AN OVERVIEW OF THE GLOBAL OUTBREAK OF CORONAVIRUS DISEASE (COVID-19) INCLUDING THE ROLE OF VITAMIN D AND BEST POSSIBLE MANAGEMENT IN THE LIGHT OF UNANI MEDICINES : A REVIEW

2020 ◽  
Vol 13 (1) ◽  
Author(s):  
Rabia Khan ◽  
Yasmeen Shamsi ◽  
Khursheed Ahmed Ansari ◽  
Amreen Amreen ◽  
Araf Fatima ◽  
...  
Keyword(s):  
Vitamin D ◽  
Respiratory Tract Infections ◽  
Vitamin D Supplementation ◽  
Research Progress ◽  
Vitamin D Levels ◽  
Reduce Risk ◽  
The One ◽  
Tract Infections ◽  
Pro Inflammatory Cytokines

Objective: The aim of this review was to assess the roles of vitamin D in reducing the risk of respiratory tract infections, knowledge about the epidemiology of influenza and COVID-19, and how vitamin D supplementation might be a useful measure to reduce risk and also to outline the research progress and literature available of the epidemiology, pathogenesis, and clinical characteristics of COVID-19 patients information regarding the ongoing pandemic.Unani medicines can play significant role as adjuvent therapy to control the adverse effect of COVID-19 and can also act asa a best Immunomodulator. Methods: Aliterature search was conducted using the databases PubMed, Medline, Scopus and Web of Science. We described overall possible association between COVID-19 and Vitamin D. We have searched by the names corona virus, covid-19 and vitamin D association with COVID-19. Result: Through several mechanisms, vitamin D can reduce the risk of infections by lowering viral rates of replication and also reducing concentrations of pro-inflammatory cytokines that are responsible for the inflammation and injuries in the pleura. Conclusion: It was additionally observed that COVID-19 and vitamin D have a crude substantial relationship and specifically the mortality induced through this infection. The most susceptible crew of the populace for COVID-19, the getting old population, is additionally the one that has the most deficit Vitamin D levels.

STUDY OF VITAMIN D LEVELS IN CHILDREN WITH LOWER RESPIRATORY TRACT INFECTION AT CRGH AND ASSOCIATED HOSPITALS OF R.D. GARDI MEDICAL COLLEGE

2021 ◽  
pp. 57-59
Author(s):  
Nency Sahu ◽  
Mamta Dhaneria
Keyword(s):  
Vitamin D ◽  
Respiratory Tract ◽  
Lower Respiratory Tract ◽  
Respiratory Tract Infections ◽  
Vitamin D Supplementation ◽  
Study Data ◽  
Lower Respiratory Tract Infections ◽  
Increased Risk ◽  
Vitamin D Levels ◽  
Tract Infections

Background: Lower Respiratory tract infections (LRTIs) remain among the most important causes of morbidity and mortality among children. Several studies have associated vitamin D deciency with an increased risk of LRTIs. The main objective of this study is to assess the prevalence of vitamin D deciency in children from 6 months to 5 years of age with LRTI, and to evaluate the correlation between vitamin D levels and the incidence and severity of LRTI. A hospital based Material and Methods: observational study was carried out in the patients admitted for LRTI in pediatric ward of CR Gardi hospital of RDGMC from October 2018 to July 2020. A total of 70 children were included between the age group 6 months to 5 years were selected for the study. Data were entered in MS excel and analyzed by software Stata 10. Vitamin D levels were divided Results: into three categories, decient, insufcient, and sufcient. Average Vitamin D levels were 25.98ng/dl. Out of 70 children with lower respiratory tract infections 28.57% (n=20) children, had decient levels (<20ng/ml) of vitamin D, 38.57% (n=27) had insufcient levels (21-29ng/ml), while 32.86% (n=23) patients had sufcient (>30ng/ml) vitamin D levels. Vitamin D levels are found to be decient in 39% cases of LRTI, However Conclusion: 26% children had Vitamin D levels in a decient range. Since 65% of children with LRTI had either decient or insufcient levels of Vitamin D. Vitamin D should be estimated in all children with LRTI. In places where Vitamin D levels cannot be estimated Vitamin D supplementation should be given. There is a need of more studies to be done on a larger sample size to reach to a certain conclusion.

Vitamin D deficiency and lower respiratory tract infections in children: a systematic review and meta-analysis of observational studies

2016 ◽  
Vol 47 (1) ◽  
pp. 77-84 ◽  
Author(s):  
Kana Ram Jat
Keyword(s):  
Systematic Review ◽  
Vitamin D ◽  
Respiratory Tract ◽  
Vitamin D Deficiency ◽  
Lower Respiratory Tract ◽  
Respiratory Tract Infections ◽  
Vitamin D Supplementation ◽  
Lower Respiratory Tract Infections ◽  
Vitamin D Levels ◽  
Tract Infections

