scholarly journals Research Progress on Pharmacology and adverse reactions of hirudin

2021 ◽  
Vol 3 (3) ◽  
pp. 13
Author(s):  
YuQiang Lu ◽  
GuoCheng Zhang ◽  
Hui Ding ◽  
ZhaoLin Shi ◽  
RuYing Li
2021 ◽  
Vol 5 (4) ◽  
pp. 144-147
Author(s):  
Dan Zhang ◽  
Jing Cai ◽  
Xiaoping Cui ◽  
Xinchun Xiao

In recent years, the frequency of clinical occurrence of abnormal uterine bleeding in adolescence has gradually increased. In order to fully understand the research progress in the treatment of abnormal uterine bleeding in adolescence, various studies and clinical experience have been reviewed by consulting related literature reports. The results found that currently Western medicine mainly uses hormone drugs in clinical treatment, but there are risks such as more clinical adverse reactions and higher recurrence rate; traditional Chinese medicine (TCM) treatment has achieved satisfactory results, but the advantages of sudden collapse and hemostasis are not obvious. Combined TCM and Western medicine treatment, it can learn from each other and has become a research hotspot in recent years, which is worthy of an in-depth discussion.


2021 ◽  
Vol 5 (4) ◽  
pp. 1-7
Author(s):  
Zhuli Hou ◽  
Gang Fang

Abstract: The continuous increase in the incidence rate of various fatal malignant tumors in the recent years warrants an imperative search for medications or drugs with obvious anti-tumor effects and reliable curative effects. Previous studies have found that Curcuma zedoaria and its active ingredients, such as turmeric oil, curcumol, and ?-elemene, have obvious anti-tumor effects, and they do not have the adverse reactions and side effects seen in the anti-tumor drugs of Western medicine. Based on the review and inductive analysis of related literature, we summarize in the present article the results of some researchers who investigated the anti-tumor effects of Curcuma zedoaria and its active ingredients through the immune regulation mechanism.


2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Sicong Li ◽  
Fang Liu ◽  
Kai Zhang ◽  
Yujia Tong ◽  
Xin Liu

As the spectrum of ophthalmic diseases keeps changing, uveitis has gradually become one of the major blinding eye diseases in the world. Although the efficacy and safety of adalimumab and other biological agents in the treatment of uveitis have been proved in clinical studies, no biological agents have been approved for the treatment of uveitis by Chinese National Medical Products Administration (NMPA). The quality of life and prognosis of uveitis patients are affected by the adverse reactions of currently available immunosuppressive drugs. In recent years, it has become a research hotspot to select effective components for uveitis treatment from natural drugs. Based on the classification of chemical structure, the therapeutic effect and mechanism of natural drug components on uveitis were discussed in detail, in order to provide reference for basic drug development and clinical research.


2010 ◽  
Vol 44 (6) ◽  
pp. 10-11
Author(s):  
JENNIE SMITH
Keyword(s):  

2007 ◽  
Vol 40 (7) ◽  
pp. 18-19
Author(s):  
ELIZABETH MECHCATIE
Keyword(s):  

2015 ◽  
Vol 20 (3) ◽  
pp. 155-166 ◽  
Author(s):  
Larissa J. Maier ◽  
Michael P. Schaub

Abstract. Pharmacological neuroenhancement, defined as the misuse of prescription drugs, illicit drugs, or alcohol for the purpose of enhancing cognition, mood, or prosocial behavior, is not widespread in Europe – nevertheless, it does occur. Thus far, no drug has been proven as safe and effective for cognitive enhancement in otherwise healthy individuals. European studies have investigated the misuse of prescription and illicit stimulants to increase cognitive performance as well as the use of tranquilizers, alcohol, and cannabis to cope with stress related to work or education. Young people in educational settings report pharmacological neuroenhancement more frequently than those in other settings. Although the regular use of drugs for neuroenhancement is not common in Europe, the irregular and low-dose usage of neuroenhancers might cause adverse reactions. Previous studies have revealed that obtaining adequate amounts of sleep and using successful learning techniques effectively improve mental performance, whereas pharmacological neuroenhancement is associated with ambiguous effects. Therefore, non-substance-related alternatives should be promoted to cope with stressful situations. This paper reviews the recent research on pharmacological neuroenhancement in Europe, develops a clear definition of the substances used, and formulates recommendations for practitioners regarding how to react to requests for neuroenhancement drug prescriptions. We conclude that monitoring the future development of pharmacological neuroenhancement in Europe is important to provide effective preventive measures when required. Furthermore, substance use to cope with stress related to work or education should be studied in depth because it is likely more prevalent and dangerous than direct neuroenhancement.


2019 ◽  
Vol 227 (1) ◽  
pp. 64-82 ◽  
Author(s):  
Martin Voracek ◽  
Michael Kossmeier ◽  
Ulrich S. Tran

Abstract. Which data to analyze, and how, are fundamental questions of all empirical research. As there are always numerous flexibilities in data-analytic decisions (a “garden of forking paths”), this poses perennial problems to all empirical research. Specification-curve analysis and multiverse analysis have recently been proposed as solutions to these issues. Building on the structural analogies between primary data analysis and meta-analysis, we transform and adapt these approaches to the meta-analytic level, in tandem with combinatorial meta-analysis. We explain the rationale of this idea, suggest descriptive and inferential statistical procedures, as well as graphical displays, provide code for meta-analytic practitioners to generate and use these, and present a fully worked real example from digit ratio (2D:4D) research, totaling 1,592 meta-analytic specifications. Specification-curve and multiverse meta-analysis holds promise to resolve conflicting meta-analyses, contested evidence, controversial empirical literatures, and polarized research, and to mitigate the associated detrimental effects of these phenomena on research progress.


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