Changes in Inflammatory Markers during a Hemodialysis Session and Their Relation to Vascular Access Type

2012 ◽  
Vol 13 (4) ◽  
pp. 446-451 ◽  
Author(s):  
Benaya Rozen-Zvi ◽  
Arie Erman ◽  
Asher Korzets ◽  
Rachel S. Levy-Drummer ◽  
Avry Chagnac ◽  
...  
Keyword(s):  
Vascular Access ◽  
Inflammatory Markers ◽  
Hemodialysis Session

Effect of a single hemodialysis session on inflammatory markers

2010 ◽  
Vol 14 (4) ◽  
pp. 411-417 ◽  
Author(s):  
Aparna R. BITLA ◽  
Prabhakar E. REDDY ◽  
Suchitra M. MANOHAR ◽  
Sivakumar V. VISHNUBHOTLA ◽  
Srinivasa Rao PEMMARAJU VENKATA LAKSHMI NARASIMHA
Keyword(s):  
Inflammatory Markers ◽  
Hemodialysis Session

scholarly journals Cross-Talk between Inflammation, Coagulation/Fibrinolysis and Vascular access in Hemodialysis Patients

2008 ◽  
Vol 9 (4) ◽  
pp. 248-253 ◽  
Author(s):  
E. Costa ◽  
S. Rocha ◽  
P. Rocha-Pereira ◽  
E. Castro ◽  
F. Reis ◽  
...  
Keyword(s):  
Endothelial Cell ◽  
Plasminogen Activator ◽  
Vascular Access ◽  
Inflammatory Markers ◽  
Cell Function ◽  
Hemoglobin Concentration ◽  
Plasminogen Activator Inhibitor ◽  
Endothelial Cell Function ◽  
Human Erythropoietin ◽  
Pai 1

This work aimed to study the association between fibrinolytic/endothelial cell function and inflammatory markers in chronic kidney disease (CKD) patients undergoing hemodialysis (HD) and recombinant human erythropoietin (rhEPO) therapies, and its relationship with the type of vascular access (VA) used for the HD procedure. As fibrinolytic/endothelial cell function markers we evaluated plasminogen activator inhibitor type-1 (PAI-1), tissue plasminogen activator (tPA) and D-dimers, and as inflammatory markers; C-reactive protein (CRP), soluble interleukin (IL)-2 receptor (s-IL2R), IL-6 and serum albumin levels. The study was performed in 50 CKD patients undergoing regular HD, 11 with a central venous dialysis catheter (CVC) and 39 with an arteriovenous fistula (AVF), and in 25 healthy controls. Compared to controls, CKD patients presented with significantly higher levels of CRP, s-IL2R, IL-6 and D-dimers, and significantly lower levels of PAI-1. The tPA/PAI-1 ratio was significantly higher in CKD patients. We also found statistical significant correlations in CKD patients between D-dimers levels and inflammatory markers: CRP, albumin, s-IL2R and IL-6. When comparing the two groups of CKD patients, we found that those with a CVC presented statistically significant lower levels of hemoglobin concentration and albumin, and higher levels of CRP, IL-6, D-dimers and tPA. Our results showed an association between fibrinolytic/endothelial cell function and increased inflammatory markers in CKD patients. The increased levels of D-dimer, tPA and inflammatory markers in CKD patients using a CVC, led us to propose a relationship between the type of VA chosen for HD, and the risk of thrombogenesis.

scholarly journals Predicting Arteriovenous Fistula Non-Maturation in Hemodialysis Patients: Analytics of Inflammatory Markers and Serum Metabolic Values

2019 ◽  
Author(s):  
Akram Nakhaei ◽  
Mohammad Mehdi Sepehri ◽  
Pejman Shadpour ◽  
Morteza Khavanin Zadeh
Keyword(s):  
Confidence Interval ◽  
Arteriovenous Fistula ◽  
Vascular Access ◽  
Inflammatory Markers ◽  
Population Aging ◽  
White Blood Cells ◽  
Chronic Hemodialysis ◽  
Distribution Width ◽  
Endovascular Interventions ◽  
Background Population

