Pontine and extra-pontine osmotic demyelination syndrome: Case report

Author(s):  
Eduardo dos Santos Sousa ◽  
◽  
Felipe Teijeiro Cabral ◽  
Annelise Akemi Higa Lee ◽  
Francisco Tomaz Meneses de Oliveira ◽  
...  

Osmotic demyelination syndrome is a rare disease, clinically presented as a global reduction in strength, tetraparesis, variations in the level of consciousness, and its content, and comatose status, associated with rapid variances in serum sodium levels (whether hyponatremia or hypernatremia). The neuroimaging findings are mainly in the pontine region, but currently the number of reports of extrapontine involvement has increased, typically with lesions in the topography of the thalamus, cerebellum, midbrain (substantia nigra), corpus callosum and hypothalamus. We display a rare case of pontine and extra-pontine involvement, even after the sodium replacement protocols of the current guidelines.

Author(s):  
Miguel García-Grimshaw ◽  
Amado Jiménez-Ruiz ◽  
José Luis Ruiz-Sandoval ◽  
Carlos Cantú-Brito ◽  
Erwin Chiquete

Author(s):  
Tiziana Carandini ◽  
Mattia Pozzato ◽  
Elisa Scola ◽  
Sabrina Avignone ◽  
Anna M Pietroboni

2013 ◽  
Vol 114 (1) ◽  
pp. 35-38
Author(s):  
Ömer Yılmaz ◽  
H. H. Armağn ◽  
A. Turan ◽  
M. Duymuş

The osmotic demyelination syndrome (ODS) has been identified as a complication of the rapid correction of hyponatremia for decades (King and Rosner, 2010). However, in recent years, a variety of other medical conditions have been associated with the development of ODS, independent of changes in serum sodium which cause a rapid changes in osmolality of the interstitial (extracellular) compartment of the brain leading to dehydration of energy-depleted cells with subsequent axonal damage that occurs in characteristic areas (King and Rosner, 2010). Slow correction of the serum sodium concentration and additional administration of corticosteroids seems to be a major prevention step in ODS patients. In the current report we aimed to share a rare case which we observed in our clinic.


1970 ◽  
Vol 21 (2) ◽  
pp. 170-173
Author(s):  
M Azizul Hoque ◽  
M Zahirul Haque ◽  
ABM Saiful Alam ◽  
AHM Tohurul Islam ◽  
DA Rashid ◽  
...  

We report a case of a middle aged lady who presented with alteration of consciousness and dysphasia. She was found to have hyponatremia which was corrected rapidly. After initial improvement, she subsequently developed marked deterioration of conscious level with upper motor sign signs in all four limbs. Osmotic demyelination syndrome was diagnosed by MRI. Severe hyponatremia carries a risk of cerebral edema with a significant mortality, but correcting it too rapidly can result in even more disastrous condition- osmotic demyelination syndrome. doi: 10.3329/taj.v21i2.3800   TAJ 2008; 21(2): 170-173


2015 ◽  
Vol 27 (4) ◽  
pp. 157 ◽  
Author(s):  
WaseemR Dar ◽  
NajeebU Sofi ◽  
Muzamil Latief ◽  
ImtiyazA Dar ◽  
Moomin Hussain

2022 ◽  
Vol 2 (1) ◽  
pp. 24-28
Author(s):  
哲朗 石田 ◽  
Murayama Tomonori

An 88-year-old right-handed man was admitted to our hospital for cognitive impairment and right-sided paralysis. His head non-contrast computed tomography (CT) showed large low-density areas (LDA) and fibrous structures in the left occipital and temporal lobe regions. Despite the fact that it had been more than 10 years since his stroke, rehabilitation was effective. This is a rare case in which cerebellar culmen -substantia nigra tract assisted rehabilitation after stroke.


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