scholarly journals REVIEW OF EVIDENCE BASED STUDY ON VYAGHRI HARITAKI AVALEHA WITH SPECIAL REFERENCE TO CERTAIN RESPIRATORY DISORDERS.

2021 ◽  
Vol 9 (01) ◽  
Author(s):  
ANJU SREEDHARAN
Keyword(s):  
Chronic Bronchitis ◽  
Clinical Studies ◽  
Health Sector ◽  
Immunomodulatory Activity ◽  
Evidence Based ◽  
Respiratory Disorders ◽  
Social Burden ◽  
Preventive Methods

ABSTRACT BACKGROUND Respiratory disorders are leading cause of morbidity and mortality that induces an economic and social burden worldwide. In today’s world, finding preventive methods and cure from these enormous challenges should be one of the priorities in the global health sector. Vyaghri haritaki avaleha is a potential Ayurveda polyherb formulation used for treating Kasa, Shwasa, Rajyakshma, Peenasa and its Rasayana properties ensures better quality of life of the patient. AIM AND OBJECTIVE Overview on Vyaghri haritaki avaleha To conduct a review on evidence-based study of Vyaghri haritaki avaleha in the management of symptoms of respiratory disorders. METHODS To conduct this study, Ayurveda research articles were obtained from Google Scholar. Total 6 studies were yielded, which included only Clinical and Pre-Clinical studies. RESULT Out of the 6 articles found (n=6), 1 article was an In-Vivo study and other 5 articles were Clinical studies on Vyaghri haritaki avaleha. Among the 5 Clinical studies, 1 study was found to be a comparative analysis between Vyaghri haritaki avaleha and Ashtang avaleha.1 study was found, where Anu taila Nasya was used as an adjuvant along with Vyaghri haritaki avaleha. Out of the 5 Clinical studies on Vyaghri haritaki avaleha, 3 studies were conducted on children. CONCLUSION This review on Vyaghri haritaki avaleha provides a better understanding of this formulation and showcases its effectiveness in treating all types of Kasa roga, Tamaka shwasa, Chronic bronchitis and Dusht Pratishaya. This review throws light on extensive use of Vyaghri haritaki avaleha in children for treating the symptoms of respiratory disorders. KEYWORDS Vyaghri haritaki avaleha, In Vivo, Clinical study, Respiratory disorders, Immunomodulatory activity, Tamaka Shwasa, Chronic Bronchitis.

scholarly journals Major considerations of dental care in COVID-19: an evidence-based on clinical studies and guidelines

2021 ◽  
Vol 2 (5) ◽  
Author(s):  
Milena Lazaro Zorzi ◽  
Leonardo Santos Lopes ◽  
Elias Naim Kassis
Keyword(s):  
Dental Care ◽  
Clinical Studies ◽  
Randomized Clinical Trials ◽  
Povidone Iodine ◽  
Evidence Based ◽  
Implant Dentistry ◽  
Antiseptic Solutions

Introduction: The COVID-19 pandemic has presented enormous challenges for dentists and patients. The risk of nosocomial transmission is a reality that requires the development of guidelines by the dental community to reduce the chances of infection by the new coronavirus. In this sense, it was necessary to implement alternative prophylactic techniques such as the adoption of oral rinses before dental care. Objective: To present the main considerations of clinical studies on dental care at COVID-19. Methods: The research was carried out from May 2021 to June 2021 and developed based on Scopus, PubMed, Science Direct, Scielo, and Google Scholar, following the Systematic Review-PRISMA rules. The quality of the studies was based on the GRADE instrument and the risk of bias was analyzed according to the Cochrane instrument. Results: One study showed that 0.2% chlorhexidine and 1% povidone-iodine oral solutions are effective pre-procedural mouthwashes against salivary SARS-CoV-2 in dental treatments. It was observed in another study that the effect of reducing the salivary load with mouthwash with CPC and PI was maintained after 6 hours. PVP-I nasal and oral antiseptic solutions are effective in inactivating SARS-CoV-2 at a range of concentrations after exposure times of 60 seconds. There is sufficient in vitro evidence to support the use of antiseptics to potentially reduce the viral load of SARS-CoV-2. The effects against the new coronavirus in vivo still need more randomized clinical trials to prove its effectiveness. Conclusion: ACE2 receptors are highly expressed in the oral cavity, therefore, this could be a potential high-risk route for SARS-CoV-2 infection. The virus can be detected in saliva even before the appearance of symptoms of COVID-19. In this regard, randomized clinical studies have shown that some pre-procedure oral mouthwashes are effective against salivary SARS-CoV-2 in dental treatments. In addition, the American Academy of Implant Dentistry (AAID) reported on how COVID-19 impacts dental care through guidelines for general dentistry.

