scholarly journals The comparison of complete blood count parameters between acute and chronic peripheral arterial disease

2022 ◽  
Vol 11 (1) ◽  
pp. 111
Author(s):  
Mehmet Cosgun ◽  
Yilmaz Gunes ◽  
Asli Mansiroglu ◽  
Isa Sincer ◽  
Gulali Aktas ◽  
...  
Keyword(s):  
Peripheral Arterial Disease ◽  
Blood Count ◽  
Complete Blood Count ◽  
Arterial Disease ◽  
Peripheral Arterial

Complete blood count parameters in peripheral arterial disease

2019 ◽  
Vol 22 (3) ◽  
pp. 187-191 ◽  
Author(s):  
Yusuf Velioglu ◽  
Ahmet Yuksel
Keyword(s):  
Peripheral Arterial Disease ◽  
Blood Count ◽  
Complete Blood Count ◽  
Arterial Disease ◽  
Peripheral Arterial

Editorial : Full Blood Count and Peripheral Arterial Disease Severity and Prognosis

2017 ◽  
Vol 15 (2) ◽  
pp. 94-95
Author(s):  
Konstantinos Spanos ◽  
Miltiadis Matsagkas ◽  
Athanasios Giannoukas
Keyword(s):  
Peripheral Arterial Disease ◽  
Disease Severity ◽  
Blood Count ◽  
Arterial Disease ◽  
Full Blood Count ◽  
Peripheral Arterial

scholarly journals Clopidogrel Induced Haematological Dyscrasia: A Case Report

1970 ◽  
Vol 5 (2) ◽  
pp. 89-90
Author(s):  
Abdul Wadud Chowdhury ◽  
Amanullah Bin Siddiq ◽  
AEM Masharul Islam ◽  
Amitav Saha
Keyword(s):  
Percutaneous Coronary Intervention ◽  
Acute Coronary Syndrome ◽  
Blood Count ◽  
Complete Blood Count ◽  
Coronary Intervention ◽  
Arterial Disease ◽  
Coronary Syndrome ◽  
Elective Percutaneous Coronary Intervention ◽  
Percutaneous Coronary ◽  
Peripheral Arterial

Clopidogrel is an analogue of ticlopidine, used for reduction of atherosclerotic events in patients with acute coronary syndrome (ACS), stroke, peripheral arterial disease and for elective percutaneous coronary intervention (PCI). It selectively and irreversibly blocks ADP binding to platelets. Its primary side effect is bleeding. However potentially fatal types of haematological dyscrasia such as aplastic anaemia, neutropenia, thrombocytopenia, pancytopenia may be associated with clopidogrel therapy. A 50 years old diabetic, hypertensive lady with angina was started to treat with clopidogrel along with other anti-ischaemic and anti-hypertensive drugs. Subsequently the patient developed leucopenia and thrombocytopenia after starting of clopidogrel. Five days later her complete blood count returned to normal after withdrawal of both anti platelets. Aspirin was re-introduced with great precaution. Later repeat leucocyte and platelet count were found to be normal. At follow- up 1 month after discharge patient found asymptomatic with normal blood count. To the best of our knowledge, clopidogrel induced haematological dyscrasia was not reported earlier in our country. Key words: Acute coronary syndrome; percutaneous coronary intervention. DOI: 10.3329/uhj.v5i2.4563 University Heart Journal Vol.5(2) July 2009 pp.89-90

Abstract 13909: A Novel Photon-powered Biologic Gel for Enhanced Wound Healing in a Peripheral Arterial Disease Model

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Yuanjia Zhu ◽  
Jinsuh Jung ◽  
Shreya Anilkumar ◽  
Akshara D Thakore ◽  
Justin M Farry ◽  
...  
Keyword(s):  
Wound Healing ◽  
Peripheral Arterial Disease ◽  
Complete Blood Count ◽  
Disease Model ◽  
Sodium Hyaluronate ◽  
Arterial Disease ◽  
Wound Dressings ◽  
Growth Media ◽  
Artery Ligation ◽  
Peripheral Arterial

Introduction: Synechococcus elongatus is a cyanobacterium that grows photoautotrophically. We hypothesized that a biologic gel containing S. elongatus could provide O 2 via photosynthesis to ischemic tissue due to peripheral arterial disease to accelerate wound healing. Methods: Sodium hyaluronate powder was mixed with cyanobacterial growth media BG11 at 2wt% to create the gel. S. elongatus was added at 100 million cells/mL to create the biologic gel. Wistar rats (control, n=12; gel, n=10; biologic gel in light, n=13; biologic gel in dark, n=10), after femoral artery ligation, received an ipsilateral wound of 1cm in diameter on the tarsal surface using electrocautery. Wound dressings were changed daily. Lesions were harvested on day 7 for histology evaluation, and blood samples were collected. Results: Rat tarsal tissue O 2 level had the largest fold change after applying biologic gel in light (7.0±1.5) compared to the control (1.7±0.3, p =.004), gel (2.6±0.4, p =.0007), and biologic gel in dark groups (1.8±0.3, p <.0001). Tarsal lesions after 7 days of treatment are shown in Fig.1A . Compared to controls, average wound areas were the smallest in rats receiving biologic gel in light on days 3, 5, and 7 ( Fig.1B ). Rats that received biologic gel in light took 12±1.1 days to heal, faster than the control, gel, and biologic gel in dark groups ( Fig.1C ). C-reactive protein level was zero for all rats, and none had positive blood culture. There was no difference in complete blood count on day 7 among the groups. Rats that received biologic gel in light compared to other groups demonstrated less tissue destruction and enhanced remodeling on day 7 ( Fig.1D-K ). Conclusions: The sodium hyaluronate- S. elongatus biologic gel was effective in accelerating wound healing in a peripheral arterial disease model by delivering oxygen to ischemic tissues. This photon-powered biologic gel shows potential for application as a novel wound dressing capable of promoting tissue formation and remodeling.

