Release kinetics of anti-inflammatory drug, and characterization and bioactivity of SiO2+PCL hybrid material synthesized by 
sol-gel processing

2014 ◽  
Vol 12 (3) ◽  
pp. 218-227 ◽  
Author(s):  
Michelina Catauro ◽  
Flavia Bollino
Keyword(s):  
Hybrid Material ◽  
Release Kinetics ◽  
Sol Gel ◽  
Inflammatory Drug ◽  
Anti Inflammatory ◽  
Gel Processing ◽  
Kinetics Of

Delivery of dexamethasone from electrospun PCL–PEO binary fibers and their effects on inflammation regulation

RSC Advances ◽  
2015 ◽  
Vol 5 (43) ◽  
pp. 34166-34172 ◽  
Author(s):  
Yan-Fang Li ◽  
Marina Rubert ◽  
Ying Yu ◽  
Flemming Besenbacher ◽  
Menglin Chen
Keyword(s):  
Gene Expression ◽  
Chemical Composition ◽  
Surface Topography ◽  
Release Kinetics ◽  
Related Gene ◽  
Inflammatory Drug ◽  
Anti Inflammatory ◽  
Kinetics Of

Differences in surface topography, chemical composition, wettability and release kinetics of the anti-inflammatory drug dexamethasone among different PCL–PEO fibers collectively affected the regulation of inflammatory related gene expression.

Characterization, bioactivity and ampicillin release kinetics of TiO2 and TiO24SiO2 synthesized by sol-gel processing

2006 ◽  
Vol 17 (5) ◽  
pp. 413-420 ◽  
Author(s):  
M. Catauro ◽  
M. G. Raucci ◽  
C. Convertito ◽  
D. Melisi ◽  
M. G. Rimoli
Keyword(s):  
Release Kinetics ◽  
Sol Gel ◽  
Gel Processing ◽  
Kinetics Of

Sol-gel processing of anti-inflammatory entrapment in silica, release kinetics, and bioactivity

2008 ◽  
Vol 87A (4) ◽  
pp. 843-849 ◽  
Author(s):  
M. Catauro ◽  
D. Melisi ◽  
A. Curcio ◽  
M.G. Rimoli
Keyword(s):  
Release Kinetics ◽  
Sol Gel ◽  
Anti Inflammatory ◽  
Gel Processing

Thermal Analysis Kinetics of Pd-Doped SiO2 Organic-Inorganic Hybrid Material

2017 ◽  
Vol 727 ◽  
pp. 272-279 ◽  
Author(s):  
Jing Yang ◽  
Hong Jun Li ◽  
Rui Hua Mu ◽  
Ya Mei Zhao ◽  
Zhi Tong
Keyword(s):  
Thermal Decomposition ◽  
Hybrid Material ◽  
Sol Gel ◽  
Kinetic Mechanism ◽  
Exponential Factor ◽  
Inorganic Hybrid ◽  
Inorganic Hybrid Material ◽  
Exponential Factors ◽  
Thermal Analysis Kinetics ◽  
Kinetics Of

Pd-doped SiO2 organic-inorganic hybrid material (Pd/M-SiO2) was prepared by sol-gel method and characterized by XRD, FTIR spectra and TG/DTG analysis. The most probable kinetic mechanism function, apparent activation energy and pre-exponential factor of the thermal decomposition for Pd/M-SiO2 material were calculated using the combined Coast-Redfern intergral and Αchar differential methods. Pd element in noncalcined Pd/M-SiO2 materials exists in PdCl2 form. FTIR spectroscopy confirmed the existence of hydrophobic Si−CH3 groups. The thermal decomposition process of Pd/M-SiO2 materials can be divided into four stages, with different mechanism functions. The activation energies are 76.37, 146.85, 208.90 and 413.89 kJ·mol−1 for the four stages, respectively, and the pre-exponential factors are 5.04×1012, 7.14×1013, 2.93×1012 and 6.56×1019 s−1, respectively. There is no obvious influence of the existence of metallic Pd0 on the thermal decomposition of methyl.

