The consortium GLADSOILMAP

Author(s):  
Dominique Arrouays ◽  
Zamir Libohova ◽  
Budiman Minansny ◽  
Vera Leatitia Mulder ◽  
Laura Poggio ◽  
...  

<p>Soils have critical relevance to global issues, such as food and water security, climate regulation, sustainable energy, desertification and biodiversity protection. All these examples require accurate national soil property information and there is a need to scientific support to develop reliable baseline soil information and pathways for measuring and monitoring soils. Soil sustainable management is a global issue, but effective actions require high-resolution data about soil properties. Two projects, GlobalSoilMap and SoilGrids, aim at delivering the first generation of high-resolution soil property grids for the globe, the first one by a bottom-up approach (from country to globe), the latter by top-down (global). The GLobAl Digital SOIL MAP (GLADSOILMAP) consortium brings together world scientific leaders involved in both projects. The consortium aims at developing and transferring methods to improve the prediction accuracy of soil properties and their associated uncertainty, by using legacy soil data and ancillary spatial information. This approach brings together new technologies and methods, existing soil databases and expert knowledge. The consortium aims at transferring methods to achieve convergence between top-down and bottom-up approaches, and to generate methods for delivering maps of soil properties. These maps are essential for communities from climate and environmental modeling to decision making and sustainable resources management at a scale that is relevant to soil management. The consortium will ensure links with the numerous actors in geosciences of the world, and will contribute to improving their skills in digital mapping and their national and international legibility. The actions include 4 main Work Packages (WP) subdivided into several tasks that are summarized below:</p><p> </p><p>WP0 Management of the project</p><p>WP1 Legacy and ancillary data for Digital Soil Mapping (DSM)</p><p>Test the potential of new ancillary data for DSM</p><p>Explore methodologies to merge and/or harmonize different products</p><p>Propose methods for harmonizing products to a common date</p><p> </p><p>WP2 Methods for sampling, modelling and mapping soils in space and time</p><p>Testing and developing new methods/models for prediction</p><p>Testing methods for estimating complete probability distribution</p><p> </p><p>WP3 Methods for estimating model and map uncertainty</p><p>Develop methods of uncertainty spatial assessment</p><p>Develop methods do deal with censored data/soft data</p><p>Solve the question of influence on the age of the rescued soil data on predictions</p><p> </p><p>WP4 Scientific outreach and capacity building</p><p>Produce an exhaustive review of GlobalSoilMap initiatives and results all over the world</p><p>Revise and update the GlobalSoilMap specifications by keeping them at the state-of-the-art level</p><p>Show relevance of gridded, Global, DSM by use cases and communication to end users</p><p> </p><p>The added value of the consortium is to allow a direct scientific exchange between members that should result in synthesis papers, in the identification of the major knowledge gaps, and in extending, deepening and disseminating knowledge of DSM, with the final aim to contribute to the achievement of global soil maps. Another added value of the consortium will certainly be to foster the creation of new ideas.</p><p> </p><p>Acknowledgements: the Consortium GLADSOILMAP is supported by LE STUDIUM Loire Valley Institute for Advanced studies.</p>

Cities ◽  
2018 ◽  
Vol 72 ◽  
pp. 287-294 ◽  
Author(s):  
Stefan Lüthi ◽  
Alain Thierstein ◽  
Michael Hoyler

PROTEOMICS ◽  
2017 ◽  
Vol 17 (23-24) ◽  
pp. 1600321 ◽  
Author(s):  
Kira Vyatkina ◽  
Lennard J. M. Dekker ◽  
Si Wu ◽  
Martijn M. VanDuijn ◽  
Xiaowen Liu ◽  
...  

2012 ◽  
Vol 8 (3) ◽  
Author(s):  
Laura Hosman ◽  
Elizabeth Fife

The African continent currently boasts the highest mobile telephony growth rates in the world, bringing new communications possibilities to millions of people. The potential for mobile phones to reach a large and growing base of users across the continent, and be used for development-related purposes, is becoming widely recognized, evidenced by the growing number of development-oriented projects, applications, and programs that specifically make use of mobiles. Pent up demand and limited resources have led to innovative usage and services being developed at the grassroots level. Yet much remains to be done by governments in order to support further growth of telecommunications markets and services, while the private sector, non-profits, and academics all have an important role to play in the development process as well. The phenomenon of top-down-meeting-bottom up partnerships that are springing up across the continent offers the potential for cultivating the necessary feedback loops between various actors involved in the development process, in order to create relevant applications that meet real needs.


