Investigating Diseases and Chemicals in COVID-19 Literature with Text Mining (Preprint)

2020 ◽  
Author(s):  
Amir Karami ◽  
Brandon Bookstaver ◽  
Melissa Nolan
Keyword(s):  
Text Mining ◽  
Literature Review ◽  
Topic Modeling ◽  
Large Scale ◽  
Clinical Manifestations ◽  
International Health ◽  
Research Papers ◽  
Strategic Plans ◽  
Funding Agencies ◽  
The Relationship

BACKGROUND The COVID-19 pandemic has impacted nearly all aspects of life and has posed significant threats to international health and the economy. Given the rapidly unfolding nature of the current pandemic, there is an urgent need to streamline literature synthesis of the growing scientific research to elucidate targeted solutions. While traditional systematic literature review studies provide valuable insights, these studies have restrictions, including analyzing a limited number of papers, having various biases, being time-consuming and labor-intensive, focusing on a few topics, incapable of trend analysis, and lack of data-driven tools. OBJECTIVE This study fills the mentioned restrictions in the literature and practice by analyzing two biomedical concepts, clinical manifestations of disease and therapeutic chemical compounds, with text mining methods in a corpus containing COVID-19 research papers and find associations between the two biomedical concepts. METHODS This research has collected papers representing COVID-19 pre-prints and peer-reviewed research published in 2020. We used frequency analysis to find highly frequent manifestations and therapeutic chemicals, representing the importance of the two biomedical concepts. This study also applied topic modeling to find the relationship between the two biomedical concepts. RESULTS We analyzed 9,298 research papers published through May 5, 2020 and found 3,645 disease-related and 2,434 chemical-related articles. The most frequent clinical manifestations of disease terminology included COVID-19, SARS, cancer, pneumonia, fever, and cough. The most frequent chemical-related terminology included Lopinavir, Ritonavir, Oxygen, Chloroquine, Remdesivir, and water. Topic modeling provided 25 categories showing relationships between our two overarching categories. These categories represent statistically significant associations between multiple aspects of each category, some connections of which were novel and not previously identified by the scientific community. CONCLUSIONS Appreciation of this context is vital due to the lack of a systematic large-scale literature review survey and the importance of fast literature review during the current COVID-19 pandemic for developing treatments. This study is beneficial to researchers for obtaining a macro-level picture of literature, to educators for knowing the scope of literature, to journals for exploring most discussed disease symptoms and pharmaceutical targets, and to policymakers and funding agencies for creating scientific strategic plans regarding COVID-19.

scholarly journals A large-scale validation of the relationship between cross-disciplinary research and its uptake in policy-related documents, using the novel Overton altmetrics database

2021 ◽  
pp. 1-40
Author(s):  
Henrique Pinheiro ◽  
Etienne Vignola-Gagné ◽  
David Campbell
Keyword(s):  
Large Scale ◽  
Scale Validation ◽  
The Novel ◽  
Policy Interactions ◽  
Societal Challenges ◽  
Research Outcomes ◽  
Policy Relevance ◽  
Funding Agencies ◽  
The Relationship ◽  
Disciplinary Diversity

Abstract Cross-disciplinary research (multi-/inter-disciplinarity) is incentivised by funding agencies to foster research outcomes addressing complex societal challenges. This study focuses on the link between crossdisciplinary research and its uptake in a broad set of policy-related documents. Using the new policyoriented database Overton, matched to Scopus, logistic regression was used in assessing this relationship in publications from FP7- and H2020-supported projects. Cross-disciplinary research was captured through two lenses at the paper level, namely from the disciplinary diversity of contributing authors (DDA) and of cited references (DDR). DDA increased the likelihood that publications were cited in policy documents, with DDR possibly making a contribution, but only when publications result from the work of few authors. Citations to publications captured by Overton were found to originate in scientific advice documents, rather than in legislative or executive records. Our approach enables testing in a general way the assumption underlying many funding programmes, namely that cross-disciplinary research will increase the policy relevance of research outcomes. Findings suggest that research assessments could benefit from measuring uptake in policy-related literature, following additional characterisation of the Overton database; of the science-policy interactions it captures; and of the contribution of these interactions within the larger policymaking process. Peer Review https://publons.com/publon/10.1162/qss_a_00137

The Study of Classification Analysis on Oil Exploration Research Trends and Digging Technology Based on Properties of Biochemical Materials (2012-2013)

