scholarly journals Randomized Split-Mouth Study on Postoperative Effects of Palmitoylethanolamide for Impacted Lower Third Molar Surgery

ISRN Surgery ◽  
2011 ◽  
Vol 2011 ◽  
pp. 1-6 ◽  
Author(s):  
Christian Bacci ◽  
Giulia Cassetta ◽  
Bruno Emanuele ◽  
Mario Berengo
Keyword(s):  
Postoperative Pain ◽  
Repeated Measures ◽  
Third Molar ◽  
Third Molar Surgery ◽  
Third Molar Extraction ◽  
Drug Tolerability ◽  
Repeated Measures Analysis ◽  
Surgical Extraction ◽  
Over Time ◽  
Molar Extraction

The aim of this study was to assess the efficacy of Normast 300 mg in reducing swelling and pain after the surgical extraction of impacted lower third molars. Materials and Methods. A randomized, split-mouth, single-blind study was conducted on 30 patients between 18 and 30 years of age requiring lower third molar extraction. Patients underwent bilateral extractions in a randomized sequence, one extraction being performed under Normast treatment. The Normast treatment involved 2 tablets a day for 15 days. The parameters assessed at each procedure were trismus, swelling, pain, NSAID consumption, postoperative complications, drug tolerability, and safety. The results obtained were processed using repeated measures analysis of variance. Results. Perceived postoperative pain was reportedly significantly milder on Normast treatment than control. The trend of the means differed over time (P<.0001) and between the two extraction groups (P<.0221). On the other hand, for edema and trismus, the trend differed over time for both groups but did not differ between the two groups. Discussion. Our analyses indicate that patients experienced significantly less postoperative pain when they were treated with Normast. Conclusions. Administering Normast improves the postoperative course—in terms of pain—after lower third molar extraction.

Oral pregabalin for postoperative pain relief after third molar extraction: a randomized controlled clinical trial

2015 ◽  
Vol 20 (7) ◽  
pp. 1819-1826 ◽  
Author(s):  
Maria Victoria Olmedo-Gaya ◽  
Francisco J. Manzano-Moreno ◽  
Rafael Galvez-Mateos ◽  
Maria Paloma González-Rodriguez ◽  
Cristina Talero-Sevilla ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Postoperative Pain ◽  
Pain Relief ◽  
Third Molar ◽  
Postoperative Pain Relief ◽  
Controlled Clinical Trial ◽  
Randomized Controlled Clinical Trial ◽  
Randomized Controlled ◽  
Third Molar Extraction ◽  
Molar Extraction

scholarly journals Piezo-surgery technique and intramuscular dexamethasone injection to reduce postoperative pain after impacted mandibular third molar surgery: a randomized clinical trial

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Wissam Nehme ◽  
Youssef Fares ◽  
Linda Abou-Abbas
Keyword(s):  
Clinical Trial ◽  
Postoperative Pain ◽  
Third Molar ◽  
Mouth Opening ◽  
Mean Difference ◽  
Third Molar Surgery ◽  
Third Molars ◽  
Dexamethasone Group ◽  
Mandibular Third Molar ◽  
Surgical Extraction

Abstract Background Surgical extraction of the impacted mandibular third molar is commonly associated with postoperative pain, swelling, and trismus. Usually, rotatory instruments like burs have been used for osteotomy, while Piezosurgery is an innovative technique introduced to overcome the weaknesses related to the conventional technique. In addition, Dexamethasone administration before the extraction of impacted third molars is an efficient way to reduce postoperative pain due to robust anti-inflammatory activity. The purpose of the study is to evaluate the effect of piezo-surgery and dexamethasone injection on postoperative sequelae after the surgical extraction of impacted mandibular third molars, and ultimately to compare their effect on reducing postoperative pain. Methods A randomized controlled clinical trial was conducted with a sample of 80 patients. Participants were divided into four groups: Group 1 (Conventional rotatory), Group 2 (Conventional rotatory with 8 mg dose of dexamethasone 30 min before surgery), Group 3 (Piezo-surgery), and Group 4 (Piezo-surgery with 8 mg dose of dexamethasone 30 min before surgery). The outcome variables were surgical working time calculated in minutes, maximal mouth opening measured in millimeters using Vernier Caliper at baseline and day 3 and postoperative pain assessed using a Visual Analog Scale (VAS) on days 1, 3, and 7. Results The surgical working time was longer in piezo-surgery groups compared with the conventional rotatory instruments groups (15.82 ± 3.47 vs 23.33 ± 2.54; p value < 0.0001). The lowest reduction in mouth opening between baseline and 3rd-day post-op was found in the Piezo-surgery with Dexamethasone group (mean difference = 5.0, SD = 3.9, p value < 0.0001) followed by the Piezosurgery without Dexamethasone group (mean difference = 5.8, SD = 4.5, p value < 0.0001) and the highest average was reported by the Conventional rotatory without Dexamethasone (mean difference = 9.7, SD = 4.5, p value < 0.0001. In the four groups, the mean pain score was highest on the 1st day and gradually decreased over the following days. Comparison of the 1st and 3rd postoperative pain between groups revealed a lowest mean pain score in the Piezo-surgery with Dexamethasone group, followed by Conventional rotatory with Dexamethasone group and a highest mean score in the Conventional rotatory without Dexamethasone group (p value < 0.0001). Conclusion The association of Piezosurgery osteotomy and Dexamethasone intramuscular injection could be an effective combination to reduce postoperative pain and trismus after impacted third molar surgery. Trial registration: NCT04889781 (https://clinicaltrials.gov/), Date of Registration: 17/05/2021 (retrospectively registered), https://clinicaltrials.gov/ct2/show/NCT04889781?term=NCT04889781&draw=2&rank=1

