scholarly journals Uterine Artery Embolization as Nonsurgical Treatment of Uterine Myomas

2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
Strinic Tomislav ◽  
Maskovic Josip ◽  
Cambi Sapunar Liana ◽  
Vulic Marko ◽  
Jukic Marko ◽  
...  
Keyword(s):  
Uterine Artery Embolization ◽  
Uterine Artery ◽  
Clinical Symptoms ◽  
Uterine Fibroids ◽  
Normal Activity ◽  
Uneventful Recovery ◽  
Artery Embolization ◽  
Invasive Treatment ◽  
Variable Intensity

The purpose of this study was to evaluate safety, efficacy or complications of uterine artery embolization (UAE). Patients with symptomatic uterine fibroids (n=157) were treated by selective bilateral UAE using 350–500 μm sized polyvinyl alcohol particles. Bilateral UAE was successful in 152 (96.8%) cases. Baseline measures of clinical symptoms and MRI taken before the procedure were compared to those taken 3, 6, and 12 months after embolotherapy. Also, complications and outcomes were analyzed after procedure. All patients had an uneventful recovery and were able to return to normal activity within two weeks of embolization. After the procedure, most patients experienced crampy pelvic pain, of variable intensity, which was well managed with the standard analgesia protocol. Five (3%) of participants had persisting amenorrhea after procedure. None reported any new gynecologic or medical problem during the follow-up period. There were no deaths and no major permanent injuries. Reductions in mean uterine volume were 61% (P<0.01) and in dominant fibroid volume 66% (P≤0.01). The follow-up showed significant improvement of bleeding. In conclusion, uterine artery embolization is a successful, minimal invasive treatment of uterine fibroids that preserves the uterus, had minimal complications, and requires short hospitalization and recovery.

Uterine Artery Embolization is Advanced, Minimally Invasive Treatment for Fibroids with Intervention Procedure: A Case Report

2014 ◽  
Vol 1 (1) ◽  
pp. 47
Author(s):  
Chandrashekhar M. Gattani ◽  
Tejas P. Sadavarte ◽  
Shripad S. Kamble
Keyword(s):  
Minimally Invasive ◽  
Uterine Artery Embolization ◽  
Uterine Artery ◽  
Posterior Wall ◽  
Contrast Study ◽  
Lower Abdomen ◽  
Artery Embolization ◽  
Invasive Treatment ◽  
Intervention Procedure

<p>Uterine Artery Embolization (UAE) has become most effective and minimally invasive alternative treatment over the past many years, especially for women with symptomatic fibroids for whom conservation of uterus is important. Here we are reporting a case of an eighteen year old, unmarried female who presented with pain in lower abdomen and pelvis, menorrhagia and she also noticed gradually increasing lump in pelvis and lower abdomen.</p><p>After clinical examination, patient was referred for radiological investigations, initially ultrasonography was performed which revealed, a large sized posterior wall uterine fibroid measuring approx. 19 x 10 x 18 cm and it was further confirmed on MRI with contrast study. UAE was carried out in order to relieve the symptoms, reduce the size of fibroid and at the same time preserve the uterus. The procedure was uneventful after follow-up for 3 months, there was partial regression in the size of fibroid.</p>

scholarly journals Arterial Embolization in Large Uterine Fibroids : A 4-Year Single Center Experience

2019 ◽  
Vol 7 (10) ◽  
Author(s):  
Volkan Çakır ◽  
Ömür Ballı
Keyword(s):  
Tumor Size ◽  
Uterine Artery Embolization ◽  
Uterine Artery ◽  
Current Knowledge ◽  
Case Reports ◽  
Uterine Fibroids ◽  
Artery Embolization ◽  
Pelvic Mri ◽  
The Impact

Purpose: Current knowledge concerning the use of uterine artery embolization (UAE) in large uterine fibroids is limited with the majority of studies being limited to case reports. The present retrospective study aimed to investigate the impact of UAE on symptoms and tumor size in symptomatic women with at least one large uterine fibroid. Methods: 39 patients undergoing UAE for symptomatic large uterine fibroids (>5cm) were consecutively enrolled in this study. All patients underwent a detailed physical examination and contrast-enhanced pelvic MRI at 3, 6 and 12 months after the procedure. Results: Compared to baseline values (7.8 ± 2.4 cm), the mean diameter of the fibroids significantly reduced at 3rd (5.5 ± 1.7 cm), 6th (4.2 ± 1.3 cm) and 12th (3.1 ± 0.6 cm) months follow-up (p<0.005 for each compared to baseline) implying a 60 % reduction in tumor size at 12 months compared to baseline measurements. At the end of the 12 months follow-up, complete necrosis of the fibroid was achieved in 88%, complete symptom resolution was achieved in 92%, and >50 % reduction in fibroid diameter was acquired in 87 % of the participants. Conclusion: Uterine artery embolization provides 60 % reduction in fibroid volume and a 92 % improvement in fibroid-related symptoms in patients with large fibroids at the end of 12 months follow-up.