Effect of the Sol-Gel Synthesis Parameters on the Incorporation of an Anti-inflammatory Drug in a Ceramic Material

2007 ◽  
Vol 1007 ◽  
Author(s):  
Aracely Hernandez ◽  
Patricia Esquivel-Ferriño ◽  
Idalia Gomez ◽  
Lucia Cantu
Keyword(s):  
Ceramic Material ◽  
Sol Gel ◽  
Nitrogen Adsorption ◽  
Molar Ratio ◽  
Inflammatory Drug ◽  
Synthesis Conditions ◽  
Synthesis Parameters ◽  
Anti Inflammatory ◽  
Drug Incorporation ◽  
Sol Gel Synthesis

ABSTRACTIn the present work, sol-gel method was used to incorporate in a ceramic material a non steroidal anti-inflammatory drug (piroxicam) as model drug. The incorporation of the drug in the SiO2 network was carried out at different sol-gel synthesis parameters, such as pH (3 and 5) and the alkoxide/water ratio (1:6 and 1:8). The biomaterial obtained was analyzed by thermal analysis TGA-DTA, infrared spectroscopy (FTIR), Scanning Electronic Microscopy (SEM) and X-ray diffraction (XRD); specific surface area and porosity were analyzed from nitrogen adsorption isotherm. Better drug incorporation into the material was achieved at the synthesis conditions of pH 5 and 1:6 alkoxide/water molar ratio.

Sol-gel processing of drug delivery materials and release kinetics

2005 ◽  
Vol 16 (3) ◽  
pp. 261-265 ◽  
Author(s):  
F. De Gaetano ◽  
L. Ambrosio ◽  
M. G. Raucci ◽  
A. Marotta ◽  
M. Catauro
Keyword(s):  
Drug Delivery ◽  
Release Kinetics ◽  
Sol Gel ◽  
Gel Processing

Effect of Thermal Treatment of Sol-Gel Titania Reservoirs on Release Kinetics of Phenytoin

2012 ◽  
Vol 95 (6) ◽  
pp. 2022-2027
Author(s):  
Anna Kozina ◽  
Karla A. Espinoza ◽  
Emma Ortiz-Islas ◽  
Ignacio A. Rivero
Keyword(s):  
Thermal Treatment ◽  
Release Kinetics ◽  
Sol Gel ◽  
Kinetics Of

scholarly journals Antibacterial Activity and Iron Release of Organic-Inorganic Hybrid Biomaterials Synthesized via the Sol-Gel Route

2021 ◽  
Vol 11 (19) ◽  
pp. 9311
Author(s):  
Michelina Catauro ◽  
Ylenia D’Errico ◽  
Antonio D’Angelo ◽  
Ronald J. Clarke ◽  
Ignazio Blanco
Keyword(s):  
Hybrid Materials ◽  
Release Kinetics ◽  
Sol Gel ◽  
Antibacterial Properties ◽  
Iron Release ◽  
Biological Characterization ◽  
Visible Spectroscopy ◽  
E Coli ◽  
Hybrid Biomaterials ◽  
Kinetics Of

The aim of this work was the synthesis of hybrid materials of iron (II)-based therapeutic systems via the sol-gel method. Increasing amounts of polyethylene glycol (PEG 6, 12, 24, 50 wt%) were added to SiO2/Fe20 wt% to modulate the release kinetics of the drug from the systems. Fourier-transform infrared (FTIR) spectroscopy was used to study the interactions between different components in the hybrid materials. The release kinetics in a simulated body fluid (SBF) were investigated, and the amount of Fe2+ released was detected via ultraviolet-visible spectroscopy (UV-Vis) after reaction with ortho-phenanthroline. Furthermore, biological characterization was carried out. The bioactivity of the synthesized hybrid materials was evaluated via the formation of a layer of hydroxyapatite on the surface of samples soaked in SBF using spectroscopy. Finally, the potential antibacterial properties of seven different materials against two different bacteria—E. coli and S. aureus—were investigated.

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