2013 ◽  
Vol 859 ◽  
pp. 280-283
Author(s):  
Shiang Hau Wu ◽  
Jiann Jong Guo
Keyword(s):  
Text Mining ◽  
Random Forests ◽  
Research Trends ◽  
Oil Exploration ◽  
Mining Method ◽  
Research Papers ◽  
Classification Analysis ◽  
Relationship Of ◽  
The Relationship ◽  
Random Forests Model

The study aimed at analyzing the keywords of the oil exploration research papers abstracts in 2012 and 2013 and using the random forests model to make the classification analysis in order to find the importance and similarities of 2012 and 2013 research trends. The contribution of the study included the following two points. First, the study used the text mining method in order to explore the content of oil exploration research paper abstracts. Second, the study applied the AdaBoost classification analysis to explore the relationship of the keywords between the two years’ keywords.

scholarly journals A Systematic Literature Review of Sexual Harassment Studies with Text Mining

2021 ◽  
Vol 13 (12) ◽  
pp. 6589
Author(s):  
Amir Karami ◽  
Melek Yildiz Spinel ◽  
C. Nicole White ◽  
Kayla Ford ◽  
Suzanne Swan
Keyword(s):  
Text Mining ◽  
Sexual Harassment ◽  
Literature Review ◽  
Trend Analysis ◽  
Temporal Trend ◽  
Temporal Trends ◽  
Research Papers ◽  
Qualitative Approaches ◽  
Research Theme ◽  
Wide Range

Sexual harassment has been the topic of thousands of research articles in the 20th and 21st centuries. Several review papers have been developed to synthesize the literature about sexual harassment. While traditional literature review studies provide valuable insights, these studies have some limitations including analyzing a limited number of papers, being time-consuming and labor-intensive, focusing on a few topics, and lacking temporal trend analysis. To address these limitations, this paper employs both computational and qualitative approaches to identify major research topics, explore temporal trends of sexual harassment topics over the past few decades, and point to future possible directions in sexual harassment studies. We collected 5320 research papers published between 1977 and 2020, identified and analyzed sexual harassment topics, and explored the temporal trend of topics. Our findings indicate that sexual harassment in the workplace was the most popular research theme, and sexual harassment was investigated in a wide range of spaces ranging from school to military settings. Our analysis shows that 62.5% of the topics having a significant trend had an increasing (hot) temporal trend that is expected to be studied more in the coming years. This study offers a bird’s eye view to better understand sexual harassment literature with text mining, qualitative, and temporal trend analysis methods. This research could be beneficial to researchers, educators, publishers, and policymakers by providing a broad overview of the sexual harassment field.

scholarly journals THE CONDITION OF THE PSYCHOEMOTIONAL STATUS IN PATIENTS WITH DIFFUSE TELOGEN HAIR LOSS

2017 ◽  
Vol 20 (5) ◽  
pp. 285-289
Author(s):  
Elena L. Uryupina ◽  
N. P Malishevskaya
Keyword(s):  
Literature Review ◽  
Hair Loss ◽  
Clinical Manifestations ◽  
Personality Type ◽  
Growth Cycle ◽  
Hair Follicles ◽  
Psychological State ◽  
Integrated Analysis ◽  
The Future ◽  
The Relationship

Diffuse telogenetic alopecia is a polyethological disease accompanied by a disruption in the operation of the hair follicles cells and leading, in the future, to the growth cycle failure and development of the hair, which subsequently leads to thinning and excessive hair loss. The results of the study of psychoemotional disorders in patients with telogen hair loss identified by integrated analysis of anamnestic data, patient’s complaints, the survey using validated psychotherapeutic tests and subsequent consultation with a doctor-psychotherapist are presented. The relationship between personality type, psychological state and the severity of clinical manifestations was detected. The dominant triggering factors of development of diffuse alopecia severe forms were determined. The relationship between the severity of clinical manifestations and the position was found. Based on the analysis of the obtained data, literature review and the example of two clinical cases of patients with diffuse telogenous alopecia was shown the importance of identifying correction of alexithymia and depression with the aim of increasing the effectiveness of therapy.