Uterine artery embolization: a vascular surgery procedure? One vascular surgery group's experience

Vascular ◽  
2012 ◽  
Vol 20 (5) ◽  
pp. 268-272 ◽  
Author(s):  
Shelby Cooper ◽  
Luis M Oceguera ◽  
Stratton Danes
Keyword(s):  
Vascular Surgery ◽  
Uterine Artery Embolization ◽  
Uterine Artery ◽  
Uterine Fibroids ◽  
Artery Embolization ◽  
Brief Training ◽  
The Mean ◽  
One Year ◽  
Proven Benefit

Uterine artery embolization (UAE) has been performed by interventional radiology since the 1990s for symptomatic uterine fibroids with considerable success. Endovascular-trained vascular surgeons possess the necessary skills to successfully perform this procedure after an adequate but brief training period. Fourteen successful UAE procedures were performed by two vascular surgeons over a one-year period. Indications for the procedures were bleeding (12/14 patients, 86%), pain/bloating/pressure (13/14 patients, 93%) and dyspareunia (2/14 patients, 14%). All patients were initially evaluated by a gynecologist and referred for this procedure. Complications were minor and limited. Clinical follow-up demonstrated near-complete to complete symptom resolution in all but one patient for a 93% short-term success rate. Follow-up ultrasound studies demonstrated a reduction in the uterine fibroid size in all patients three months or more postprocedure. The mean fibroid size reduction was 4.07–3.26 cm (20%), P < 0.005. UAE is a procedure of proven benefit, well-matched to many vascular surgeons’ skills and practice. Up to this point, few vascular surgeons have incorporated this endovascular procedure into their practices. This initial and somewhat limited study demonstrates one vascular surgery group's early success with this procedure.

scholarly journals Comparison of uterine artery embolization and myomectomy: A long-term analysis of 863 patients

2021 ◽  
Vol 5 ◽  
pp. 1
Author(s):  
Jemianne Bautista Jia ◽  
Emilie T. Nguyen ◽  
Anoop Ravilla ◽  
Eric Mastrolonardo ◽  
Jean Min ◽  
...  
Keyword(s):  
Uterine Artery Embolization ◽  
Uterine Artery ◽  
Uterine Fibroids ◽  
Symptomatic Improvement ◽  
Subsequent Pregnancy ◽  
Artery Embolization ◽  
Secondary Intervention ◽  
Significant Difference ◽  
Initial Procedure

Objectives: The objective of this study is to compare the rates of secondary intervention following uterine artery embolization (UAE) versus myomectomy for the treatment of symptomatic uterine fibroids. Material and Methods: This is a multicenter retrospective cohort study. Eight hundred and sixty-three patients are included in this analysis, 451 patients who underwent UAE and 412 patients who underwent myomectomy between January 1, 2008, and December 31, 2012. The UAE group was significantly older than the myomectomy group with a median age of 46 versus 38 (P < 0.0001). Patient data were collected from electronic medical records between the time of their initial procedure and December 31, 2017. The primary endpoint was secondary intervention rate. Secondary endpoints included time to secondary intervention, post-procedural complications, differences in mean hemoglobin levels following the procedures, symptomatic improvement, and subsequent pregnancy outcomes. All statistical analyses were two sided and performed using SAS EG 7.13 (Cary, NC). Results: The median follow-up for the UAE and myomectomy groups was 7 and 7.3 years, respectively. Overall, the rates of secondary intervention were not statistically significant between the UAE and myomectomy groups, 8.9% and 11.2%, respectively (P = 0.26). However, stratified analysis in women aged 30–39 years old demonstrated an increased rate of secondary intervention in the UAE arm with a hazards ratio of 3.76 (P = 0.0099). In patients ≥40 years old, there was no significant difference in secondary intervention rate. Both groups demonstrated a significant increase in mean hemoglobin at 1 year following initial procedure with a mean difference (SD) of 1.8 (2.1) in the UAE group and 1.8 (2.5) in the myomectomy group (P < 0.0001 for both groups). The myomectomy group had a higher rate of post-procedural blood transfusion than the UAE group, 2.9% versus 0.9%, respectively (P = 0.028). Both groups had comparable rates of post-procedural pelvic infection and rehospitalization. Patients with pre-procedural menorrhagia who received UAE reported a higher rate of symptomatic improvement when compared to the myomectomy group, 75.4% versus 49.5% (P < 0.0001). Both groups reported similar rates of improvement in bulk symptoms, 46.1% and 43.2%, respectively (P = 1.0). Conclusion: Overall, UAE and myomectomy have comparable rates of secondary intervention during a median 7-year follow-up period. However, in women between 30 and 39 years of age, UAE resulted in higher rates of secondary intervention. UAE may be more effective in controlling patients’ menorrhagia and has lower rates of post-procedural blood transfusions.

