Company Mention Detection for Large Scale Text Mining

Author(s):  
Rebecca J. Passonneau ◽  
Tifara Ramelson ◽  
Boyi Xie
Keyword(s):  
2020 ◽  
Author(s):  
Amir Karami ◽  
Brandon Bookstaver ◽  
Melissa Nolan

BACKGROUND The COVID-19 pandemic has impacted nearly all aspects of life and has posed significant threats to international health and the economy. Given the rapidly unfolding nature of the current pandemic, there is an urgent need to streamline literature synthesis of the growing scientific research to elucidate targeted solutions. While traditional systematic literature review studies provide valuable insights, these studies have restrictions, including analyzing a limited number of papers, having various biases, being time-consuming and labor-intensive, focusing on a few topics, incapable of trend analysis, and lack of data-driven tools. OBJECTIVE This study fills the mentioned restrictions in the literature and practice by analyzing two biomedical concepts, clinical manifestations of disease and therapeutic chemical compounds, with text mining methods in a corpus containing COVID-19 research papers and find associations between the two biomedical concepts. METHODS This research has collected papers representing COVID-19 pre-prints and peer-reviewed research published in 2020. We used frequency analysis to find highly frequent manifestations and therapeutic chemicals, representing the importance of the two biomedical concepts. This study also applied topic modeling to find the relationship between the two biomedical concepts. RESULTS We analyzed 9,298 research papers published through May 5, 2020 and found 3,645 disease-related and 2,434 chemical-related articles. The most frequent clinical manifestations of disease terminology included COVID-19, SARS, cancer, pneumonia, fever, and cough. The most frequent chemical-related terminology included Lopinavir, Ritonavir, Oxygen, Chloroquine, Remdesivir, and water. Topic modeling provided 25 categories showing relationships between our two overarching categories. These categories represent statistically significant associations between multiple aspects of each category, some connections of which were novel and not previously identified by the scientific community. CONCLUSIONS Appreciation of this context is vital due to the lack of a systematic large-scale literature review survey and the importance of fast literature review during the current COVID-19 pandemic for developing treatments. This study is beneficial to researchers for obtaining a macro-level picture of literature, to educators for knowing the scope of literature, to journals for exploring most discussed disease symptoms and pharmaceutical targets, and to policymakers and funding agencies for creating scientific strategic plans regarding COVID-19.


2017 ◽  
Vol 139 (11) ◽  
Author(s):  
Feng Shi ◽  
Liuqing Chen ◽  
Ji Han ◽  
Peter Childs

With the advent of the big-data era, massive information stored in electronic and digital forms on the internet become valuable resources for knowledge discovery in engineering design. Traditional document retrieval method based on document indexing focuses on retrieving individual documents related to the query, but is incapable of discovering the various associations between individual knowledge concepts. Ontology-based technologies, which can extract the inherent relationships between concepts by using advanced text mining tools, can be applied to improve design information retrieval in the large-scale unstructured textual data environment. However, few of the public available ontology database stands on a design and engineering perspective to establish the relations between knowledge concepts. This paper develops a “WordNet” focusing on design and engineering associations by integrating the text mining approaches to construct an unsupervised learning ontology network. Subsequent probability and velocity network analysis are applied with different statistical behaviors to evaluate the correlation degree between concepts for design information retrieval. The validation results show that the probability and velocity analysis on our constructed ontology network can help recognize the high related complex design and engineering associations between elements. Finally, an engineering design case study demonstrates the use of our constructed semantic network in real-world project for design relations retrieval.


Author(s):  
Patrice Bellot ◽  
Ludovic Bonnefoy ◽  
Vincent Bouvier ◽  
Frédéric Duvert ◽  
Young-Min Kim

2017 ◽  
Author(s):  
Morgan N. Price ◽  
Adam P. Arkin

AbstractLarge-scale genome sequencing has identified millions of protein-coding genes whose function is unknown. Many of these proteins are similar to characterized proteins from other organisms, but much of this information is missing from annotation databases and is hidden in the scientific literature. To make this information accessible, PaperBLAST uses EuropePMC to search the full text of scientific articles for references to genes. PaperBLAST also takes advantage of curated resources that link protein sequences to scientific articles (Swiss-Prot, GeneRIF, and EcoCyc). PaperBLAST’s database includes over 700,000 scientific articles that mention over 400,000 different proteins. Given a protein of interest, PaperBLAST quickly finds similar proteins that are discussed in the literature and presents snippets of text from relevant articles or from the curators. PaperBLAST is available at http://papers.genomics.lbl.gov/.


