Urine interleukin-6, interleukin-8 and transforming growth factor β1 in infants with urinary tract infection and asymptomatic bacteriuria

Implementation of an antimicrobial stewardship program bundle for urinary tract infections among 92 patients led to a higher rate of discontinuation of therapy for asymptomatic bacteriuria (52.4% vs 12.5%; P =.004), more appropriate durations of therapy (88.7% vs 63.6%; P =.001), and significantly higher overall bundle compliance (75% vs 38.2%; P < .001).Infect Control Hosp Epidemiol 2016;1499–1501

Download Full-text

Diagnosis of Urinary Tract Infection in the Neuropathic Bladder: Changing the Paradigm to Include the Microbiome

Topics in Spinal Cord Injury Rehabilitation ◽

10.1310/sci2503-222 ◽

2019 ◽

Vol 25 (3) ◽

pp. 222-227 ◽

Cited By ~ 1

Author(s):

Catherine S. Forster ◽

Hans Pohl

Keyword(s):

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Clinical Management ◽

Significant Variation ◽

Asymptomatic Bacteriuria ◽

Specific Term ◽

Variation In Care ◽

Urinary Microbiome ◽

Definition Of

Bacteriuria, a non-specific term that refers to the presence of bacteria in the urine, is common in people with neuropathic bladders. However, accurately determining when bacteriuria represents a urinary tract infection (UTI) as opposed to asymptomatic bacteriuria is difficult. There is currently no widely accepted definition of what constitutes a UTI in people with neuropathic bladders. As a result, there is significant variation in care, which likely leads to unnecessary use of antibiotics for bacteriuria. To improve the clinical management of people with neuropathic bladders, it is important to be able to accurately diagnose and treat UTIs. In this article, we review the difficulties associated with accurately diagnosing UTIs and then review proposed definitions. Finally, we discuss the emerging literature of the urinary microbiome and how this may assist in accurately diagnosing UTIs in people with neuropathic bladders.

Download Full-text

Asymptomatic Bacteriuria and Urinary Tract Infection in Older Adults

Clinics in Geriatric Medicine ◽

10.1016/j.cger.2007.03.001 ◽

2007 ◽

Vol 23 (3) ◽

pp. 585-594 ◽

Cited By ~ 52

Author(s):

Manisha Juthani-Mehta

Keyword(s):

Older Adults ◽

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Asymptomatic Bacteriuria

Download Full-text

Fever

Acute Care Casebook ◽

10.1093/med/9780190865412.003.0044 ◽

2018 ◽

pp. 217-220

Author(s):

Glenn Patriquin

Keyword(s):

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Asymptomatic Bacteriuria ◽

Common Causes ◽

Criteria For Diagnosis ◽

Tract Infections ◽

Healthcare Associated ◽

Specific Symptoms ◽

Growth Of Bacteria

This case illustrates one of the most common healthcare-associated infections (HAI) in a patient who is admitted to hospital. Catheter-associated urinary tract infections (CAUTI) can be prevented by eliminating unnecessary urinary catheter use. Furthermore, non-specific symptoms are frequently erroneously attributed to a presumed urinary tract infection (UTI) upon isolating bacteria from a urine sample. Except for a few specific circumstances, asymptomatic bacteriuria should not be treated with antibiotics. Without symptoms consistent with UTI, growth of bacteria from urine does not constitute an infection. Culturing urine without UTI symptoms can lead to misuse of antibiotics, which can increase adverse events and drive antimicrobial resistance. This case reviews common causes of UTIs and criteria for diagnosis.

Download Full-text