Holistic Approach to Transformational and Transactional Project Leadership Styles: Literature Review 2016–2019

2021 ◽  
pp. 30-41
Author(s):  
Alena Trublovskaya ◽  
Ol'ga Gordienko ◽  
Anna Chigrina ◽  
Artem Abdrahmanov ◽  
Anastasiya Gorodnicheva
Keyword(s):  
Literature Review ◽  
Citation Index ◽  
Holistic Approach ◽  
Future Research ◽  
Research Papers ◽  
Project Leadership ◽  
H Index ◽  
Article Citation ◽  
The Relationship ◽  
Insight Into

The notion of project leadership is considered to be one of the most popular topics among both researchers and managers. However, the question of whether transformational project leadership (TFL) or transactional project leadership (TAL) is more efficient for organizations is widely debated. The aim of this study is to provide an overview of the tendencies in the research of TFL and TAL in 2016–2019. This study was based on literature review and selected research articles of each year from Scopus according to particular metrics: article citation index, author h-index and journal CiteScore. A questionnaire among experts was conducted in order to evaluate the relationship between the metrics. The main contribution of this study is that it unites research papers of a different focus and offers insight into the key findings on the notions of TFL and TAL in the last four years. The study shows that TFL and TAL were found to have both positive and negative implications under certain factors and circumstances. Furthermore, the study indicates that TFL and TAL do not oppose but rather complement each other. Hence, the balance between TFL and TAL is likely to be an optimum choice. Limitations of the study and recommendations for future research are thoroughly discussed in the paper.

scholarly journals Potential Beneficial Effects of Probiotics on Human Migraine Headache: A Literature Review

2017 ◽  
Vol 2 (20;2) ◽  
pp. E251-E255
Author(s):  
Yong-Hai Sun
Keyword(s):  
Literature Review ◽  
Gut Microbiota ◽  
Brain Function ◽  
Migraine Headache ◽  
Large Scale ◽  
Gastrointestinal Diseases ◽  
Gastrointestinal Disorders ◽  
Efficacy And Safety ◽  
Positive Effects ◽  
The Relationship

Background: Recent studies have shown that migraine headache is often associated with concomitant gastrointestinal diseases. There is a higher prevalence of headaches in patients with gastrointestinal disorders. These associations between migraine and gastrointestinal disorders suggest a potential link to a bidirectional modulation of gut microbiota and brain function. The underlying working mechanistic links between migraine and gastrointestinal diseases may include increased intestinal epithelial permeability and inflammation. Objective: This review presents an overview of the relationship between gut microbiota and brain function, especially with regard to migraine headache. Study Design: Literature review. Setting: Anesthesia and Operation Center, Department of Anesthesiology, Chinese PLA General Hospital. Methods: The present investigation included a PubMed search using the following terms: migraine headache, gut microbiota, brain function, and probiotics. Results: In this literature review, we mainly discussed the relationship between gut microbiota and brain function, especially with regard to migraine headache. The potential effects of probiotics supplement on migraine headache were also included. Limitations: There is limited evidence from clinical studies of the positive effects of probiotics in patients with migraine headache. Large-scale randomized, placebo-controlled clinical trials are warranted to evaluate the clinical efficacy and safety of probiotics in patients with migraine headache. Conclusions: Similar to migraine headache, disorders of the brain involving depression and anxiety have been demonstrated to be associated with increased gut permeability. An improvement in gut microbiota and reduction of inflammation can have positive effects on strengthening gut and brain function. Moreover, it can be inferred that probiotics may have a beneficial effect on the frequency and severity of migraine headache attacks. Large-scale randomized, placebo-controlled studies are warranted in the future to evaluate the clinical efficacy and safety of probiotics in patients with migraine headache. Key words: Migraine headache, gut microbiota, brain function, probiotics

scholarly journals Analyzing Empowerment Processes Among Cancer Patients in an Online Community: A Text Mining Approach (Preprint)

2018 ◽  
Author(s):  
Suzan Verberne ◽  
Anika Batenburg ◽  
Remco Sanders ◽  
Mies van Eenbergen ◽  
Enny Das ◽  
...  
Keyword(s):  
Text Mining ◽  
Cancer Patients ◽  
Emotional Support ◽  
Large Scale ◽  
Peer To Peer ◽  
Psychological Processes ◽  
Informational Support ◽  
Online Social Support ◽  
Different Types ◽  
The Relationship

