scholarly journals Tratamento de disfunções temporomandibulares com toxina botulínica tipo A

2018 ◽  
Vol 23 (2) ◽  
Author(s):  
Geovana De Oliveira Polette Petrolli ◽  
Pamella Monteiro Mendes ◽  
Fernanda Angeloni De Souza ◽  
Matheus Coelho Blois

 Introdução: a disfunção temporomandibular (DTM) abrange muitos problemas clínicos nas articulações, na musculatura e em outras regiões da oroface. A ori­gem multifatorial e sua etiologia envolvem fatores psi­cocomportamentais, oclusais e neuromusculares, seu diagnóstico é realizado pela anamnese detalhada, com a identificação dos fatores predisponentes, iniciadores e perpetuantes, e pelo exame físico, que consiste em palpação da musculatura, mensuração da movimenta­ção ativa e verificação dos ruídos articulares. Objetivo: sistematizar as evidências científicas e verificar a eficá­cia do tratamento de disfunções temporomandibulares de origem muscular com a toxina botulínica do tipo A (TBX-A). Materiais e método: a busca bibliográfica foi realizada nas bases de dados PubMed e SciELO, com os descritores: “myofascial pain”, “botulinum toxin” e “masticatory muscles”. Foram analisados ensaios clíni­cos randomizados, que apresentaram tratamento para DTM com a utilização da TBX-A em pacientes de am­bos os sexos. A qualidade metodológica dos artigos se­lecionados foi verificada de acordo com a escala de Ja­dad. Considerações finais: observou-se que o tratamen­to para a DTM por meio da TBX-A auxilia no tratamento de dores orofaciais permanentes como coadjuvante, aliado a tratamentos conservadores. Os estudos que de­monstraram resultados clínicos significativos utilizaram uma dose total de 100 U de TBX-A, sendo 30 U nos músculos masseteres e 20 U nos músculos temporais, bilateralmente.

2018 ◽  
Vol 24 (3) ◽  
pp. 107-111 ◽  
Author(s):  
Alexis Kahn ◽  
Helios Bertin ◽  
Pierre Corre ◽  
Morgan Praud ◽  
Arnaud Paré ◽  
...  

Introduction: Temporomandibular disorders (TMD) are a common and invalidating disease sometimes difficult to treat. Current international recommendations favour reversible and non-invasive treatments, including the injection of botulinum toxin (BTX) into masticatory muscles. There is no strong evidence of its effectiveness. Objective: The main goal of this study was to assess the effectiveness of BTX six months following injection, in terms of pain, mouth opening, improvement of symptoms and duration of effect. Materials and methods: A retrospective study carried out at Nantes University Hospital between 2014 and 2016. Results: Thirty-four patients were included. The mean age was 37 years (17–76) and seventy six percents were female. Eighty percent of patients reported a significant improvement, notably in cases of arthralgia, which decreased in 8/18 (44%) patients (p < 0.05). The mean duration of measured efficacy was 4.2 months. Discussion: Significant improvement in cases of arthralgia and a tendency for improvement in cases of myalgia, with a mean duration of action of 4.2 months. Although BTX injection do not guarantee complete resolution of myofascial pain, it have been shown to have beneficial effects on some symptoms have been shown. Conclusion: Botulinum toxin should be considered as an alternative treatment when other conservative methods fail to yield satisfactory results. A thorough multicentre assessment is necessary in the future to scientifically validate its use.


2017 ◽  
Vol 28 (5) ◽  
pp. 493 ◽  
Author(s):  
Sagar Sewane ◽  
VarshaA Jadhao ◽  
Nitin Lokhande ◽  
ShwetaG Habbu ◽  
Shailesh Dongare ◽  
...  

2014 ◽  
Vol 21 (3) ◽  
Author(s):  
Maria Matilde de Mello Sposito ◽  
Stephanie Alderete Feres Teixeira

2021 ◽  
Vol 66 (3) ◽  
pp. 29-34
Author(s):  
A. Ilyin ◽  
T. Fazylova ◽  
A. Dergilev ◽  
A. Sudarkina ◽  
E. Olesov ◽  
...  

