scholarly journals A Case of Primary Tubercular Mastitis Masquerading as Carcinoma Breast

2011 ◽  
Vol 2011 ◽  
pp. 1-2
Author(s):  
Sameer Singhal
Keyword(s):  
Extrapulmonary Tuberculosis ◽  
Excisional Biopsy ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
True Nature ◽  
Potential Case ◽  
Surgical Options ◽  
Needle Aspiration Cytology ◽  
Important Position ◽  
High Index Of Suspicion

Primary extrapulmonary tuberculosis occurring in the breast is extremely rare. In the absence of well-defined clinical features, the true nature of the disease remains obscure and it is often mistaken for carcinoma or pyogenic breast abscess. It also presents a diagnostic problem on radiological and microbiological investigations and thus high index of suspicion acquires an important position. This paper highlights the importance of considering every breast lump as a potential case of tubercular mastitis especially in endemic countries like India that should be subjected to fine needle aspiration cytology or excisional biopsy before considering surgical options like complete mastectomy, without relying only on clinicoradiological findings.

scholarly journals Tubercular mastitis: An institutional experience from a tertiary care centre of northern India

2017 ◽  
Vol 8 (3) ◽  
pp. 72-75
Author(s):  
Amit Gupta ◽  
Lovenish Bains ◽  
Deepshikha Yadav ◽  
Prashant Durgapal ◽  
Manish Kumar Agrawal
Keyword(s):  
Tertiary Care ◽  
Needle Aspiration ◽  
Care Centre ◽  
Medical Sciences ◽  
Tertiary Care Centre ◽  
Aspiration Cytology ◽  
Northern India ◽  
Institutional Experience ◽  
Needle Aspiration Cytology ◽  
High Index Of Suspicion

Background: Tuberculous mastitis (TM) is a rare extra pulmonary presentation of tuberculosis. It may be problematic to distinguish from carcinoma breast, a condition with which it may coexist.  Fine needle aspiration cytology (FNAC) / biopsy are indispensable for diagnosis and tuberculosis culture when positive may be very valuable to guide antimicrobial therapy.Aims and Objectives:  To disseminate the message to the concerned expertise that it can present a diagnostic problem on radiological and microbiological investigations, and thus a high index of suspicion is needed.Materials and Methods: 19 cases of tubercular mastitis between  January 2012 to March 2014 were identified and included in the present study. Cytology and biopsy alongwith AFB stain was done for confirmation.Results: Age ranged between 23- 55 years (median 33 years). Axillary nodes were palpable in 9 (47.3%) patients. Acid Fast Bacilli stain which was positive in only 3 patients. All the 19 patients were started on antitubercular treatment.Conclusion: This study highlights the importance of early diagnosis and aggressive medical and if required surgical management to cure this disease.Asian Journal of Medical Sciences Vol.8(3) 2017 72-75

Cervical lymphadenopathy: scrofula revisited

2008 ◽  
Vol 123 (7) ◽  
pp. 764-767 ◽  
Author(s):  
R Khan ◽  
S H Harris ◽  
A K Verma ◽  
A Syed
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Extrapulmonary Tuberculosis ◽  
Cervical Lymphadenopathy ◽  
Polymerase Chain Reaction Analysis ◽  
Needle Aspiration ◽  
Cervical Lymphadenitis ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology

AbstractBackground:The commonest form of extrapulmonary tuberculosis is tubercular cervical lymphadenitis, or scrofula.Methods and results:A total of 1827 patients with cervical lymphadenopathy who presented to various out-patients clinics of our institution were studied over a three-year period. Eight hundred and ninety-three (48.87 per cent) of these patients had lesions of tubercular origin. The most common observation was unilateral, matted adenopathy in female patients aged between 11 and 20 years and without constitutional symptoms of tuberculosis. Posterior triangle nodes were affected in 43.8 per cent of cases, followed by upper deep cervical nodes in 33.9 per cent. Fine needle aspiration cytology constituted the main diagnostic tool, with a positive yield in 90 per cent of patients. Polymerase chain reaction analysis was performed in 126 patients, with a sensitivity of 63 per cent. Only 18 per cent of patients had associated pulmonary tuberculosis, the rest having isolated involvement of cervical nodes. Medical treatment with anti-tubercular drugs for a period of six months formed the mainstay of treatment and cure. Surgical management was reserved for selected refractory patients.Conclusion:Tubercular cervical lymphadenitis can readily be diagnosed by fine needle aspiration cytology, a simple and cost-effective test. The disease can be cured completely by a short course of anti-tubercular chemotherapy, without surgical intervention.

scholarly journals Calcifying epithelioma of Malherbe of cheek: a diagnostic challenge

2015 ◽  
Vol 1 (1) ◽  
pp. 96
Author(s):  
Ameya Bihani ◽  
Yogesh Dokhe ◽  
Priyanka Hardikar ◽  
Jyoti Dabholkar
Keyword(s):  
Imaging Technique ◽  
Excisional Biopsy ◽  
Needle Aspiration ◽  
Radiological Imaging ◽  
Diagnostic Challenge ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology ◽  
Rare Benign Tumour ◽  
Cheek Swelling