scholarly journals Third Molar Extraction: Irrigation and Cooling with Water or Sterile Physiological Solution: A Double-Blind Randomized Study

2021 ◽  
Vol 9 (4) ◽  
pp. 40
Author(s):  
Luca Sbricoli ◽  
Alessia Cerrato ◽  
Anna Chiara Frigo ◽  
Gastone Zanette ◽  
Christian Bacci
Keyword(s):  
Postoperative Pain ◽  
Randomized Study ◽  
Third Molar ◽  
Physiological Solution ◽  
Wilcoxon Test ◽  
University Hospital ◽  
Double Blind ◽  
Third Molar Extraction ◽  
Surgical Field ◽  
Molar Extraction

Background: The present study aimed to ascertain whether any significant reduction in patients’ postoperative pain and inflammation could be achieved by using sterile physiological solution instead of normal water to irrigate the surgical field and cool the dental bur during third molar extractions. Methods: The study concerned 22 patients (11 females and 11 males) in good general health, who were referred to the Dental Clinic at Padova University hospital for lower third molar extractions. They were randomly assigned to two groups. Only the fluid used to irrigate the surgical field and cool the dental bur differed between the two study groups, being sterile physiological solution for group A, and mains water for group B. Postoperative pain, swelling, trismus and inflammation with high sensitivity CRP where measured and statistically evaluated. The numerosity of our sample was calculated on the grounds of an endpoint based on data in the literature. Results: Eighteen patients needed bilateral extractions, and 4 required only one extraction, so a total of 40 third molars were extracted. A sterile physiological solution was used to irrigate the surgical field in 20 extractions, while water was used in the other 20 cases. Data analysis with Wilcoxon test show no differences between the two groups (p < 0.05). Conclusions: no differences between groups for any of the parameters considered, after third molar extraction procedures undertaken using either sterile physiological solution or water for irrigation and cooling purposes.

scholarly journals Evaluation of efficacy of submucosal tramadol after mandibular third molar surgery: a prospective pilot study

2019 ◽  
Vol 7 (11) ◽  
pp. 4320
Author(s):  
Karan V. Panchal ◽  
Navin S. Shah ◽  
Pratik Agrawal ◽  
Parshwa N. Shah
Keyword(s):  
Pilot Study ◽  
Maxillofacial Surgery ◽  
Third Molar ◽  
Mouth Opening ◽  
Analgesic Efficacy ◽  
Third Molar Surgery ◽  
Oral And Maxillofacial Surgery ◽  
Third Molar Extraction ◽  
Mandibular Third Molar ◽  
Surgical Extraction

Background: Surgical extraction of mandibular third molar is one of the most commonly performed procedure in oral and maxillofacial surgery. Its removal causes swelling, trismus, and moderate to severe pain which can be treated with various NSAID’s drugs, which have numerous side effects and gastric disturbances. In order to bypass such disturbances, Tramadol may be considered as an alternative for such patients. The aim of the study was to evaluate analgesic efficacy of submucosal tramadol and its implication over swelling and mouth opening after mandibular third molar surgery.Methods: This is a prospective study where in after post-surgical extraction of mandibular third molar, efficacy of submucosal injection of tramadol is evaluated in terms of pain and its implication over swelling and mouth opening.Results: The present study suggested there was statistically significant VAS score for pain after submucosally injecting tramadol post-surgical extraction of mandibular third molar in the following visits- 4hourly, 8hourly and 24hourly. In respect to swelling, statistically significant values was noted during 24hr and 72 h our post extraction. Also in case of mouth opening, statistically significant values were found 24 hourly.Conclusions: The present pilot study concluded that submucosal tramadol post mandibular third molar extraction has been effective in reducing pain, limiting post-extraction swelling and less impacting mouth opening by inducing less complications thereby bypassing gastric disturbances.