Purpose: Determination of the volume and sequence of radiation studies in the treatment of patients with displacement of the articular disc of the temporomandibular joint (TMJ)and myofascial pain disorders. Material and methods: The study included 48 patients with displacement of the articular disc of the TMJ and myofascial pain disorders. Clinical criteria for articular displacement were confirmed by MRI and CBCT. Studies of the function of the masticatory muscles were carried out at the Synapsis electromyograph. All patients underwent complex treatment, including relaxation of the masticatory muscles and relief of pain using injections of botulinum toxin in the actual masticatory, temporal and lateral pterygoid muscles (LPM), followed by repositioning split therapy. For the introduction of muscle relaxant in LPM, we have developed and applied external periarticular injection access to LPM. The method is based on reaching the zone of joint attachment of the upper and lower heads of the LPM with MRI navigation. Surveillance continued for up to 12 months with MRI monitoring of the position of the articular disc. Results: The stages of treatment of SJS of the TMJ with control use of MRI and CT, as well as a method for the administration of botulinum toxin under MRI navigation, have been developed. The first stage included CT and MRI of the temporomandibular joint, the second stage – injections of botulinum toxin into the masticatory muscles using the developed periarticular access to the LPM with MRI navigation, as well as CBCT with a splint to control the new (established) position of the lower jaw; the third and fourth stages included continuation of the reduction splint therapy, correction of the splint, observation for 3-6 months with control CBCT after 6 months to assess the position of the mandible without splint. Achieved an increase in the posterior and upper temporomandibular joint distances and the correct position of the lower jaw. Conclusion: Performing radiation studies on time at certain stages of treatment, differing in their content and volume, provided a complete diagnosis, planning treatment measures and monitoring the results.


Author(s):  
Marina I. Soykher ◽  
O. R Orlova ◽  
L. R Mingazova ◽  
M. G Soykher ◽  
A. A Mammedov

Treatment of diseases of the temporomandibular joint (TMJ), complicated by hypertension of the masticatory muscles, remains one of the unsolved problems of dentistry. The purpose of this clinical study is to assess the safety and efficacy of the first Russian botulinum toxin a (BTA) Relatox® for the correction of masticatory muscle hypertension in patients with myofascial pain syndrome, as well as its comparison with the Lantox® by these parameters. Injections of botulinum toxin type A are a method of treatment in patients with myofascial facial pain syndrome with high therapeutic potential. The analysis of clinical results of using the Russian botulinum toxin type A of Relatox® shows high clinical efficacy. Comparative analysis of Lantox® and Relatox® showed no differences in safety and efficacy.


2018 ◽  
Author(s):  
Dr Malathi Dayalan ◽  
Dr Sudeshna Sharma ◽  
Dr Shweta Poovani ◽  
Dr Saher Altaf

BACKGROUND Masticatory system is a complex functional unit, primarily engaged in chewing, swallowing and breathing functions, and some parts are involved in taste recognition and determination of food consistency. Sophisticated functional performances of speech and emotional expressions are specifically human qualities. Irregularities in occlusion appears to be the precipitating factor in the pathogenesis of myofascial pain dysfunction syndrome. Tek- Scan III records the bite length, number, distribution, timing, duration and the relative force of each tooth contact. It also records the sequence of occlusal contacts in terms of time and the associated force with each occlusal contact. The aim of this study was to treat masticatory muscle disorders with occlusal equilibration, and compare the efficacy of treatment outcomes between selective grinding and stabilization splints using Tek-Scan III. OBJECTIVE Objective of this study was to compare the efficacy of occlusal equilibration achieved through selective griding and stabilization splints using Tek-Scan III. METHODS In this in vivo study, 40 patients with masticatory muscle disorders were selected based on the inclusion and exclusion criteria. The occlusal discrepancies were analyzed using Tek-Scan III. The selected 40 subjects were then randomly divided into 2 groups based on the treatment they recieved; Group I – Selective grinding group (20) and Group II – Stabilization splint group (20). Comparison of pre-treatment and post treatment results were evaluated in terms of pain, mouth opening, left and right side force percentage as recorded through Tek-Scan III and reduction of disclusion time. Statistical analysis was carried out with Kolmogorov Smirnov test, Wilcoxon matched pair test and Mann-Whitney U test. RESULTS Wilcoxon matched pairs test demonstrated that there was statistically significant results ( p = 0.0007) in both the groups for reduction of disclusion time, elimination of pain and improved mouth opening. Patients in Group I showed better results as compared to Group II in terms of disclusion time, pain and mouth opening. CONCLUSIONS Occlusal equilibration brought about by reducing the disclusion time using the Tek- Scan III reduced the symptoms of pain in masticatory muscles. Patients in group I (Selective grinding) however showed better results when compared to patients in group II (Stabilization splints).


Author(s):  
Raffaele Rauso ◽  
Giorgio Lo Giudice ◽  
Gianpaolo Tartaro ◽  
Nicola Zerbinati ◽  
Giovanni Francesco Nicoletti ◽  
...  

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