<p class="abstract">Malherbe’s calcifying epithelioma is a very rare benign tumour in area of cheek but generally present in first two decades of life. Fine Needle Aspiration Cytology (FNAC) and radiological imaging technique are not of great help in diagnosing this tumour. We hereby present a case of 15 year female with cheek swelling since 3 years which turned out to be pilomatricoma on histopathology of specimen of excisional biopsy. </p><p class="keywords"><strong><span lang="EN-US">Keywords: </span></strong>Malherbe’s calcifying epithelioma, Pilomatrixoma, BCL-2, CTNNB1</p>

scholarly journals Tuberculous Mastitis: Experience of Five Cases at a Tertiary Care Hospital

2016 ◽  
Vol 4 (2) ◽  
pp. 67-70
Author(s):  
Md Hasanuzzaman ◽  
Md Johirul Islam ◽  
AZM Mostaque Hossain ◽  
Mohammad Zillur Rahman ◽  
Md Ashraf Ul Haque ◽  
...  
Keyword(s):  
Tertiary Care ◽  
Surgical Oncology ◽  
Needle Aspiration ◽  
Care Hospital ◽  
Aspiration Cytology ◽  
Antitubercular Drugs ◽  
Granulomatous Lesions ◽  
Needle Aspiration Cytology ◽  
Breast Lumps ◽  
High Index Of Suspicion

Background: Tuberculous Mastitis (TM) is a rare form of tuberculosis, even in countries where the burden of tuberculosis is high. It may mimic other systemic illness, even carcinoma breast, a condition with which it may coexist.Objective: To disseminate the message to the concerned expertise that it can present a diagnostic problem on radiological and microbiological investigations, and thus a high index of suspicion is needed.Materials and method: This observational study was carried out in the department of Surgical Oncology of National Institute of Cancer Research & Hospital (NICRH), Dhaka, Bangladesh from January 2010 to December 2015. During the study period only five cases of TM were identified and all were included in the analysis purposively.Results: Mean(±SD) age of the patients was 27.2(±16.22) years. AFB in pus was found in one patient. Fine Needle Aspiration Cytology (FNAC) was done in four AFB negative patients and granulomatous lesions were found in each case. Histopathological examinations of two resected breast lumps also showed granulomatous lesions consistent with tuberculosis. Breast ultrasound showed multilocular abscess with ill-defined lump in two cases, solitary lump in two patients and cystic lesion in one patient. Axillary lymphadenopathy was found in one patient with solitary lump. Repeated image guided aspiration of the abscess was performed in 3 cases. Two patients underwent lumpectomy operation. All five patients were given anti-TB chemotherapy for 6 months. All of them recovered fully after completion of Category I treatment.Conclusion: Though it is a great mimicker with proper evaluation the disease is curable with antitubercular drugs, and in some cases surgery is required.Delta Med Col J. Jul 2016 4(2): 67-70

Incidence of malignancy in solitary thyroid nodules

2015 ◽  
Vol 129 (7) ◽  
pp. 677-681 ◽  
Author(s):  
S M Keh ◽  
S K El-Shunnar ◽  
T Palmer ◽  
S F Ahsan
Keyword(s):  
Thyroid Surgery ◽  
High Probability ◽  
Thyroid Nodules ◽  
Needle Aspiration ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Malignancy Rate ◽  
The Mean ◽  
Needle Aspiration Cytology ◽  
High Index Of Suspicion

AbstractObjectives:This study aimed to investigate the prevalence and clinical significance of solitary thyroid nodules in patients who underwent thyroid surgery.Methods:A retrospective review was performed of the case notes of all adult patients who underwent thyroid surgery from January 2003 to December 2009. All patients with solitary thyroid nodules identified by ultrasonography were included.Results:In total, 225 patients underwent thyroid surgery. The prevalence of solitary thyroid nodules was 27.1 per cent (61 out of 225 patients). Seventy-two per cent of patients were women and the mean age at presentation was 52 ± 16 years. In all, 75.4 per cent of solitary nodules had neoplastic pathology and the malignancy rate was 34.4 per cent. The sensitivity and specificity of fine needle aspiration cytology for neoplasm detection were 73.9 per cent and 80.0 per cent, respectively. There was no association between the various ultrasonography parameters and malignancy risk (p > 0.05).Conclusion:Solitary thyroid nodules should be investigated thoroughly with a high index of suspicion because there is a high probability (34.0 per cent) of malignancy.