scholarly journals Comparison of oral versus sublingual piroxicam during postoperative pain management after lower third molar extraction

2011 ◽  
Vol 40 (3) ◽  
pp. 292-297 ◽  
Author(s):  
P.A.K. Trindade ◽  
F.P.M. Giglio ◽  
B.L. Colombini-Ishikiriama ◽  
A.M. Calvo ◽  
K.C.S. Modena ◽  
...  
Keyword(s):  
Pain Management ◽  
Postoperative Pain ◽  
Third Molar ◽  
Postoperative Pain Management ◽  
Third Molar Extraction ◽  
Molar Extraction

scholarly journals Comparison of Propofol-Remifentanil Versus Propofol-Ketamine Deep Sedation for Third Molar Surgery

2012 ◽  
Vol 59 (3) ◽  
pp. 107-117 ◽  
Author(s):  
Kyle J. Kramer ◽  
Steven Ganzberg ◽  
Simon Prior ◽  
Robert G. Rashid
Keyword(s):  
Deep Sedation ◽  
Third Molar ◽  
Controlled Study ◽  
Third Molar Surgery ◽  
Control Group ◽  
Oral Surgical Procedures ◽  
Third Molar Extraction ◽  
Surgical Extraction ◽  
Recovery Times ◽  
Double Blinded

This study aimed to compare continuous intravenous infusion combinations of propofol-remifentanil and propofol-ketamine for deep sedation for surgical extraction of all 4 third molars. In a prospective, randomized, double-blinded controlled study, participants received 1 of 2 sedative combinations for deep sedation for the surgery. Both groups initially received midazolam 0.03 mg/kg for baseline sedation. The control group then received a combination of propofol-remifentanil in a ratio of 10 mg propofol to 5 μg of remifentanil per milliliter, and the experimental group received a combination of propofol-ketamine in a ratio of 10 mg of propofol to 2.5 mg of ketamine per milliliter; both were given at an initial propofol infusion rate of 100 μg/kg/min. Each group received an induction loading bolus of 500 μg/kg of the assigned propofol combination along with the appropriate continuous infusion combination . Measured outcomes included emergence and recovery times, various sedation parameters, hemodynamic and respiratory stability, patient and surgeon satisfaction, postoperative course, and associated drug costs. Thirty-seven participants were enrolled in the study. Both groups demonstrated similar sedation parameters and hemodynamic and respiratory stability; however, the ketamine group had prolonged emergence (13.6 ± 6.6 versus 7.1 ± 3.7 minutes, P = .0009) and recovery (42.9 ± 18.7 versus 24.7 ± 7.6 minutes, P = .0004) times. The prolonged recovery profile of continuously infused propofol-ketamine may limit its effectiveness as an alternative to propofol-remifentanil for deep sedation for third molar extraction and perhaps other short oral surgical procedures, especially in the ambulatory dental setting.

Nyer Zet-Ractor – Innovative Multifunctional Concept of Retraction

2019 ◽  
Author(s):  
Nyer Firdose
Keyword(s):  
Third Molar ◽  
Third Molar Surgery ◽  
Third Molar Extraction ◽  
Post Operative Pain ◽  
Mandibular Third Molar ◽  
The Common ◽  
Mandibular Third Molar Surgery ◽  
The Impact ◽  
Molar Extraction

Post-operative pain and swelling is one of the common complications following mandibular third molar surgery leading to very disturbing days immediately following third molar extraction. On considering the impact of such post-operative sequelae on the patient’s quality of life, it is necessary to exercise preventive measures to minimize the occurrence of such complications / untoward events. Although many retractors are already in application for retraction of tissues during the third molar extraction, this manuscript describes an innovative multifunctional concept “Nyer Zet-ractor” designed for retraction and isolation without limiting the accessibility to the surgical area in mandibular third molar surgery. The “Nyer Zet-ractor” described in this manuscript is an innovative device which provides the advantages like clear access, continuous visibility and excellent isolation of the surgical site unlike conventional retractors with minimal retractive forces thereby reducing post-operative pain and swelling. Nyer Zet-ractor implements a multifunctional concept of retraction making it an efficient, easy to use, and exerts a known and finite amount of force, thereby avoiding tissue damage.

Sign in / Sign up

Export Citation Format

Share Document