Manangement Of Certain Respiratory Disorders Through Ayurveda: A Systematic Review Of Clinical Studies Published In Ayurveda Journal.

2021 ◽  
Vol 07 ◽  
Author(s):  
Anju Sreedharan ◽  
Nilesh Suryawanshi ◽  
Vedvati Bhapkar
Keyword(s):  
Systematic Review ◽  
Clinical Studies ◽  
Treatment Modalities ◽  
Chronic Obstructive ◽  
Screening Process ◽  
Major Health ◽  
Respiratory Disorders ◽  
Chronic Obstructive Pulmonary Diseases ◽  
Adults And Children

Background: Respiratory diseases like Asthma, Tuberculosis, COPD (Chronic Obstructive Pulmonary Diseases) in the developing world are a major health burden in terms of morbidity and mortality in both adults and children. A number of studies on treating respiratory disorders using Ayurveda formulations and its managements have been found in Ayurveda Journals with promising results, but an evidence based systematic review of them is not available. Objective: To conduct systematic review on the management of certain respiratory disorders through Ayurveda. Methods: To conduct this study, Ayurveda research articles were obtained from PubMed, Google Scholar. Total 51 Clinical studies were yielded which underwent further screening process to achieve the quality of inclusion criteria. Result: 24 articles were selected from six different publications for the review. In general, the quality of few selected articles was low. Of the 24 articles identified, 3 studies (n = 24) exclusively focused on Shodhana Karma (Vamana Virechana), 3 studies (n = 24) focused on the concept of Shodhana and Shamana Chikitsa, 4 studies (n = 24) focused on Ayurvedic formulations as adjuvants, 1 study (n = 24) focused on Shamana Chikitsa along with Pranayama, 13 studies (n = 24) focused only on Shamana Chikitsa. All the above treatment modalities showed significant results on major symptoms of respiratory disorders. Conclusion: This systematic review on different types of Ayurvedic management for treating respiratory disorders proves to be beneficial to understand the importance of Virechana Karma in Tamaka Swasa, effectiveness of Shamana Chikitsa after Shodhana Karma in Pratishaya and Tamaka Swasa .This review also throws light on the importance of Pranayama along with Shamana Chikitsa, efficacy of Ayurvedic formulations as adjuvant along with allopathic treatments and potency of different Ayurvedic dosage forms for treating certain respiratory disorders.

scholarly journals Efficacy and Safety of Pomegranate Medicinal Products for Cancer

2015 ◽  
Vol 2015 ◽  
pp. 1-15 ◽  
Author(s):  
Christian Vlachojannis ◽  
Benno F. Zimmermann ◽  
Sigrun Chrubasik-Hausmann
Keyword(s):  
Clinical Studies ◽  
Clinical Effectiveness ◽  
Published Data ◽  
Regulatory Guidance ◽  
Chemically Induced ◽  
Pubmed Search ◽  
Synthetic Drug