Extracranial cysticercosis of the parotid gland: a case report with a review of the literature

2007 ◽  
Vol 122 (9) ◽  
pp. 1008-1011 ◽  
Author(s):  
G Veena ◽  
G M Shon ◽  
K Usha ◽  
R C Nayar
Keyword(s):  
Case Report ◽  
Parotid Gland ◽  
Relevant Literature ◽  
Needle Aspiration ◽  
Young Female ◽  
Diagnostic Methods ◽  
Review Of The Literature ◽  
Aspiration Cytology ◽  
Needle Aspiration Cytology ◽  
High Index Of Suspicion

AbstractObjective:A case of solitary extracranial cysticercosis of the parotid gland is reported. A discussion concerning the clinical features, imaging modalities, diagnostic methods and management of cysticercosis, along with a review of relevant literature is also presented.Case report:A young female patient presented with features resembling acute parotitis. Solitary cysticercosis of the parotid gland was diagnosed, based on fine needle aspiration cytology and radiological investigations. Medical therapy was effective, consequently surgery was deferred.Conclusion:This is the first report of solitary extracranial cysticercosis of the parotid gland. A high index of suspicion for such parasitic infestations is essential even in non-endemic areas due to the ease of worldwide travel.

Cervical tuberculous lymphadenitis in the elderly: comparative diagnostic findings

2009 ◽  
Vol 123 (12) ◽  
pp. 1343-1347 ◽  
Author(s):  
T Kato ◽  
Y Kimura ◽  
M Sawabe ◽  
Y Masuda ◽  
K Kitamura
Keyword(s):  
Malignant Lymphoma ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Cytology ◽  
Excisional Biopsy ◽  
The Elderly ◽  
Needle Aspiration ◽  
Tuberculous Lymphadenitis ◽  
Aspiration Cytology ◽  
Fine Needle ◽  
Needle Aspiration Cytology

AbstractBackground:Patients suspected of having cervical tuberculous lymphadenitis are diagnosed using investigations such as fine needle aspiration cytology and the polymerase chain reaction for Mycobacterium tuberculosis. However, these investigations are intended for primary tuberculosis infection. The majority of cervical tuberculous lymphadenitis cases in the elderly are thought to be caused by reactivation.Objective:The aims of this study were (1) to examine the efficacy of fine needle aspiration cytology, polymerase chain reaction and blood tests in the diagnosis of cervical tuberculous lymphadenitis caused by reactivation, and (2) to clarify any differences when compared with primarily infected cervical tuberculous lymphadenitis cases.Materials and methods:Thirty-three elderly patients with neck lumps underwent excisional biopsy from 2003 to 2008. The efficacy of fine needle aspiration cytology was examined by comparing the results of excisional biopsy with those of fine needle aspiration cytology performed at the initial medical examination for cases of suspected tuberculous disease. Furthermore, the leucocyte count and C-reactive protein concentration were compared for cases of cervical tuberculous lymphadenitis versus cases of malignant lymphoma.Results:Although nine cases were diagnosed with cervical tuberculous lymphadenitis using excisional biopsy, only one of these had been suspected based on fine needle aspiration cytology results. Three cases with tuberculous lymphadenitis were suspected of having malignant lymphoma on initial examination. There was no significant difference in the leucocyte count and C-reactive protein concentration, comparing cases of tuberculous lymphadenitis versus malignant lymphoma.Conclusion:Unlike the primary infection often seen in endemic areas, the diagnosis of early stage tuberculous lymphadenitis of the swelling type caused by reactivation in elderly people is difficult to confirm unless excisional biopsy is performed. In elderly patients with neck lumps, cervical tuberculous lymphadenitis should be included in the differential diagnosis.

scholarly journals Diagnostic challenges of tubercular lesions of breast

2018 ◽  
Vol 10 (02) ◽  
pp. 179-184 ◽  
Author(s):  
Zeeba Shamim Jairajpuri ◽  
Sujata Jetley ◽  
Safia Rana ◽  
Shaan Khetrapal ◽  
Sabina Khan ◽  
...  
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Needle Aspiration ◽  
Care Hospital ◽  
Epithelioid Cells ◽  
Aspiration Cytology ◽  
Rare Presentation ◽  
Breast Masses ◽  
Needle Aspiration Cytology ◽  
High Index Of Suspicion

ABSTRACT INTRODUCTION: Tuberculosis (TB) in the developing countries presents with both pulmonary and extrapulmonary manifestations. Breast TB, however, remains a rare presentation. Its importance lies in the fact that it may mimic malignancy or present as inflammatory lump/abscess. AIMS AND OBJECTIVE: The aim of the present study is to highlight the importance of breast TB and its diagnostic challenges. MATERIALS AND METHODS: It was a retrospective study conducted at a tertiary care hospital, over 2 years between 2013 and 2015 during which eight cases of breast lesions were diagnosed as of tubercular origin. RESULTS: Granulomas were seen in five cases while three cases revealed only few epithelioid cells, and necrosis was seen in all cases on fine-needle aspiration cytology. Histopathological evaluation was available in six out of the eight cases, while acid–fast bacilli were positive in three cases, the characteristic granulomas were seen in all the six cases evaluated. CONCLUSION: Significance of TB breast lies in the fact that it may masquerade as breast malignancy or pyogenic abscess. India is a developing country where TB is endemic, a high index of suspicion should be expressed in evaluating breast masses, and TB should be considered in the differential diagnosis.

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