Retrospective Evaluation of Three Treatment Methods for Primary Hyperparathyroidism in Dogs

2007 ◽  
Vol 43 (2) ◽  
pp. 70-77 ◽  
Author(s):  
Liberty Rasor ◽  
Rachel Pollard ◽  
Edward C. Feldman

The medical records of 110 dogs treated for primary hyperparathyroidism were reviewed. Dogs were treated via parathyroidectomy (n=47), percutaneous ultrasound-guided ethanol ablation (n=15), or percutaneous ultrasound-guided heat ablation (n=48). Forty-five of 48 (94%) parathyroidectomies resulted in control of hypercalcemia for a median of 561 days. Thirteen of 18 (72%) ethanol ablation procedures resulted in control of hypercalcemia for a median of 540 days. Forty-four of 49 (90%) heat-ablation treatments resulted in control of hypercalcemia for a median of 581 days.

2018 ◽  
Vol 5 (4) ◽  
pp. 91
Author(s):  
Rodolfo Oliveira Leal ◽  
Laura Frau Pascual ◽  
Juan Hernandez

Percutaneous ultrasound-guided radiofrequency heat-ablation (UG-RHA) is a therapeutic option for dogs with primary hyperparathyroidism (PHPTH) but information about its outcome is still controversial. This retrospective study aimed to evaluate the outcome and complications of UG-RHA in dogs with PHPTH. The medical records of dogs with PHPTH submitted to UG-RHA between June 2012 and September 2015 in a French referral center were retrospectively reviewed. Eight cases were included. No sex predisposition was found. The median age at diagnosis was 12 years. The most common clinical sign was polyuria/polydipsia. All of the dogs were hypercalcaemic prior to UG-RHA, and all showed a parathyroid nodule identified upon cervical ultrasound. UG-RHA was uneventful, allowing a successful resolution of hypercalcemia in all dogs (8/8). Six out of eight dogs did not receive vitamin D supplementation either pre- or post-procedure. From these, three dogs developed biochemical hypocalcemia, but only one required therapy. Other short-term complications included Horner’s syndrome (1/8) and aspiration bronchopneumonia, which led to cardio-respiratory arrest in one large-breed dog (1/8). Long-term complications were scarce, with no recurrence reported in all of the cases that were assessed in follow-up (4/7). This study demonstrates that UG-RHA has few short or long-term complications, and it is a good therapeutic alternative for dogs with PHPTH.


Animals ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 1648
Author(s):  
Theresa Tschoner ◽  
Yury Zablotski ◽  
Melanie Feist

Lameness is often diagnosed in cattle with left displacement of the abomasum (LDA). Laterality of lying has an effect on the etiology of LDA, and lame cows prefer to lie on the affected limb. The objective of this study was to investigate the possible association between laterality of claw lesion and presence of LDA. The medical records of 252 cattle presented with a diagnosis of LDA and subjected to a diagnostic examination of claw lesions over a period of 11 years (2009–2019), were analyzed retrospectively. Data were evaluated for presence and localization of claw lesion, concentrations of inflammatory markers, and abomasal rolling as therapy. At least one claw lesion was diagnosed in 46.4% of cattle. There was no association between laterality of claw lesion and LDA. Presence of claw lesion or oral drench and/or analgesic treatment did not have an effect on occurrence of relapse. A high number of cattle was diagnosed with both LDA and claw lesions. Focus should lie on preventing painful claw lesions in the dry and the early post-partum period. The high recurrence rate after abomasal rolling suggests that abomasal rolling should only be considered as a therapy for temporary relief, and surgical procedures should be discussed with farmers.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Kan Wu ◽  
Chunjie Li ◽  
Zheng Yang ◽  
Shangchun Yang ◽  
Wenbing Yang ◽  
...  

