobial Susceptibility Pattern

Introduction: Chronic Suppurative Otitis Media (CSOM) is a chronic and persistent inflammation of the mucosal lining of middle ear cleft which presents with recurrent ear discharge through a tympanic membrane perforation. CSOM is a worldwide disease and has higher prevalence in developing countries causing serious local damage and threatening complications. Aim: To determine the profile of CSOM, its causative agents and their antibiotic susceptibility pattern. Materials and Methods: The present study was a retrospective study in which data for culture and antimicrobial susceptibility profile of CSOM cases was retrieved from Microbiology department of Government Medical College, Kannauj, Uttar Pradesh, India, from January 2019 to October 2019 the analysis of data was done in February 2020. Two hundred pus swabs from discharging ears were processed during the study period for aerobic bacterial culture and antimicrobial susceptibility pattern in Microbiology department using standard microbiological techniques. The result analysis of the study was expressed as percentage and proportion for distribution of CSOM cases. Results: Out of 200 patients, 114 (57%) were males and 86 (43%) females. Among the 200 cases, 147 (73.5%) cases showed growth and 53 (26.5%) showed no growth. The most common organism isolated in this study was Pseudomonas aeruginosa, 67 (42.40%) followed by Staphylococcus aureus.48 (30.37%) and Klebsiella spp. 23 (14.55%). Gentamicin (85%) and amikacin (83%) had high level of antibacterial activity on all the isolates. Meropenem was found to be most effective drug for gram negative isolates. All Staphylococcus spp isolates were sensitive to vancomycin (100%). Conclusion:Pseudomonas aeruginosa was the most predominant organism isolated in otitis media patients. Most of the isolates were sensitive to meropenem.

Download Full-text

Bacteriological profile and their antibiotic susceptibility pattern in chronic suppurative otitis media (TTD) in a tertiary care hospital

International Journal of Otorhinolaryngology and Head and Neck Surgery ◽

10.18203/issn.2454-5929.ijohns20192137 ◽

2019 ◽

Vol 5 (4) ◽

pp. 871

Author(s):

Sriram Govindaraj ◽

Jinu Vadakkanethu Iype ◽

Srinivasa V. ◽

Jayendiran S.

Keyword(s):

Otitis Media ◽

Antimicrobial Susceptibility ◽

Antibiotic Susceptibility ◽

Chronic Suppurative Otitis Media ◽

Care Hospital ◽

Bacterial Isolates ◽

Susceptibility Pattern ◽

Suppurative Otitis Media ◽

Antimicrobial Susceptibility Pattern ◽

The Common

Background: Chronic suppurative otitis media (CSOM) is one of the common infective conditions which can cause many complications if not treated properly. Improper use of antibiotic among the common population has led to many drug resistant organisms; therefore it is necessary to study the antimicrobial susceptibility pattern before treating the patient with CSOM. Aim of the study was to identify the bacterial isolates causing CSOM in tubo tympanic disease and to study their antimicrobial susceptibility pattern.Methods: The study was carried out in ENT department in Vinayaka Mission Medical College, Karaikal from July 2018 till December 2018 for six months. 60 patients of CSOM (TTD) with ear discharge attending the ENT Out Patient Department were included in the study. Swabs were collected for culture and sensitivity. Bacterial isolates were identified using standard methods and antibiotic susceptibility testing were done. Results: Pseudomonas species was the most predominant organism, which was seen in 19 patients (38%) followed by Escherichia coli (22%), Staphylococcus aureus (18%), Klebsiella species (10%).Conclusions: A continuous and periodic evaluation of microbiological pattern and their antibiotic sensitivity pattern prevalent in local area, helps in prescribe proper antibiotics for successful treatment of CSOM and thus minimizing its complications and emergence of resistant strains.

Download Full-text