scholarly journals Erectile function in SRY positive 46,XX males with normal phenotype

2021 ◽  
Vol 74 ◽  
Genetics ◽  
2003 ◽  
Vol 163 (1) ◽  
pp. 245-251 ◽  
Author(s):  
Indrajit Nanda ◽  
Ute Hornung ◽  
Mariko Kondo ◽  
Michael Schmid ◽  
Manfred Schartl

Abstract In the medaka, a duplicated version of the dmrt1 gene, dmrt1bY, has been identified as a candidate for the master male sex-determining gene on the Y chromosome. By screening several strains of Northern and Southern medaka we identified a considerable number of males with normal phenotype and uncompromised fertility, but lacking dmrt1bY. The frequency of such males was >10% in some strains and zero in others. Analysis for the presence of other Y-linked markers by FISH analysis, PCR, and phenotype indicated that their genotype is XX. Crossing such males with XX females led to a strong female bias in the offspring and also to a reappearance of XX males in the following generations. This indicated that the candidate male sex-determining gene dmrt1bY may not be necessary for male development in every case, but that its function can be taken over by so far unidentified autosomal modifiers.


2007 ◽  
Vol 177 (4S) ◽  
pp. 264-265
Author(s):  
Ling De Young ◽  
KokBin Lim ◽  
Jeffery Carson ◽  
Trustin Domes ◽  
Mussa Al-Numi ◽  
...  

2007 ◽  
Vol 177 (4S) ◽  
pp. 386-387
Author(s):  
Andreas Bannowsky ◽  
Heiko Schulze ◽  
Christof van der Horst ◽  
Stefan Hautmann ◽  
Klaus P. Juenemann

2005 ◽  
Vol 173 (4S) ◽  
pp. 78-79 ◽  
Author(s):  
David Burday ◽  
Tim Weber ◽  
Scott Thurman ◽  
Rafael E. Carrion ◽  
Jorge Lockhart
Keyword(s):  

2005 ◽  
Vol 173 (4S) ◽  
pp. 91-91 ◽  
Author(s):  
Jennifer Tash Anger ◽  
Neil D. Sherman ◽  
George D. Webster
Keyword(s):  

2004 ◽  
Vol 171 (4S) ◽  
pp. 373-373
Author(s):  
Trinity J. Bivalacqua ◽  
Mustafa F. Usta ◽  
Hunter C. Champion ◽  
Weiwen Deng ◽  
Philip J. Kadowitz ◽  
...  

2004 ◽  
Vol 171 (4S) ◽  
pp. 177-177 ◽  
Author(s):  
Scott Thurman ◽  
Raviender Bukkapatnam ◽  
Mayer Fishman ◽  
John D. Seigne ◽  
Raoul Salup ◽  
...  

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