Long-Term Outcome and Predictors ofSurvival in Patients Hospitalized For an Acute Exacerbation of Chronic Obstructive Pulmonary Disease

2010 ◽  
Vol 30 (3) ◽  
pp. 1046-1054 ◽  
Author(s):  
Elif ŞEN ◽  
Seda ÖZCAN ÇİLOĞLU ◽  
Zeynep ÖNEN ◽  
Banu GÜLBAY ◽  
Öznur AKKOCA YILDIZ ◽  
...  
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Acute Exacerbation ◽  
Chronic Obstructive ◽  
Term Outcome ◽  
Obstructive Pulmonary Disease ◽  
Long Term Outcome

Asymmetric Dimethylarginine Predicts Long-Term Outcome in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Lung ◽  
2017 ◽  
Vol 195 (6) ◽  
pp. 717-727 ◽  
Author(s):  
Alaadin Vögeli ◽  
Manuel Ottiger ◽  
Marc A. Meier ◽  
Christian Steuer ◽  
Luca Bernasconi ◽  
...  
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Acute Exacerbation ◽  
Asymmetric Dimethylarginine ◽  
Chronic Obstructive ◽  
Term Outcome ◽  
Obstructive Pulmonary Disease ◽  
Long Term Outcome

Impact of Chronic Obstructive Pulmonary Disease on Long-Term Outcome of Patients Hospitalized for Heart Failure

2008 ◽  
Vol 101 (3) ◽  
pp. 353-358 ◽  
Author(s):  
Dan Rusinaru ◽  
Imen Saaidi ◽  
Stephanie Godard ◽  
Haïfa Mahjoub ◽  
Caroline Battle ◽  
...  
Keyword(s):  
Heart Failure ◽  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Chronic Obstructive ◽  
Term Outcome ◽  
Obstructive Pulmonary Disease ◽  
Long Term Outcome

scholarly journals Hyperuricemia Is Not Predictive of Long-Term Outcome in Patients with Stable Chronic Obstructive Pulmonary Disease

2020 ◽  
Vol 35 (8) ◽  
Author(s):  
Jae-Joon Hwang ◽  
Yeon-Mok Oh ◽  
Chin Kook Rhee ◽  
Kwang Ha Yoo ◽  
Yong Bum Park ◽  
...  
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Chronic Obstructive ◽  
Term Outcome ◽  
Obstructive Pulmonary Disease ◽  
Long Term Outcome

scholarly journals Soluble ST2 and All-Cause Mortality in Patients with Chronic Obstructive Pulmonary Disease—A 10-Year Cohort Study

2021 ◽  
Vol 11 (1) ◽  
pp. 56
Author(s):  
Matthias H. Urban ◽  
Stefan Stojkovic ◽  
Svitlana Demyanets ◽  
Christian Hengstenberg ◽  
Arschang Valipour ◽  
...  
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Cohort Study ◽  
Pulmonary Disease ◽  
Forced Expiratory Volume ◽  
Chronic Obstructive ◽  
Term Outcome ◽  
Obstructive Pulmonary Disease ◽  
Long Term Outcome ◽  
All Cause Mortality

Chronic obstructive pulmonary disease (COPD) is an inflammatory condition with constantly increasing mortality rates. Interleukin (IL)-33 and its decoy receptor, soluble suppression of tumorigenicity 2 (sST2), play a central role in the inflammatory response during infection. sST2 was suggested as a factor in the pathogenesis of COPD and emerged as a predictor of mortality in other non-communicable diseases. The role of sST2 as a predictor of mortality remains unclear in COPD yet. In this cohort study, we measured circulating concentrations of IL-33 and sST2 in the serum of patients with stable COPD (n = 59), patients with acute exacerbation of COPD (n = 29) and smoking (n = 20) and non-smoking controls (n = 20), using commercially available ELISAs, and investigated the prognostic role of sST2 in stable COPD. sST2 levels were significantly higher in COPD patients and smokers compared with non-smoking controls. We identified systolic blood pressure, forced expiratory volume in 1 s (FEV1% predicted), neutrophil count, lactate dehydrogenase and pack-years index as independent predictors of sST2 levels. During a median follow-up time of 10.6 years, 28 patients (47.5%) died. sST2 was an independent predictor of all-cause mortality in patients with COPD with a hazard ratio of 2.9 (95% CI 1.1–8.4, p = 0.035) per one standard deviation after adjustment for age, sex, pack-years, FEV1% predicted and C-reactive protein (CRP). sST2 concentrations are associated with severity of disease and long-term outcome in patients with COPD.

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