Acute Hydrops with Micro-Cornea – an Extremely Rare Condition: A Case Report

Purpose To report the first case of a one-eyed child with micro-cornea, coloboma of iris and acute hydrops without any other disorder of the cornea or systemic disease. Methods Intracameral injection of perfluoro propane (C3F8) gas was performed under general anaesthesia. Results Resolution of the hydrops was observed at 1st week of follow-up, which was confirmed by anterior segment optical coherence tomography. Patient was subsequently lost to follow-up. Conclusions Intracameral injection of perfluoro propane gas is an effective way to quickly resolve acute hydrops. In this specific case, the patient presented with micro-cornea and no other corneal abnormalities.

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Optical Coherence Tomography Angiography of Iris Nevus: A Case Report

Case Reports in Ophthalmology ◽

10.1159/000450572 ◽

2016 ◽

Vol 7 (3) ◽

pp. 450-456 ◽

Cited By ~ 7

Author(s):

Davide Allegrini ◽

Giovanni Montesano ◽

Alfredo Pece

Keyword(s):

Optical Coherence Tomography ◽

Case Report ◽

Optical Coherence Tomography Angiography ◽

Anterior Segment ◽

Ultrasound Biomicroscopy ◽

Vascular Network ◽

Optical Coherence ◽

Early Phases ◽

Iris Nevus

Iris nevus is common: 6% of patients with suspected iris melanoma have lesions other than melanoma, and 36% of them are nevi. Iris nevus turns into melanoma in approximately 8% of cases at a mean of 15 years. This case report provides the first description of an iris tumor examined with iris optical coherence tomography angiography (OCTA) compared to iris fluorescein angiography (IFA). A 60-year-old man with a diagnosis of iris nevus in the left eye was referred to our department for IFA and iris OCTA. The iris vasculature in IFA was visible only in the early phases, but not clearly. OCTA, however, gave visualization of the vascular network and very precisely defined the vessels of the whole lesion, except for the pupillary portion, which was masked by superficial pigment accumulations. IFA and iris OCTA can add information about the vascular architecture compared to slit-lamp biomicroscopy, ultrasound biomicroscopy, and anterior-segment OCT. However, IFA is time-consuming and invasive and can – very occasionally – cause serious adverse reactions. In contrast, OCTA defines the texture of the iris vasculature better. In conclusion, OCTA is a new method, easy to execute, needing no dye injection, and provides useful information on the vascular network of iris lesions. It could therefore be helpful in the diagnosis and follow-up of these lesions.

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Necrotizing Anterior Scleritis in a Woman with Terrien’s Marginal Degeneration: A Case Report

The Open Ophthalmology Journal ◽

10.2174/1874364102115010318 ◽

2021 ◽

Vol 15 (1) ◽

pp. 318-321

Author(s):

María Alejandra Fonseca-Mora ◽

Paula Tatiana Muñoz-Vargas ◽

Juliana Reyes-Guanes ◽

William Rojas-Carabali ◽

Miguel Cuevas ◽

...

Keyword(s):

Case Report ◽

Systemic Disease ◽

Immunosuppressive Treatment ◽

Disease Association ◽

Slit Lamp ◽

Systemic Corticosteroids ◽

First Case ◽

Anterior Scleritis ◽

Inflammatory Component

Purpose: The aim of the study was to report the first case of a patient with Terrien’s Marginal Degeneration (TMD) who developed necrotizing anterior scleritis without systemic disease association, requiring systemic immunosuppressive treatment. Case Report: A 32-year-old female consulted for bilateral ocular burning and hyperemia. Initially, she was diagnosed with conjunctivitis and treated with topical antibiotics and corticosteroids, with mild transitory improvement but the progression of the disease. Years later, she attended the ocular immunology consultation for a second opinion where TMD with ocular inflammatory component OU was diagnosed. Seven months later, she presented with severe pain, decreased visual acuity, and photophobia in OS. At the slit-lamp examination, necrotizing anterior scleritis with a high risk of perforation in OS was observed. The patient was referred to the rheumatologist and started treatment with systemic corticosteroids and cyclophosphamide, exhibiting a clinical improvement. The patient did not meet the criteria for any systemic illness associated with scleritis, such as autoimmune diseases or vasculitis. Thus, scleritis was related to the adjacent inflammatory process associated with TMD, as an atypical presentation of this disease. Conclusion: Although an inflammatory type of TMD has been proposed, it is essential to follow up closely these patients and consider necrotizing anterior scleritis, a severe ocular disease that requires prompt immunosuppressive management, as a possible atypical associated presentation of this disease.

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Twelve-year follow up of a case of autosomal recessive bestrophinopathy with transient resolution of retinal edema in one eye

European Journal of Ophthalmology ◽

10.1177/11206721211073211 ◽

2022 ◽

pp. 112067212110732

Author(s):

Lidia Remolí Sargues ◽

Clara Monferrer Adsuara ◽

Raquel Rodríguez López ◽

Roberto Gallego Pinazo ◽

Javier Montero Hernández ◽

...