scholarly journals Uterine Artery Embolization (UAE) for Fibroid Treatment – Results of the 7th Radiological Gynecological Expert Meeting

2019 ◽  
Vol 191 (07) ◽  
pp. 630-634 ◽  
Author(s):  
Thomas Kröncke ◽  
Matthias David
Keyword(s):  
Uterine Artery Embolization ◽  
Uterine Artery ◽  
Clinical Success ◽  
Uterine Fibroids ◽  
Artery Embolization ◽  
Published Evidence ◽  
Key Points ◽  
Expert Meeting

Uterine artery embolization (UAE) is a safe and effective organ sparing treatment for fibroid-related symptoms based on a broad range of published evidence including randomized-controlled trials. Indication for treatment by means of UAE are symptomatic uterine fibroids. UAE is an alternative to surgical and medical treatment for uterine fibroids as well treatment by MRgFUS. This consensus paper covers the structural prerequisites, the criteria for technical and clinical success, contraindications, side effects and complications as well as the role of UAE treatment in women wishing to conceive and gives guidance on radiation safety measures and clinical follow-up. Key Points: Citation Format

scholarly journals Uterine Artery Embolization (UAE) for Fibroid Treatment – Results of the 7th Radiological Gynecological Expert Meeting

2019 ◽  
Vol 79 (07) ◽  
pp. 688-692
Author(s):  
Thomas Kröncke ◽  
Matthias David
Keyword(s):  
Uterine Artery Embolization ◽  
Uterine Artery ◽  
Clinical Success ◽  
Uterine Fibroids ◽  
Artery Embolization ◽  
Safety Measures ◽  
Published Evidence ◽  
Expert Meeting

AbstractUterine artery embolization (UAE) is a safe and effective organ sparing treatment for fibroid-related symptoms based on a broad range of published evidence including randomized-controlled trials. Indication for treatment by means of UAE are symptomatic uterine fibroids. UAE is an alternative to surgical and medical treatment for uterine fibroids as well as treatment by MRgFUS. This consensus paper covers the structural prerequisites, the criteria for technical and clinical success, contraindications, side effects and complications as well as the role of UAE treatment in women wishing to conceive and gives guidance on radiation safety measures and clinical follow-up.

scholarly journals Initial experience with HydroPearl microspheres for uterine artery embolization for the treatment of symptomatic uterine fibroids

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Matthew A. Patetta ◽  
Ari J. Isaacson ◽  
Jessica K. Stewart
Keyword(s):  
Uterine Artery Embolization ◽  
Uterine Artery ◽  
Uterine Fibroids ◽  
Invasive Procedure ◽  
Embolic Agent ◽  
Initial Experience ◽  
Success Rates ◽  
Artery Embolization ◽  
Embolic Agents

Abstract Background Uterine Artery Embolization (UAE) is a minimally invasive procedure used to treat symptomatic uterine fibroids. The HydroPearl Microsphere (Terumo Interventional Systems) is an embolic agent approved for UAE and other embolization procedures. The purpose of this article is to describe our initial experience with HydroPearl for UAE in patients with symptomatic uterine fibroids. Twenty-one patients who underwent UAE using HydroPearl Microspheres at a single institution from May 1, 2018 to December 31, 2019 were included in the study. The electronic medical record (EMR) was reviewed for documentation of short- and long-term complications, as well as improvements in menorrhagia and bulk-type symptoms. We also describe unique attributes of the HydroPearl Microsphere that should be considered when utilizing this embolization particle for UAE. Results Of the 21 patients, 18 had a 3-month or later post-procedure follow-up documented in the EMR and were included in the analysis. The average time between the UAE procedure and the most recent clinical note was 145 days. Sixteen patients reported symptoms of menorrhagia and 13 reported bulk symptoms prior to the UAE procedure. On follow-up, 13/16 patients (81%) and 12/13 patients (92%) experienced improvement in menorrhagia and bulk symptoms, respectively. The only recorded complication was amenorrhea in 4 patients (22%) who had an average age of 51 years. Conclusions Several characteristics of HydroPearl Microsphere may prove helpful when considering these embolic particles for use in UAE. Our initial experience with this embolic agent suggest that the reatment response for menorrhagia and bulk symptoms are largely similar to success rates reported in the literature for other embolic agents. Larger studies are needed to evaluate the safety and efficacy of this embolic particle for this indication.

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