Abstract Background Population aging has brought a rise in the prevalence of diabetes and hypertension, leading to more cases of renal failure. Hemodialysis, as a method of renal replacement therapy, by far prevails over peritoneal dialysis (93.5% vs. 6.5%). Although arteriovenous fistula (AVF) is frequently chosen as the vascular access route for chronic hemodialysis; it has limitations including non-maturation. As maintenance of an AVF is much more costly than its creation, foreseeing maturation failure can lead to a wiser allocation of patients to AVF surgery or other alternatives, with potential for significant cost containment.Methods We investigated the relationship of routinely available systemic inflammatory markers and baseline metabolic values in 107 end-stage renal disease patients (over 35 years of age undergoing their first brachio-cephalic AVF access surgery at wrist level for chronic hemodialysis). In this study, for the first time to our knowledge, we applied predictive analytic tools such as Random Forest for retrospective analysis of prospectively collected data between 2011 and 2018.Results Our results showed that a combination of inflammatory markers and serum metabolic values can prognosticate AVF maturation outcomes with an accuracy of 0.723, by the 95% confidence interval of (0.715, 0.731) and AUC of 0.853. Also, a combination of inflammatory markers, including albumin, c-reactive protein, erythrocyte sedimentation rate, hemoglobin, lymphocytes, neutrophils, white blood cells, platelets, and red blood cell distribution width, can prognosticate AVF maturation outcomes with an accuracy of 0.674, by the 0.95 confidence interval of (0.665, 0.684) and AUC of 0.824.Conclusion Risk stratification of patients for AVF non-maturation before attempting the first AVF surgery may help prevent multiple surgical failures and costly endovascular interventions by allowing vascular surgeons to make an individualized choice of vascular access method for new patients.

699 Late increase of inflammatory markers in patients with recent onset atrial fibrillation is related with cardioversion outcome

2007 ◽  
Vol 6 (1) ◽  
pp. 154-154
Author(s):  
A KALOGEROPOULOS ◽  
A RIGOPOULOS ◽  
S PAPATHANASIOU ◽  
S TSIODRAS ◽  
S DRAGOMANOVITS ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Inflammatory Markers ◽  
Recent Onset ◽  
Onset Atrial Fibrillation

Pseudoaneurysm of the brachial artey in two infants following accidental artertial puncture

VASA ◽  
2005 ◽  
Vol 34 (3) ◽  
pp. 198-200 ◽  
Author(s):  
Yilmaz ◽  
Dogan ◽  
Tok ◽  
Hazirolan ◽  
Guvener ◽  
...  
Keyword(s):  
Blunt Trauma ◽  
Vascular Access ◽  
Brachial Artery ◽  
Fibrous Tissue ◽  
Arterial Puncture ◽  
Artery Pseudoaneurysm

A pseudoaneurysm is defined as an aneurysmatic sac surrounded by fibrous tissue instead of other vascular layers such as the muscular one. It is a rare incident in infants especially in the brachial artery. Blunt trauma and vascular access attempts are the most common etiologic factors. We present two infants with brachial artery pseudoaneurysm in the antecubital region following accidental arterial puncture.

Multidisciplinary management of vascular access for haemodialysis: from the preparation of the initial access to the treatment of stenosis and thrombosis

VASA ◽  
2011 ◽  
Vol 40 (3) ◽  
pp. 188-198 ◽  
Author(s):  
Reinhold ◽  
Haage ◽  
Hollenbeck ◽  
Mickley ◽  
Ranft
Keyword(s):  
Vascular Access ◽  
Central Venous ◽  
Advantages And Disadvantages ◽  
Multidisciplinary Study ◽  
First Results ◽  
Lower Complication ◽  
Lower Complication Rate ◽  
Access Problems ◽  
Arteriovenous Grafts ◽  
The Individual

In February 2008 a multidisciplinary study group was established in Germany to improve the treatment of patients with potential vascular access problems. As one of the first results of their work interdisciplinary recommendations for the management of vascular access were provided, from the creation of the initial access to the treatment of complications. As a rule the wrist arteriovenous fistula (AVF) is the access of choice due to its lower complication rate when compared to other types of access. The AVF should be created 3 months prior to the expected start of haemodialysis to allow for sufficient maturation. Second and third choice accesses are arteriovenous grafts (AVG) and central venous catheters (CVC). Ultrasound is a reliable tool for vessel selection before access creation, and also for the diagnosis of complications in AVF and grafts. Access stenosis and thrombosis can be treated surgically and interventionally. The comparison of both methods reveals advantages and disadvantages for each. The therapeutic decision should be based on the individual patients’ constitution, and also on the availability and experience of the involved specialists.

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