Keyword(s):

Case Report ◽

Fundus Autofluorescence ◽

Anterior Segment ◽

Subretinal Fluid ◽

Posterior Pole ◽

Dietary Therapy ◽

Retinal Edema ◽

Blurred Vision ◽

First Case

Purpose To report 12-year follow-up of a patient with ARB. Case report A 25-year-old man presented with blurred vision in his both eyes (OU). Best-corrected visual acuity (BCVA) was 20/63 Snellen equivalent in the right eye (OD) and 20/32 Snellen equivalent in the left eye. The intraocular pressures and anterior segment examination were unrevealing in OU. Posterior segment examination revealed multiple yellowish flecks and dots in the posterior pole in OU. Optical coherence tomography (OCT) showed subretinal fluid (SRF), intraretinal hyporeflective spaces, elongated and shaggy photoreceptors and outer retinal defects. Fundus autofluorescence demonstrated mottling hyperautofluorescence and hypoautofluorescence in the posterior pole in OU. Fluorescein angiography illustrated hyperfluorescence in the posterior pole and surrounding the arcades in OU. Multifocal electroretinography objectified mild to markedly abnormal responses in all ring areas in OU. Molecular genetic testing confirmed two heterozygous sequence variations in the BEST1 gene. At 4 years of follow-up, OCT revealed a complete resolution of SRF and a partial resolution of intraretinal hyporeflective spaces in the OD with corresponding improvement in the BCVA to 20/23 Snellen equivalent in the OD, even though outer retinal defects persisted. Our patient denied recent changes in his alimentary habits and medical history at that time. Posteriorly, SRF and intraretinal hyporeflective spaces reappeared in the OD. Conclusion To the best of our knowledge, this is the first case report of ARB with a transient resolution of retinal edema in one eye without medical treatment and dietary therapy.

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Anaphylactic Bronchospasm during Induction of General Anaesthesia: A Case Report

Journal of Nepal Medical Association ◽

10.31729/jnma.4304 ◽

2019 ◽

Vol 57 (218) ◽

Cited By ~ 1

Author(s):

Binod Gautam ◽

Rashna Shakya

Keyword(s):

Case Report ◽

General Anaesthesia ◽

Clinical Manifestation ◽

Early Recognition ◽

Air Flow ◽

Alveolar Air ◽

Lost To Follow Up ◽

Prompt Attention

Bronchospasm represents the clinical manifestation of bronchial muscles contraction resultingin reduced alveolar air flow. Non-allergic mechanisms or anaphylaxis underlie the genesis ofperioperative bronchospasm, a potential anaesthetic disaster. Early recognition and treatmentare crucial. We report a rare incident of anaphylactic bronchospasm without hypotension duringgeneral anaesthesia. Urticaria appeared in chest and abdomen suggesting anaphylaxis. After theevent resolved with bronchodilators, surgery continued uneventfully. Vecuronium was the mostprobable culprit but confirmation was not possible as the patient was lost to follow up. Rarely,perioperative anaphylaxis presents only with bronchospasm that requires prompt attention to avoidadverse outcome.

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Lost to follow-up in classic congenital adrenal hyperplasia: a case report

Endocrine Abstracts ◽

10.1530/endoabs.63.ep12 ◽

2019 ◽

Author(s):

Costa Cristiana Gomes da ◽

Tania Matos ◽

Vale Sonia do

Keyword(s):

Case Report ◽

Congenital Adrenal Hyperplasia ◽

Adrenal Hyperplasia ◽

Classic Congenital Adrenal Hyperplasia ◽

Lost To Follow Up

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The Use of Anterior-Segment Optical-Coherence Tomography for the Assessment of the Iridocorneal Angle and Its Alterations: Update and Current Evidence

Journal of Clinical Medicine ◽

10.3390/jcm10020231 ◽

2021 ◽

Vol 10 (2) ◽

pp. 231

Author(s):

Giacinto Triolo ◽

Piero Barboni ◽

Giacomo Savini ◽

Francesco De Gaetano ◽

Gaspare Monaco ◽

...

Keyword(s):

Optical Coherence Tomography ◽

Intraocular Pressure ◽

Clinical Relevance ◽

Anterior Segment ◽

Angle Closure ◽

Current Evidence ◽

Optical Coherence ◽

Iridocorneal Angle ◽

Wide Range

The introduction of anterior-segment optical-coherence tomography (AS-OCT) has led to improved assessments of the anatomy of the iridocorneal-angle and diagnoses of several mechanisms of angle closure which often result in raised intraocular pressure (IOP). Continuous advancements in AS-OCT technology and software, along with an extensive research in the field, have resulted in a wide range of possible parameters that may be used to diagnose and follow up on patients with this spectrum of diseases. However, the clinical relevance of such variables needs to be explored thoroughly. The aim of the present review is to summarize the current evidence supporting the use of AS-OCT for the diagnosis and follow-up of several iridocorneal-angle and anterior-chamber alterations, focusing on the advantages and downsides of this technology.