Preclinicalin vitroandin vivostudies demonstrate potent effects of pomegranate preparations in cancer cell lines and animal models with chemically induced cancers. We have carried out one systematic review of the effectiveness of pomegranate products in the treatment of cancer and another on their safety. The PubMed search provided 162 references for pomegranate and cancer and 122 references for pomegranate and safety/toxicity. We identified 4 clinical studies investigating 3 pomegranate products, of which one was inappropriate because of the low polyphenol content. The evidence of clinical effectiveness was poor because the quality of the studies was poor. Although there is no concern over safety with the doses used in the clinical studies, pomegranate preparations may be harmful by inducing synthetic drug metabolism through activation of liver enzymes. We have analysed various pomegranate products for their content of anthocyanins, punicalagin, and ellagic acid in order to compare them with the benchmark doses from published data. If the amount of coactive constituents is not declared, patients risk not benefiting from the putative pomegranate effects. Moreover, pomegranate end products are affected by many determinants. Their declaration should be incorporated into the regulatory guidance and controlled before pomegranate products enter the market.

Misophonia: An Evidence-Based Case Report

2020 ◽  
Vol 29 (4) ◽  
pp. 685-690
Author(s):  
C. S. Vanaja ◽  
Miriam Soni Abigail
Keyword(s):  
Quality Of Life ◽  
Case Report ◽  
Case History ◽  
Pure Tone ◽  
Physiological Responses ◽  
Evidence Based ◽  
Management Option ◽  
Pure Tone Audiogram

Purpose Misophonia is a sound tolerance disorder condition in certain sounds that trigger intense emotional or physiological responses. While some persons may experience misophonia, a few patients suffer from misophonia. However, there is a dearth of literature on audiological assessment and management of persons with misophonia. The purpose of this report is to discuss the assessment of misophonia and highlight the management option that helped a patient with misophonia. Method A case study of a 26-year-old woman with the complaint of decreased tolerance to specific sounds affecting quality of life is reported. Audiological assessment differentiated misophonia from hyperacusis. Management included retraining counseling as well as desensitization and habituation therapy based on the principles described by P. J. Jastreboff and Jastreboff (2014). A misophonia questionnaire was administered at regular intervals to monitor the effectiveness of therapy. Results A detailed case history and audiological evaluations including pure-tone audiogram and Johnson Hyperacusis Index revealed the presence of misophonia. The patient benefitted from intervention, and the scores of the misophonia questionnaire indicated a decrease in the severity of the problem. Conclusions It is important to differentially diagnose misophonia and hyperacusis in persons with sound tolerance disorders. Retraining counseling as well as desensitization and habituation therapy can help patients who suffer from misophonia.

Coaching Teachers to Enhance the Implementation Quality of Evidence-Based Programs

2013 ◽  
Author(s):  
Kimberly D. Becker ◽  
Dana Darney ◽  
Celene Domitrovich ◽  
Catherine Bradshaw ◽  
Nicholas S. Ialongo
Keyword(s):  
Evidence Based ◽  
Implementation Quality ◽  
Quality Of Evidence ◽  
Evidence Based Programs

Systematic review methodology for development: An example from microfinance

2018 ◽  
Vol 43 (1) ◽  
pp. 65-77 ◽  
Author(s):  
Carina Van Rooyen ◽  
Ruth Stewart ◽  
Thea De Wet
Keyword(s):  
Systematic Review ◽  
International Development ◽  
Health Sector ◽  
Evidence Based ◽  
Systematic Review Methodology ◽  
Development Interventions ◽  
The Us ◽  
Sub Saharan ◽  
The Impact ◽  
Evidence Based Decision Making

Big international development donors such as the UK’s Department for International Development and USAID have recently started using systematic review as a methodology to assess the effectiveness of various development interventions to help them decide what is the ‘best’ intervention to spend money on. Such an approach to evidence-based decision-making has long been practiced in the health sector in the US, UK, and elsewhere but it is relatively new in the development field. In this article we use the case of a systematic review of the impact of microfinance on the poor in sub-Saharan African to indicate how systematic review as a methodology can be used to assess the impact of specific development interventions.

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