A study of adverse drug reactions to radio contrast media in a tertiary care teaching rural hospital

2014 ◽  
Vol 3 (2) ◽  
pp. 133 ◽  
Author(s):  
Nilay Modi ◽  
Kesha Vaidya ◽  
Sneh Dudhia ◽  
Rima Shah ◽  
Sanjay Date
Keyword(s):  
Contrast Media ◽  
Adverse Drug Reactions ◽  
Tertiary Care ◽  
Rural Hospital ◽  
Drug Reactions ◽  
Care Teaching

scholarly journals PATTERN OF ADVERSE DRUG REACTIONS IN A TERTIARY CARE TEACHING HOSPITAL: A CROSS-SECTIONAL STUDY

2017 ◽  
Vol 10 (3) ◽  
pp. 170 ◽  
Author(s):  
Sangeetha Raja ◽  
Jamuna Rani R ◽  
Kala P
Keyword(s):  
Adverse Drug Reactions ◽  
Teaching Hospital ◽  
Antimicrobial Agents ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Drug Reactions ◽  
Cross Sectional ◽  
Tertiary Care Teaching Hospital ◽  
Care Teaching

ABSTRACTObjective: The aim of this study was to carry out adverse drug reactions (ADRs) monitoring in various departments of a tertiary care teaching hospital.Methods: A cross-sectional study was conducted on ADRs reported in the hospital from December 2012 to May 2013 after obtaining InstitutionalEthics Committee approval.Results: A total of 40 ADRs were reported, 47.50% were males and 52.50% were females. The female adult population was 45%. The majority of ADRswere due to antimicrobial agents especially beta-lactam antibiotics (42.5%) followed by NSAIDs (7.50%). A maximum number of patients (75%)were reported with dermatological manifestations. The department of medicine reported the highest number of ADRs (37.5%). As per Naranjo’sprobability scale, 62.5% reports were assessed as probable. 62.5% reports were documented as mild according to Modified Hartwig’s criteria forseverity assessment.Conclusion: This study was done to sensitize the practicing physicians on the importance of adverse drug monitoring and reporting.Keywords: Pharmacovigilance, Adverse drug reactions, Tertiary care teaching hospital, Antimicrobial agents.

scholarly journals PHARMACOVIGILANCE OF RADIOGRAPHIC CONTRAST-INDUCED ADVERSE DRUG REACTIONS IN A TERTIARY CARE HOSPITAL OF SOUTH INDIA

2017 ◽  
Vol 10 (7) ◽  
pp. 364
Author(s):  
Inbaraj Sd ◽  
Sidhu Ganesh R ◽  
Muthiah Ns
Keyword(s):  
Contrast Media ◽  
Adverse Drug Reactions ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Drug Reactions ◽  
Contrast Administration ◽  
Intravenous Contrast ◽  
Radiographic Contrast ◽  
Radiographic Contrast Media

Objective: The aim of this study was to analyze the nature and incidence of adverse drug reactions (ADRs) to radiographic contrast media (oral and intravenous) reported during a 1½ years’ period in a tertiary care hospital in South India.Methods: The study was an observational prospective study of ADRs to radiographic contrast media (oral and intravenous) observed during a period of 1½ years from July 2014 to October 2015 in Department of Radio Diagnosis at Sree Balaji Medical College and Hospital, Chromepet. The observations were analyzed for demographic profile, frequency, severity, causality, and temporal relationship of contrast administration to the occurrence of ADRs.Results: A total of 33 ADRs were observed for oral and intravenous radiographic contrast media administered for radiographic study for the above-mentioned period. It included 17 (51.5%) males and 16 (48.5%) females. Among the 33 ADRs, 19 (57%) were for oral and intravenous radiographic contrast and 14 (42%) for intravenous radiographic contrast alone. The most frequent ADRs were vomiting and nausea 16 (48%), skin rashes 9 (27%), and thrombophlebitis 9 (27%). As per Naranjo’s algorithm and WHO causality assessment, all reactions are probable except in one patient who received intravenous contrast administration was possible. According to the Hartwig severity scale, 23 (69%) reactions were mild, 7 (21%) reactions were moderate, and 3 (9%) reactions were severe. There was no fatality observed. Adverse events required immediate treatment in 22 (66%). Most of the reactions, i.e., 21 (63%) appeared immediately after contrast administration. 12 (36%) reactions appeared within next 30 minutes after contrast administration.Conclusion: The common adverse reactions to radiographic contrast were mild in severity such as nausea, vomiting, skin rashes, and giddiness. Most of the reactions occur immediately after administration of contrast. The causality of majority of the ADRs is probable. Pharmacovigilance is an important tool in detection, reporting and thereby preventing ADRs due to radiographic contrast media.

scholarly journals STUDY TO EVALUATE SEVERE ADRS IN A TERTIARY CARE TEACHING HOSPITAL

2017 ◽  
pp. 55-58
Author(s):  
A. R. Malahat ◽  
C. Deepa Latha ◽  
Sudhakar K. ◽  
Deepika Baloju ◽  
G. Vijayalakshmi
Keyword(s):  
Adverse Drug Reactions ◽  
Teaching Hospital ◽  
Prospective Observational Study ◽  
Healthcare Professionals ◽  
Tertiary Care ◽  
Care Centre ◽  
Drug Reactions ◽  
Tertiary Care Centre ◽  
Tertiary Care Teaching Hospital ◽  
Care Teaching

Objective: This study attempts to analyze the severe ADRs in a tertiary care centre and assess their seriousness, outcome, causality and severity. We emphasize on the need for reporting of ADRs by all healthcare professionals as it will reduce the burden of morbidity due to drugs and ensure better and more efficient healthcare. To analyse and evaluate the severe ADVERSE DRUG REACTIONs reported from various departments in a Tertiary care Teaching hospital.Methods: It is a prospective observational study that was carried out over a period of 6 mo (from July 2016 to December 2016) to assess the percentage of severe adverse drug reactions reported to the Pharmacovigilance cell of a tertiary care teaching hospital. The data collected included patient’s demographic details, presenting complaints, clinical diagnosis and details of the drug(s) prescribed. The data was analysed for causality (as per the WHO-UMC scale) and severity (as per Hartwig and Siegel scale).Results: Out of 64 ADRs reported, 17 were serious. The majority of serious ADRs were categorized as probable (82.35%), whilst 1(5.8%) was categorized as possible and 2(11.76%) as certain in nature. The criteria for the majority of serious ADRs were hospitalization (%) followed by intervention to prevent permanent impairment or damage (%).Conclusion: The highest percentage of severe cases was reported with Antitubercular therapy (23.5%) followed by analgesics (23%) and anti epileptic agents (17.6%).

Cost of Adverse Drug Reactions in a South Indian Tertiary Care Teaching Hospital

2012 ◽  
Vol 52 (4) ◽  
pp. 559-565 ◽  
Author(s):  
Thiyagu Rajakannan ◽  
Surulivelrajan Mallayasamy ◽  
Vasudeva Guddattu ◽  
Asha Kamath ◽  
Rajesh Vilakkthala ◽  
...  
Keyword(s):  
Adverse Drug Reactions ◽  
Teaching Hospital ◽  
Tertiary Care ◽  
Drug Reactions ◽  
Tertiary Care Teaching Hospital ◽  
Care Teaching ◽  
South Indian
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