Author(s):  
Sukjae Lee

This paper argues that Berkeley restricts his endorsement of the continuous creation thesis to the domain of physical bodies. Such a restricted application of the thesis reveals the distinctive nature of Berkeley’s occasionalism, an occasionalism ‘contained’. In contrast to the ‘top-down’ approach of Malebranche, where foundational theological principles dictate the nature of divine and creaturely causality, resulting in a type of global occasionalism, in the case of Berkeley, the approach is better characterized as one that is ‘bottom up’, an occasionalism that finds its place after the basic setup of the metaphysical makeup of the world is in place. Consistent with this reading is the suggestion that Berkeley’s occasionalism thus restricted is motivated by the explanatory advantages of occasionalism rather than the theological claim that conservation is continuous creation.


2013 ◽  
Author(s):  
Peter Trefonas ◽  
James W. Thackeray ◽  
Guorong Sun ◽  
Sangho Cho ◽  
Corrie Clark ◽  
...  

Author(s):  
Theresa Hitchens

Governance of the use of space, both at the national and the international level, is complicated. Because most countries in the world have been reticent over the last thirty years to negotiate new legally binding commitments in space, ongoing multilateral work on space governance has concentrated primarily on voluntary measures. This chapter reviews and compares the two most salient of these initiatives: the normative recommendations of the UN Group of Governmental Experts (GGE) and the Guidelines for the Long-Term Sustainability of Outer Space Activities agreed by the Committee on the Peaceful Uses of Outer Space Working Group. While the GGE was “top-down” focused on transparency and confidence-building to avoid conflict among States, the LTS Working Group was a “bottom-up” approach for safe and sustainable practices with regard to the use of space. The conclusion looks at how States can best implement the recommendations.


2013 ◽  
Vol 12 (4) ◽  
pp. 043006 ◽  
Author(s):  
Peter Trefonas ◽  
James W. Thackeray ◽  
Guorong Sun ◽  
Sangho Cho ◽  
Corrie Clark ◽  
...  

2020 ◽  
Vol 58 (6) ◽  
pp. 864-872
Author(s):  
Kendall W. Cradic ◽  
Paula M. Ladwig ◽  
Ann L. Rivard ◽  
Waddah Katrangi ◽  
Karl Florian Wintgens ◽  
...  

AbstractBackgroundWhile quantitation methods for small-molecule and tryptic peptide bottom-up mass spectrometry (MS) have been well defined, quantitation methods for top-down or middle-up MS approaches have not been as well defined. Therapeutic monoclonal antibodies (t-mAbs) are a group of proteins that can be used to both demonstrate the advantages of top-down or middle-up detection methods over classic tryptic peptide bottom-up along with the growing need for robust quantitation strategies/software for these top-down or middle-up methods. Bottom-up proteolytic digest methods for the t-mAbs tend to suffer from challenges such as limited peptide selection due to potential interference from the polyclonal immunoglobulin background, complicated workflows, and inadequate sensitivity and specificity without laborious purification steps, and therefore have prompted the search for new detection and quantitation methods. Time-of-flight along with Orbitrap MS have recently evolved from the research and/or pharmaceutical setting into the clinical laboratory. With their superior mass measurement accuracy, resolution and scanning speeds, these are ideal platforms for top-down or middle-up characterization and quantitation.MethodsWe demonstrate a validated, robust, middle-up protein subunit detection and quantitation method for the IgG1 t-mAb, vedolizumab (VEDO), which takes advantage of the high resolution of the Orbitrap MS detection and quantitation software to increase specificity.ResultsValidated performance characteristics met pre-defined acceptance criteria with simple workflows and rapid turnaround times: characteristics necessary for implementation into a high-volume clinical MS laboratory.ConclusionsWhile the extraction method can easily be used with other IgG1 t-mAbs, the detection and quantitation method may become an option for measurement of other proteins.


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