Z-Score LORETA Neurofeedback as a Potential Therapy for ADHD

Biofeedback ◽  
2014 ◽  
Vol 42 (2) ◽  
pp. 74-81 ◽  
Author(s):  
J. Lucas Koberda ◽  
Paula Koberda ◽  
Andrew Moses ◽  
Jessica Winslow ◽  
Andrew Bienkiewicz ◽  
...  

Attention deficit hyperactivity disorder (ADHD) is a disorder of relatively high prevalence and frequently contributes to poor school and work performance. Neurofeedback (NFB) has proven to be an effective therapeutic modality in the treatment of ADHD. Recently introduced z-score LORETA neurofeedback offers promise as a tool, and appears to provide a more efficient therapy than standard two-channel neurofeedback. This advantage is based on the ability to train 19 channels simultaneously, and the ability to directly target an electrically dysregulated area of the brain, which may be more difficult to access with standard neurofeedback therapy (areas addressed with LORETA neurofeedback include the cingulate gyrus and hippocampal structures). This paper presents our experience with Z-score LORETA neurofeedback in the treatment of ADHD.

2019 ◽  
Author(s):  
Zeus Gracia-Tabuenca ◽  
Juan Carlos Díaz-Patiño ◽  
Isaac Arelio ◽  
Sarael Alcauter

AbstractThe functional organization of the brain network (connectome) has been widely studied as a graph; however, methodological issues may affect the results, such as the brain parcellation scheme or the selection of a proper threshold value. Instead of exploring the brain in terms of a static connectivity threshold, this work explores its algebraic topology as a function of the filtration value (i.e., the connectivity threshold), a process termed the Rips filtration in Topological Data Analysis. Specifically, we characterized the transition from all nodes being isolated to being connected into a single component as a function of the filtration value, in a public dataset of children with attention-deficit/hyperactivity disorder (ADHD) and typically developing children. Results were highly congruent when using four different brain segmentations (atlases), and exhibited significant differences for the brain topology of children with ADHD, both at the whole brain network and at the functional sub-network levels, particularly involving the frontal lobe and the default mode network. Therefore, this approach may contribute to identify the neurophysio-pathology of ADHD, reducing the bias of connectomics-related methods.HighlightsTopological Data Analysis was implemented in functional connectomes.Betti curves were assessed based on the area under the curve, slope and kurtosis.The explored variables were robust along four different brain atlases.ADHD showed lower areas, suggesting decreased functional segregation.Frontal and default mode networks showed the greatest differences between groups.Graphical Abstract


2019 ◽  
Vol 109 (3) ◽  
pp. 581-586 ◽  
Author(s):  
Shiran Leib ◽  
Tal Gilon Mann ◽  
Daniel Stein ◽  
Irena Vusiker ◽  
Itay Tokatly Latzer ◽  
...  

CNS Spectrums ◽  
2000 ◽  
Vol 5 (S3) ◽  
pp. s1-s8 ◽  
Author(s):  
Steven Pliszka ◽  
William W. Dodson ◽  
Thomas J. Spencer

ABSTRACTAttention-deficit/hyperactivity disorder (ADHD) is a genetic disorder that affects both children and adults. Genetic studies have shown the heritability of ADHD to be higher than other psychiatric disorders. In addition, imaging studies have revealed various structural anomalies in the brain.Often ADHD persists into adulthood. The presentation of ADHD into adulthood most often results from childhood onset of ADHD. Symptoms of inattention and functional behavior tend to persist. These symptoms may often be less obvious, with less overt hyperactivity and impulsiveness.Stimulant medications remain the predominant choice for the treatment of ADHD. They are safe and offer good response. Common adverse reactions can usually be removed by changing the dose and the timing of medication administration. Of the second-line agents for treating ADHD, the tricyclic antidepressants have generated the most studies and have proved fairly efficacious.


2016 ◽  
Vol 10 ◽  
pp. 274-282 ◽  
Author(s):  
Aaron T. Mattfeld ◽  
Susan Whitfield-Gabrieli ◽  
Joseph Biederman ◽  
Thomas Spencer ◽  
Ariel Brown ◽  
...  

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