Modafinil: Is it ready for prime time?

2006 ◽  
Vol 2 (3) ◽  
pp. 130 ◽  
Author(s):  
Eric Prommer, MD

Psychostimulants have been used to treat many symptoms associated with advanced cancer. The primary role of psychostimulants in such cases is the treatment of symptoms such as cancer-related fatigue, opioid-induced sedation, depression, and cognitive dysfunction associated with malignancies. These uses for psychostimulants came after approval for treatment of disorders such as attention deficit disorder. Modafinil, a new psychostimulant, is following a similar path after its approval for use in attention deficit disorder in 1998. Modafinil has been used to treat fatigue associated with neurodegenerative disorders such as multiple sclerosis and amyotrophic lateral sclerosis. It is now being increasingly used for cancerrelated symptoms targeted by psychostimulants. Preliminary evidence from literature review suggests that modafinil is efficacious in improving opioid-induced sedation, cancer-related fatigue, and depression. There is no evidence to support its use in the treatment of cognitive dysfunction related to cancer or to support its having analgesic properties. Well-designed, randomized, controlled clinical trials are still needed to further elucidate the precise role of this drug in the care of patients with cancer. Specifically, large placebo-controlled trials with modafinil must be conducted in patients with cancer, with specific attention paid to pain control, depression, cognitive function, and adverse effects.

Author(s):  
Baruch Spivak ◽  
Roni Ioran ◽  
Hana Bar-Iosef ◽  
Graciela Peres ◽  
Roberto Mester ◽  
...  

1997 ◽  
Vol 21 (7) ◽  
pp. 398-400 ◽  
Author(s):  
Kapil Sayal ◽  
Eric Taylor

The strong recent public interest in attention deficit disorder and its drug treatment has led to the need for, and development of, guidelines for clinical practice. As a first step in this process our aim was to ascertain the current level of professional consensus on certain points regarding the use of medication in attention deficit disorder. Although a high level of consensus was found in relation to indications and prescribing issues, opinion was divided on details of how the treatment should be delivered – including the role of paediatricians, and the use of psychological treatments.


1991 ◽  
Vol 16 (2) ◽  
pp. 229-239 ◽  
Author(s):  
Ronald E. Dahl ◽  
William E. Pelham ◽  
Michelle Wierson

1987 ◽  
Vol 32 (5) ◽  
pp. 384-386 ◽  
Author(s):  
William M. Heffron ◽  
Catherine A. Martin ◽  
Richard J. Welsh ◽  
Peggy Perry ◽  
Catherine Kirby Moore

The role of a child in his/her physical abuse was reviewed with particular attention to hyperactive children. A retrospective analysis of the records of children referred to a university-based hyperactive children's clinic revealed that children both with and without Attention Deficit Disorder (ADD) were more often physically abused than children in the general population. The period prevalence of physical abuse in children with ADD did not differ significantly from that in children without ADD. This suggests that hyperactivity may either contribute to, or result from, physical abuse.


Author(s):  
Анна Александровна Васильева

Актуализируется проблема профессионального выгорания педагогов-психологов, обучающих детей с синдромом дефицита внимания, подчеркивается важная роль профилактики профессионального выгорания, рассматриваются разные уровни профессионального выгорания. Приводятся некоторые приемы и методы организации работы, позволяющие оптимизировать процесс обучения и воспитания. Highlights the problem of professional burnout of teachers-psychologists teaching children with attention deficit disorder, emphasizes the important role of prevention of professional burnout, and considers different levels of professional burnout. Some techniques and methods of work organization that allow to optimize the process of training and education are given.


Sign in / Sign up

Export Citation Format

Share Document