BACKGROUND Peer-to-peer online support groups and the discussion forums in these groups can help patients by providing opportunities for increasing their empowerment. Most previous research on online empowerment and online social support uses qualitative methods or questionnaires to gain insight into the dynamics of online empowerment processes. OBJECTIVE The overall goal of this study was to analyze the presence of the empowerment processes in the online peer-to-peer communication of people affected by cancer, using text mining techniques. Use of these relatively new methods enables us to study social processes such as empowerment on a large scale and with unsolicited data. METHODS The sample consisted of 5534 messages in 1708 threads, written by 2071 users of a forum for cancer patients and their relatives. We labeled the posts in our sample with 2 types of labels: labels referring to empowerment processes and labels denoting psychological processes. The latter were identified using the Linguistic Inquiry and Word Count (LIWC) method. Both groups of labels were automatically assigned to posts. Automatic labeling of the empowerment processes was done by text classifiers trained on a manually labeled subsample. For the automatic labeling of the LIWC categories, we used the Dutch version of the LIWC consisting of a total of 66 word categories that are assigned to text based on occurrences of words in the text. After the automatic labeling with both types of labels, we investigated (1) the relationship between empowerment processes and the intensity of online participation, (2) the relationship between empowerment processes and the LIWC categories, and (3) the differences between patients with different types of cancer. RESULTS The precision of the automatic labeling was 85.6%, which we considered to be sufficient for automatically labeling the complete corpus and doing further analyses on the labeled data. Overall, 62.94% (3482/5532) of the messages contained a narrative, 23.83% (1318/5532) a question, and 27.49% (1521/5532) informational support. Emotional support and references to external sources were less frequent. Users with more posts more often referred to an external source and more often provided informational support and emotional support (Kendall τ>0.2; P<.001) and less often shared narratives (Kendall τ=−0.297; P<.001). A number of LIWC categories are significant predictors for the empowerment processes: words expressing assent (ok and yes) and emotional processes (expressions of feelings) are significant positive predictors for emotional support (P=.002). The differences between patients with different types of cancer are small. CONCLUSIONS Empowerment processes are associated with the intensity of online use. The relationship between linguistic analyses and empowerment processes indicates that empowerment processes can be identified from the occurrences of specific linguistic cues denoting psychological processes.

Relationship between total plasma homocysteine and the risk of aneurysms – a meta-analysis

VASA ◽  
2020 ◽  
pp. 1-6
Author(s):  
Hanji Zhang ◽  
Dexin Yin ◽  
Yue Zhao ◽  
Yezhou Li ◽  
Dejiang Yao ◽  
...  
Keyword(s):  
Large Scale ◽  
Meta Analysis ◽  
Single Species ◽  
Total Plasma ◽  
Control Groups ◽  
Randomized Controlled ◽  
Randomized Controlled Studies ◽  
The Difference ◽  
The Relationship ◽  
Healthy Participants

Summary: Our meta-analysis focused on the relationship between homocysteine (Hcy) level and the incidence of aneurysms and looked at the relationship between smoking, hypertension and aneurysms. A systematic literature search of Pubmed, Web of Science, and Embase databases (up to March 31, 2020) resulted in the identification of 19 studies, including 2,629 aneurysm patients and 6,497 healthy participants. Combined analysis of the included studies showed that number of smoking, hypertension and hyperhomocysteinemia (HHcy) in aneurysm patients was higher than that in the control groups, and the total plasma Hcy level in aneurysm patients was also higher. These findings suggest that smoking, hypertension and HHcy may be risk factors for the development and progression of aneurysms. Although the heterogeneity of meta-analysis was significant, it was found that the heterogeneity might come from the difference between race and disease species through subgroup analysis. Large-scale randomized controlled studies of single species and single disease species are needed in the future to supplement the accuracy of the results.

A literature review on firms' internationalisation through e-commerce

2019 ◽  
pp. 121-143
Author(s):  
Riccardo Resciniti ◽  
Federica De Vanna
Keyword(s):  
Systematic Review ◽  
Literature Review ◽  
International Business ◽  
Decision Process ◽  
Foreign Markets ◽  
New Markets ◽  
Integrative Framework ◽  
The Past ◽  
The Relationship

The rise of e-commerce has brought considerable changes to the relationship between firms and consumers, especially within international business. Hence, understanding the use of such means for entering foreign markets has become critical for companies. However, the research on this issue is new and so it is important to evaluate what has been studied in the past. In this study, we conduct a systematic review of e-commerce and internationalisation studies to explicate how firms use e-commerce to enter new markets and to export. The studies are classified by theories and methods used in the literature. Moreover, we draw upon the internationalisation decision process (antecedents-modalities-consequences) to propose an integrative framework for understanding the role of e-commerce in internationalisation

The relationship between disaccharidase deficiencies and irritable bowel syndrome in childre - A literature review

2019 ◽  
Vol 3 (1) ◽  
Author(s):  
Mora V. Puertolas ◽  
Dianne N. Pagan ◽  
Roberto R. Andino ◽  
Amanda C. Fifi
Keyword(s):  
Irritable Bowel Syndrome ◽  
Literature Review ◽  
Irritable Bowel ◽  
The Relationship
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