2019 ◽  
Vol 12 (S8) ◽  
Author(s):  
Yanhuang Jiang ◽  
Chengkun Wu ◽  
Yanghui Zhang ◽  
Shaowei Zhang ◽  
Shuojun Yu ◽  
...  

Abstract Background An important task in the interpretation of sequencing data is to highlight pathogenic genes (or detrimental variants) in the field of Mendelian diseases. It is still challenging despite the recent rapid development of genomics and bioinformatics. A typical interpretation workflow includes annotation, filtration, manual inspection and literature review. Those steps are time-consuming and error-prone in the absence of systematic support. Therefore, we developed GTX.Digest.VCF, an online DNA sequencing interpretation system, which prioritizes genes and variants for novel disease-gene relation discovery and integrates text mining results to provide literature evidence for the discovery. Its phenotype-driven ranking and biological data mining approach significantly speed up the whole interpretation process. Results The GTX.Digest.VCF system is freely available as a web portal at http://vcf.gtxlab.com for academic research. Evaluation on the DDD project dataset demonstrates an accuracy of 77% (235 out of 305 cases) for top-50 genes and an accuracy of 41.6% (127 out of 305 cases) for top-5 genes. Conclusions GTX.Digest.VCF provides an intelligent web portal for genomics data interpretation via the integration of bioinformatics tools, distributed parallel computing, biomedical text mining. It can facilitate the application of genomic analytics in clinical research and practices.


2011 ◽  
Vol 12 (1) ◽  
Author(s):  
Paul Thompson ◽  
John McNaught ◽  
Simonetta Montemagni ◽  
Nicoletta Calzolari ◽  
Riccardo del Gratta ◽  
...  

2020 ◽  
Author(s):  
Debarati Roychowdhury ◽  
Samir Gupta ◽  
Xihan Qin ◽  
Cecilia N. Arighi ◽  
K. Vijay-Shanker

AbstractMotivationmicroRNAs (miRNAs) are essential gene regulators and their dysregulation often leads to diseases. Easy access to miRNA information is crucial for interpreting generated experimental data, connecting facts across publications, and developing new hypotheses built on previous knowledge. Here, we present emiRIT, a text mining-based resource, which presents miRNA information mined from the literature through a user-friendly interface.ResultsWe collected 149,233 miRNA-PubMed ID pairs from Medline between January 1997 to May 2020. emiRIT currently contains miRNA-gene regulation (60,491 relations); miRNA-disease (cancer) (12,300 relations); miRNA-biological process and pathways (23,390 relations); and circulatory miRNAs in extracellular locations (3,782 relations). Biological entities and their relation to miRNAs were extracted from Medline abstracts using publicly available and in-house developed text mining tools, and the entities were normalized to facilitate querying and integration. We built a database and an interface to store and access the integrated data, respectively.ConclusionWe provide an up-to-date and user-friendly resource to facilitate access to comprehensive miRNA information from the literature on a large-scale, enabling users to navigate through different roles of miRNA and examine them in a context specific to their information needs. To assess our resource’s information coverage, in the absence of gold standards, we have conducted two case studies focusing on the target and differential expression information of miRNAs in the context of diseases. Database URL: https://research.bioinformatics.udel.edu/emirit/


Land ◽  
2020 ◽  
Vol 9 (9) ◽  
pp. 287 ◽  
Author(s):  
Jae-hyuck Lee ◽  
Do-kyun Kim

Mapping the characteristics and extent of environmental conflicts related to land use is important for developing regionally specific policies. However, because it is only possible to verify the frequency of conflicts on a specific predetermined subject, it is difficult to determine the various reasons for conflicts in a region. Therefore, this study mapped the current status of regional environmental conflicts in South Korea using a spatial text mining technique, then proposed relevant management policies. The results were obtained by analyzing environmental conflict data extracted from the online agendas of regional environmental organizations. Air quality-related conflicts in South Korea are concentrated in western municipalities; development-related conflicts are concentrated in the southern region of Jeju Island; and intensive safety-related conflicts occur in metropolitan areas, particularly Ulsan. Thus, the type of conflict is determined by the local environment, in accordance with the definition of environmental conflict, and the distribution is determined by the location of the stakeholder population. This study reveals the issues and locations related to local environmental conflict that require further attention, and proposes more wide-ranging methods for managing the links between conflicts by mapping environmental conflicts on a large scale rather than on an individual basis.


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