scholarly journals Usefulness of99mTc-HDP scintigraphy in the diagnosis of suspected cardiac amyloidosis revealed by heart failure: A case report of an amyloidogenic transthyretin mutation and literature review

2015 ◽  
Vol 6 (9) ◽  
pp. 596
Author(s):  
Geraldine Celine Bera ◽  
Lavinia Vija ◽  
Pierre Jean Fouret ◽  
Nathanaëlle Yeni
Keyword(s):  
Heart Failure ◽  
Case Report ◽  
Literature Review ◽  
Cardiac Amyloidosis

scholarly journals Cardiac Amyloidosis Wild Type (ATTR-CAwt) and Associated Cardiac Arrhythmias: A Case Report and Literature Review

2021 ◽  
pp. 263246362199858
Author(s):  
Rangadham Nagarakanti ◽  
Kesavan Sankaramangalam ◽  
Sindhu Nagarakanti ◽  
Danyaal Moin ◽  
Kenneth Dulnuan ◽  
...  
Keyword(s):  
Heart Failure ◽  
Case Report ◽  
Mortality Rate ◽  
Literature Review ◽  
Ejection Fraction ◽  
Cardiac Arrhythmias ◽  
Cardiac Amyloidosis ◽  
Clinical Signs ◽  
Preserved Ejection Fraction ◽  
Wild Type

Cardiac amyloidosis wild type (ATTR-CAwt) is often the underdiagnosed cause of heart failure with preserved ejection fraction (HFpEF) and has a high mortality rate. There is usually a long delay between the appearance of clinical signs and the diagnosis of ATTR-CAwt but a short duration between diagnosis and death. ATTR-CAwt was associated with significant clinical arrhythmias. We report a case of ATTR-CAwt, the process of its diagnosis, and the associated clinical arrhythmias and their management. We also reviewed the literature of this underdiagnosed and potentially fatal condition and the current existing therapies.

scholarly journals Concurrent End-Stage Cardiomyopathy and Aortic Disease in Patients with Marfan Syndrome: A Case Report and Literature Review

2021 ◽  
Author(s):  
Timothy Smith ◽  
Jose Sleiman ◽  
Nikita Zadneulitca ◽  
Cedric Sheffield ◽  
Viviana Navas ◽  
...  
Keyword(s):  
Heart Failure ◽  
Case Report ◽  
Literature Review ◽  
Marfan Syndrome ◽  
Aortic Disease ◽  
Connective Tissue Disorder ◽  
Orthotopic Heart Transplantation ◽  
Bentall Procedure ◽  
Life Saving ◽  
End Stage

Abstract Background: Marfan syndrome (MFS) is a connective tissue disorder that can lead to aortic disease, arrhythmias and heart failure. Many centers are reluctant to offer orthotopic heart transplantation (OHT) for patients with MFS with concurrent aortic disease due to complexity of the surgery and perceived inferior results when compared to patients without MFS. Methods: We present a case of a patient with MFS with previous Bentall procedure who underwent successful OHT, accompanied by a literature review on OHT performed for patients with MFS. Results and Conclusions: Patients with MFS who underwent OHT had no difference in mortality compared to patients without MFS. Even though OHT is technically more challenging when combined with concurrent intervention for aortic disease, it should be considered as a life-saving operation for patients with MFS.

High-dose adenosine for refractory supraventricular tachycardia: a case report and literature review

2016 ◽  
Vol 27 (5) ◽  
pp. 981-984 ◽  
Author(s):  
Gal Dadi ◽  
Daniel Fink ◽  
Giora Weiser
Keyword(s):  
Heart Failure ◽  
Case Report ◽  
Literature Review ◽  
Cardiogenic Shock ◽  
Sinus Rhythm ◽  
Supraventricular Tachycardia ◽  
Electrical Cardioversion ◽  
High Dose ◽  
Prompt Treatment ◽  
Unstable Patient

AbstractSupraventricular tachycardia is the most common significant arrhythmia in children. If prolonged, it may cause heart failure and progress to cardiogenic shock warranting prompt treatment. The recommended interventions following vagal manoeuvres are intravenous adenosine and in the unstable patient electrical cardioversion. We present an infant with an unstable supraventricular tachycardia that was resistant to electrical cardioversion and recommended doses of adenosine. He reverted to sinus rhythm with a higher dose of adenosine, suggesting that such doses may be required in refractory supraventricular tachycardia.

scholarly journals A Case Report of Cardiac Amyloidosis Highlighting the Importance of Strain Analysis

2021 ◽  
Vol 2021 ◽  
pp. 1-5
Author(s):  
Andres Cordova Sanchez ◽  
Ryan Murphy ◽  
Suman Rao ◽  
Fidel Martinez ◽  
Stephanie Bryant ◽  
...  
Keyword(s):  
Heart Failure ◽  
Case Report ◽  
High Mortality ◽  
Light Chain ◽  
Cardiac Amyloidosis ◽  
Inverse Relationship ◽  
Cardiac Involvement ◽  
Strain Analysis ◽  
Al Amyloidosis ◽  
Cardiac Symptoms

Cardiac involvement in light-chain (AL) amyloidosis has a high mortality. Once cardiac symptoms are present, it is important to make a diagnosis as there is an inverse relationship between mortality and time of diagnosis. Echocardiography is usually one of the first tests performed. But strain analysis, which can provide important clues, is not routinely performed. This is a case of AL amyloidosis presenting with heart failure in which echocardiographic strain analysis was vital for its diagnosis.

Diagnosis of Cardiac Transthyretin Amyloidosis by Technetium-99m Pyrophosphate Heart Scan, Confirmed by Genetic Mutations: Case Report

2021 ◽  
Vol 104 (11) ◽  
pp. 1843-1846
Keyword(s):  
Heart Failure ◽  
Case Report ◽  
Genetic Testing ◽  
Cardiac Amyloidosis ◽  
Abdominal Fat ◽  
Genetic Mutations ◽  
Fat Pad ◽  
Transthyretin Amyloidosis ◽  
Technetium 99M ◽  
Clinically Significant

Amyloid deposition in the myocardium can cause clinically significant heart failure, which is very difficult to diagnose. The present case reported presented a patient with heart failure, with suspected cause of cardiac amyloidosis, but abdominal fat pad and endomyocardial with Congo red stain biopsies were negative. Due to high suspicion of cardiac amyloidosis, a technetium-99m pyrophosphate (Tc-99m PYP) heart scan was done, which was revealed as strongly suggestive for cardiac transthyretin amyloidosis. So, the patient was sent for genetic testing, and a TTR gene mutation [c.148G>A (p.Val50Met)] was found. Keywords: Cardiac amyloidosis; Endomyocardial biopsy (EMB); Technetium-99m pyrophosphate (Tc-99m PYP) heart scan; Transthyretin amyloidosis (TTR)

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