Abstract Background Further understanding of the distribution and changing characteristics of dental diseases is of great significance for all dental emergency centers for strengthening the medical staff’s treatment knowledge abilities and effective use of emergency resources in the face of public health emergencies involving highly infectious respiratory diseases. Methods The medical records of 4158 dental emergency patients in 2019 and 2020 were retrospectively analyzed and divided into pre-SARS-COV-2 group and SARS-COV-2 group according to time. The demographic data, date and time, diagnosis, and treatment methods of the two groups were statistically described, and the chi-squared test was used to analyze the differences. The medical records of 4158 dental emergency patients during the same period of two years in 2019 and 2020 were retrospectively analyzed and divided into SARS-COV-2 pre-group and SARS-COV-2 group according to time. The demographic data, date and time, diagnosis and treatment methods of the two groups were statistically described, and the chi-square test was used to determine the differences. Results During the SARS-COV-2 pandemic, the number of dental emergency visits increased by 29.7%. During the pandemic, males (n = 286, 58.1%) were more likely to visit dental emergency centers for trauma than females (n = 206, 41.9%) (P < 0.05); females (n = 242, 60.8%) were more likely to visit dental emergency centers for acute gingivitis and acute pericoronitis than males (n = 156, 39.2%) (P < 0.05). A major change in diagnosis was related to acute pulpitis (K04.0) and acute apical periodontitis (K04.4), which increased by 9.2%; acute gingivitis (K05.0) and acute pericoronitis (K05.2) increased by 3.5%; open wound of the lip and oral cavity (S01.5) decreased by 17.9%; other conditions (non-emergency diseases) increased by 6.8%, compared with the pre-SARS-COV-2 period. Among the treatment modalities, during the pre-SARS-COV-2 period, 304 patients (17.7%) received a prescription for antibiotics and analgesics, and 1485 (86.5%) received a prescription for local treatment. During the SARS-COV-2 period, 958 (39.2%) received a prescription for antibiotics and analgesics, and 1636 (67.0%) received a prescription for local treatment. Conclusion SARS-COV-2 pandemic led to changes in the characteristics of dental emergency patients. Trauma, acute pulpitis, and acute periodontitis are the leading reasons patients refer to dental emergency centers. Dental emergency centers should optimize treatment procedures, optimize the staff, and reasonably allocate materials according to the changes to improve the on-site treatment capacity and provide adequate dental emergency care.


2016 ◽  
Vol 18 (3) ◽  
pp. 146-149
Author(s):  
Milan Halenka ◽  
Zdeněk Fryšák ◽  
David Karásek ◽  
Pavel Koranda ◽  
Iva Metelková

2021 ◽  
pp. 000313482110415
Author(s):  
Thomas S. Yamashita ◽  
Richard T. Rogers ◽  
Trenton R. Foster ◽  
Melanie L. Lyden ◽  
John C. Morris ◽  
...  

1993 ◽  
Vol 129 (5) ◽  
pp. 377-380 ◽  
Author(s):  
Steen Karstrup ◽  
Laszlo Hegedüs ◽  
Hans H Holm

Ultrasonically guided percutaneous injection of 96% ethanol into solitary parathyroid tumours in patients with primary hyperparathyroidism may be used as an alternative to surgery in selected patients. Contrary to surgical parathyroidectomy, the acute changes in parathyroid function following ultrasound-guided chemical parathyroidectomy have never been described. Seven consecutive and highly selected patients with primary hyperparathyroidism were treated with ultrasonically guided injection of ethanol (96%) into solitary and biopsy-verified parathyroid tumours. Basic treatment included a maximum of three injections separated by intervals of 24 h. In six of the seven patients normal serum values of ionized calcium were achieved within 36–120 h (median 36 h) and normal serum values of intact parathyroid hormone within 6–78 h (median 24 h). Three patients received two injections and three patients three injections. One patient remained hypercalcaemic in spite of three injections. Subsequent surgery showed the patient to have two parathyroid adenomas, of which only one had been detected ultrasonically. The present study has demonstrated a fast normalization of parathyroid function following two to three ethanol injections into solitary parathyroid tumours in selected patients with primary hyperparathyroidism.


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