scholarly journals Necrotizing Enterocolitis in Very Low Birth Weight Infants: A Systemic Review

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Bhoomika K. Patel ◽  
Jigna S. Shah

Necrotizing enterocolitis (NEC) is the most common serious gastrointestinal disorder affecting very preterm or very low birth weight infants. The risk is inversely proportional to gestational age and weight at birth. Fetal growth restriction and compromise may be additional specific risk factors. Despite extensive research and animal studies etiopathogenesis, preventive strategies and management options remain controversial. The present paper reviews the literature for recent advances and newer insights for changing epidemiological trends, pathogenesis, role of inflammatory cytokines, and various preventive and management strategies.

PEDIATRICS ◽  
1977 ◽  
Vol 60 (4) ◽  
pp. 535-538
Author(s):  
DIANA M. WILLIS ◽  
JOANN CHABOT ◽  
INGEBORG C. RADDE ◽  
GRAHAM W. CHANCE

In recent years necrotizing enterocolitis (NEC) has become a major problem in neonatal intensive care units. Recent incidences as high as 8% in all infants with a birth weight less than 2.5 kg and 14% in those with a birth weight less than 1.5 kg have been reported from one center.1Despite intensive searches for possible causative factors, no definite entity has been identified, but asphyxia,2 circulatory changes associated with exchange transfusion,3 umbilical vessel catheterization,4 immature immune status,5infection,6-8 and hypertonic feedings9 have all been implicated. In the course of a series of nutritional studies involving thriving very-low-birth-weight infants we


2020 ◽  
Vol 40 (11) ◽  
pp. 1652-1661
Author(s):  
Atoosa F. Craighead ◽  
Aaron B. Caughey ◽  
Anoshua Chaudhuri ◽  
Leah Yieh ◽  
Alyssa R. Hersh ◽  
...  

2013 ◽  
Vol 48 (3) ◽  
pp. 562-567 ◽  
Author(s):  
Nehama Linder ◽  
Naama Hammel ◽  
Adriana Hernandez ◽  
Elena Fridman ◽  
Elena Dlugy ◽  
...  

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