Studies related to vitamin D deficiency and lower respiratory tract infections (LRTI) in children have inconsistent findings. The objective of this systematic review was to assess the prevalence of vitamin D deficiency in children with LRTI, and to evaluate the correlation between vitamin D levels and the incidence and severity of LRTI. A total of 12 studies enrolling 2279 participants were included in our analysis. Children with LRTI were found to have significantly lower mean vitamin D levels as compared to controls There was likewise a correlation between vitamin D levels and incidence and severity of LRTI. Large randomised controlled trials are needed to evaluate effect of vitamin D supplementation for LRTI.

scholarly journals Does vitamin D supplementation prevent SARS-CoV-2 infection in military personnel? Review of the evidence

2021 ◽  
pp. bmjmilitary-2020-001686
Author(s):  
Iain T Parsons ◽  
R M Gifford ◽  
M J Stacey ◽  
L E Lamb ◽  
M K O'Shea ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Supplementation ◽  
Vitamin D Status ◽  
Military Studies ◽  
Vitamin D Receptors ◽  
Area Of Interest ◽  
Military Populations ◽  
Tract Infections ◽  
Recruit Training

For most individuals residing in Northwestern Europe, maintaining replete vitamin D status throughout the year is unlikely without vitamin D supplementation and deficiency remains common. Military studies have investigated the association with vitamin D status, and subsequent supplementation, with the risk of stress fractures particularly during recruit training. The expression of nuclear vitamin D receptors and vitamin D metabolic enzymes in immune cells additionally provides a rationale for the potential role of vitamin D in maintaining immune homeostasis. One particular area of interest has been in the prevention of acute respiratory tract infections (ARTIs). The aims of this review were to consider the evidence of vitamin D supplementation in military populations in the prevention of ARTIs, including SARS-CoV-2 infection and consequent COVID-19 illness. The occupational/organisational importance of reducing transmission of SARS-CoV-2, especially where infected young adults may be asymptomatic, presymptomatic or paucisymptomatic, is also discussed.

scholarly journals Role of Vitamin D in Reducing the Frequency of Asthma Attacks in Patients with Frequent Exacerbation of Asthma

2021 ◽  
pp. 11-16
Author(s):  
Mubeen Ahmed Memon ◽  
Sheeba Faryal Ansari ◽  
Mumtaz Ali Lakho ◽  
Mukhtiar Hussain Jaffery ◽  
Syed Zulfiquar Ali Shah ◽  
...  
Keyword(s):  
Vitamin D ◽  
Corticosteroid Treatment ◽  
Vitamin D Supplementation ◽  
The Body ◽  
P Value ◽  
Care Hospital ◽  
Asthma Exacerbations ◽  
Vitamin D Levels ◽  
Interventional Group

Introduction: Vitamin D deficiency is common among asthmatics with literature suggesting that its low levels in the body may trigger exacerbations and decrease the response to corticosteroid treatment. It has also shown to inhibit the production of cytokines, which in turn enhances the body’s response to corticosteroid treatment during an exacerbation. Therefore, maintenance of adequate levels of vitamin D in patients with asthma may reduce the risk of exacerbation and improve their general health. This study aims to explore the role of vitamin D supplementation in preventing asthma exacerbations. Methods: This single blind parallel arm interventional study was conducted in the pulmonology ward in a tertiary care hospital from June 2018 to April 2020. Two hundred (n= 200) participants with a history of frequent acute exacerbation of asthma were enrolled in the study via consecutive convenient non-probability technique. Participants were divided into two groups; the placebo and the interventional group that received 200,000 IU of vitamin D capsule. Results: Compared to day 0, mean episodes of exacerbation in the interventional group were significantly lower after 180 days (1.1 ± 0.4 vs. 0.61 ± 0.3; p-value <0.0001). Similarly, number of asthma attacks in past 7 days was significantly lower in intervention group after 180 days (4.4 ± 2.7 vs. 3.1 ± 1.5; p-value 0.0001) Conclusion: Vitamin D supplementation is a safe and cost-friendly approach to reducing asthma exacerbations. It may also help to improve the condition in severe asthmatics with low vitamin D levels.

Weniger akute Atemwegsinfekte durch Vitamin-D-Supplementation?

2018 ◽  
Vol 97 (08) ◽  
pp. 524-525
Author(s):  
Klaus Weckbecker
Keyword(s):  
Systematic Review ◽  
Vitamin D ◽  
Respiratory Tract Infections ◽  
Meta Analysis ◽  
Vitamin D Supplementation ◽  
Individual Participant Data ◽  
Individual Participant ◽  
25 Hydroxy Vitamin D ◽  
25 Oh Vitamin D ◽  
Tract Infections

Martineau AR. et al. Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data. BMJ 2017; 356: i6583 Vitamin D spielt Studien zufolge auch eine Rolle bei der Abwehr pathogener Keime: 25-Hydroxy-Vitamin D (25[OH] Vitamin D) unterstützt z. B. die Synthese antimikrobieller Peptide. Es gibt also eine mögliche Erklärung für die Beobachtung, dass Personen mit niedrigen Vitamin-D-Spiegeln besonders empfindlich gegenüber respiratorischen Infekten sind. Untersuchungen zu einer präventiven Wirkung des Vitamin D verliefen jedoch zum Teil widersprüchlich.

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