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First reported case of penile prosthesis infection from brucellosis: case report

African Journal of Urology ◽

10.1186/s12301-020-00090-1 ◽

2020 ◽

Vol 26 (1) ◽

Author(s):

Nabil Nabil Moohialdin ◽

Ahmad Shamsodini ◽

Steven K. Wilson ◽

Osama Abdeljaleel ◽

Ibrahim Alnadhari ◽

...

Keyword(s):

Case Report ◽

Broad Spectrum ◽

Surgical Intervention ◽

Penile Prosthesis ◽

Raw Milk ◽

Prosthesis Infection ◽

Case Presentation ◽

First Case ◽

Milk Ingestion

Abstract Background Infection after the penile prosthesis can be devastating to both the patient and surgeon with various complications and consequences. After introduction of antibiotic-coated implants, the rate of infection has dramatically decreased, but still we see uncommon organisms causing infection. We present a first case report of penile prosthesis infection by brucellosis due to raw milk ingestion. To our knowledge, this is the first reported case of brucellosis penile prosthesis infection. Case presentation We present a first case report of penile prosthesis infection by brucellosis due to raw milk ingestion. A 75-year-old, diabetic male patient presented with penile prosthesis infection 5 months post-penile exchange surgery due to mechanical malfunctioning of 2-piece penile prosthesis which was inserted 11 years ago. The initial treatment with broad spectrum antibiotics did not subside the infection. After diagnosis of brucellosis, the antibiotic was changed to anti-brucellosis (Rifampicin + Tetracycline). The patient improved dramatically and was discharged home with smooth follow-up course. Conclusion Brucellosis can cause infection of penile prosthesis and can be treated with anti-brucellosis antibiotics without necessitating surgical intervention and removal of prosthesis.

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Lactotransferrin-Related Breast Amyloidosis: Report of a First Case

International Journal of Surgical Pathology ◽

10.1177/10668969211016053 ◽

2021 ◽

pp. 106689692110160

Author(s):

Mingfei Yan ◽

Mark Rodgers ◽

Aparna Harbhajanka ◽

Hannah Gilmore

Keyword(s):

Breast Lesion ◽

Hematologic Malignancy ◽

Genetic Disorders ◽

Rare Condition ◽

Myoepithelial Cells ◽

Hematological Disorders ◽

First Case ◽

Benign Nature ◽

Extensive Involvement

Breast amyloidosis is a rare condition which is mostly associated with hematological disorders or hereditary genetic disorders. Imaging findings of breast amyloidosis can mimic malignancy, which often leads to biopsy or excision of the lesion. Here, we presented a case of localized lactotransferrin-related breast amyloidosis in an elderly female patient. Histologic examination revealed extensive involvement of breast lobules by amorphous amyloid materials, with attenuation of lobular structures and prominent calcifications. Positive immunostains for myoepithelial cells helped to exclude the possibility of invasive carcinoma. The patient had no hematologic malignancy besides immunoglobulin G lambda monoclonal gammopathy of undetermined significance. Mass spectrometry of the breast amyloid identified lactotransferrin and no immunoglobulin or its light chain. On follow-up, the patient showed no recurrence of the breast lesion after local excision nor showed other systematic comorbidities, indicating the benign nature of the lesion. This first report of lactotransferrin-related amyloidosis may represent a special type of localized breast amyloidosis that has no correlation with systematic disorders.

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Accidental Corneal Intrastromal Intraocular Lens Implantation with the Wound-Assisted Technique and Clinical Course with Anterior Segment Optical Coherence Tomography

Case Reports in Ophthalmology ◽

10.1159/000514068 ◽

2021 ◽

pp. 283-287

Author(s):

Jo Moriya ◽

Shinichi Sakamoto ◽

Satoru Inoda ◽

Hidenori Takahashi ◽

Hidetoshi Kawashima

Keyword(s):

Optical Coherence Tomography ◽

Intraocular Lens ◽

Anterior Segment ◽

Corneal Stroma ◽

Age Related Macular Degeneration ◽

Optical Coherence ◽

Corrected Visual Acuity ◽

Age Related ◽

Intracameral Injection ◽

Air Tamponade

Accidental intraocular lens (IOL) implantation into the corneal stroma is a rare clinical entity that can occur during the wound-assisted technique. In this report, we describe a case of an 81-year-old man who underwent cataract surgery in which the IOL was implanted into the corneal stroma with the wound-assisted technique, and we present changes in anterior segment optical coherence tomography. The IOL was removed and reinserted after widening the incision. Air tamponade was created by intracameral injection. An anterior chamber tap was performed 10 h later to reduce increased intraocular pressure. Interlayer separation of the corneal stroma was confirmed 30 min postoperatively but was corrected 4 days later. The patient’s best-corrected visual acuity (BCVA) was logMAR 0.30, and he had been diagnosed with age-related macular degeneration before surgery. Although the opacity of the corneal stroma persisted, BCVA improved to logMAR 0. When using the wound-assisted technique for IOL insertion, surgeons should take care not to implant the IOL into the corneal stroma.

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