Evaluation of treatment changes following electronic consultation to a pharmacist-run urine drug testing service in a veterans healthcare system

2016 ◽  
Vol 12 (6) ◽  
pp. 389 ◽  
Author(s):  
Michelle M. Stammet, PharmD ◽  
Shelley S. Spradley, PharmD, BCPS

In 2013, the North Florida/South Georgia Veterans Healthcare System established a pharmacist-run urine drug testing (UDT) electronic consultation (e-consult) service to assist providers with interpretation of this useful yet complex clinical tool. This pilot study aimed to classify clinical treatment changes implemented following e-consult to a pharmacist-run UDT service and analyze factors limiting pharmacist intervention postconsultation. One hundred forty-three e-consults were completed in the 2-year study period including interpretation of 190 UDT results classified as expected, unexpected, or not necessarily inappropriate based on prescription profile at time of urine immunoassay test. Preconsult evaluation revealed that in more than 70 percent of cases, no confirmatory testing was ordered on the sample in question by the requesting provider. Of the 28 percent of UDT results classified as unexpected, 32 percent identified the presence of an illicit substance. Completed e-consults provided either education-based (informative) or actionbased (decisive) recommendations. In 50 percent of the cases where unexpected substances were identified, pharmacy specialists recommended immediate action to be taken by the provider. Subsequent review indicates that timely documentation of postconsultation action by requesting provider was only present in 32 percent of this group. Continued efforts toward an improved understanding of UDT utility by providers, along with expedited placement of e-consult following urine collection, may allow for increased implementation of pharmacist interventions and lead to more optimal use of this clinical tool.

2015 ◽  
Vol 11 (1) ◽  
Author(s):  
Amadeo Pesce, PhD ◽  
Kenneth L. Kirsh, PhD ◽  
Angela Huskey, PharmD, CPE ◽  
Steven D. Passik, PhD ◽  
Catherine A. Hammett-Stabler, PhD

Objective: To describe the differences between mass spectrometry technologies and compare and contrast them with immunoassay techniques of urine drug testing (UDT). Highlight the potential importance of the differences among these technologies for clinicians so as to allow them make decisions in their use in patient care.Methods: Review of mass spectrometry techniques, including gas chromatography, liquid chromatography, and time-of-flight techniques.Results: The potential clinical implications of these technologies stemming from their scope and accuracy are presented.Significance: UDT is an important clinical tool, though there are differences in technology and testing processes with important implications for clinical decision making. It is crucial, therefore, that clinicians have an understanding of the technologies behind the tests they order, so that their interpretation and use of results are based on an understanding of the strengths and weaknesses of the technologies used.


2021 ◽  
Vol 25 (2) ◽  
Author(s):  
Krishnan Chakravarthy ◽  
Aneesh Goel ◽  
George M. Jeha ◽  
Alan David Kaye ◽  
Paul J. Christo

1988 ◽  
Vol 34 (3) ◽  
pp. 471-473 ◽  
Author(s):  
M A Peat

Abstract Many laboratories are now performing urine drug testing for employers, governmental agencies, and other institutions. It is now recognized that presumptive positive screening results have to be confirmed by an analytical procedure based on a different chemical technique with greater than or equal sensitivity to the screening test. Thin-layer chromatography has been widely used for this; however, it is relatively insensitive for certain drugs, and it cannot satisfy the accuracy and precision requirements needed to determine threshold concentrations reliably. Gas chromatography-mass spectrometry is able to satisfy these threshold requirements and has become the method of choice for confirming initial immunoassay results.


2017 ◽  
Vol 52 (8) ◽  
pp. 497-506 ◽  
Author(s):  
N. N. Stephanson ◽  
P. Signell ◽  
A. Helander ◽  
O. Beck

2008 ◽  
Vol 43 (3-4) ◽  
pp. 513-520 ◽  
Author(s):  
Nouzar Nakhaee ◽  
Kouros Divsalar ◽  
Manzume Shamsi Meimandi ◽  
Shahriar Dabiri

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