P5337Neutrophil-lymphocyte ratio and peripheral arterial disease in HIV infection

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
N Y Ortega-Zaragoza ◽  
J C Bollo-Pazos ◽  
J P Alvarez-Mendoza ◽  
J Mondaca-Figueroa ◽  
M Molina-Alvarado ◽  
...  
Keyword(s):  
Peripheral Arterial Disease ◽  
Hiv Infection ◽  
Complete Blood Count ◽  
Ankle Brachial Index ◽  
Hdl Cholesterol ◽  
Arterial Disease ◽  
Neutrophil Lymphocyte Ratio ◽  
Lymphocyte Ratio ◽  
Increased Risk ◽  
Peripheral Arterial

Abstract Background/Introduction While antiretroviral therapy has increased survival in HIV-infected patients, cardiovascular mortality is now their leading cause of death. Together with a high prevalence of traditional cardiovascular risk factors in HIV infection, chronic inflammation may be also responsible of an increased risk of cardiovascular diseases. Purpose To determine the association between a systemic inflammation-based biomarker, the neutrophil-lymphocyte ratio, and the occurrence of peripheral arterial disease in HIV infected patients. Methods In a case-control design, 41 patients with peripheral arterial disease and HIV infection were compared to 119 patients with HIV infection but no peripheral arterial disease. All patients were recruited at a Regional Hospital. The ankle-brachial index was measured in all subjects and peripheral arterial disease was defined as an ankle-brachial index >0.9. The neutrophil-lymphocyte ratio was assessed using neutrophil and lymphocyte levels in the complete blood count measurement, from routine hemograms performed six to twelve months before measurement of the ankle-brachial index. The cut-off of neutrophil-lymphocyte ratio >2 was used to categorize patients into low- and high- neutrophil-lymphocyte ratio groups. Odds ratios (OR) with 95% confidence intervals were used to estimate the strength of association. In order to control for potential confounders, a multiple logistic regression model was used. Results There was a significant association between elevated neutrophil-lymphocyte ratio and the presence of peripheral arterial disease (OR 7.25 [3.32–15.85], after adjustment for age (OR 1.07 [1.04–1.11]), smoking index (OR 1.12 [1.02–1.24]. Other considered variables did not contribute to the model (HDL-cholesterol, LDL-cholesterol, triglycerides, sex, diabetes, obesity and treatment). Conclusions The ankle-brachial index is a simple, cost-effective and validated method to assess peripheral arterial disease, which its presence increases the risk of cardiovascular disease morbidity and mortality. The neutrophil-lymphocyte ratio is a simple, rapid and novel inflammation parameter, that may help to identify HIV-infected patients with a higher risk of peripheral arterial disease.

Management of Peripheral Arterial Disease

2006 ◽  
Vol 39 (3) ◽  
pp. 44
Author(s):  
WILLIAM E. GOLDEN ◽  
ROBERT H. HOPKINS
Keyword(s):  
Peripheral Arterial Disease ◽  
Arterial Disease ◽  
Peripheral Arterial

Surgical and endovascular hybrid approach in peripheral arterial disease of the lower limbs

VASA ◽  
2016 ◽  
Vol 45 (5) ◽  
pp. 417-422 ◽  
Author(s):  
Anouk Grandjean ◽  
Katia Iglesias ◽  
Céline Dubuis ◽  
Sébastien Déglise ◽  
Jean-Marc Corpataux ◽  
...  
Keyword(s):  
Mortality Rate ◽  
Peripheral Arterial Disease ◽  
Limb Salvage ◽  
Hybrid Approach ◽  
Arterial Disease ◽  
Early Mortality ◽  
Secondary Patency ◽  
Limb Salvage Rate ◽  
Peripheral Arterial ◽  
Salvage Rate

Abstract. Background: Multilevel peripheral arterial disease is frequently observed in patients with intermittent claudication or critical limb ischemia. This report evaluates the efficacy of one-stage hybrid revascularization in patients with multilevel arterial peripheral disease. Patients and methods: A retrospective analysis of a prospective database included all consecutive patients treated by a hybrid approach for a multilevel arterial peripheral disease. The primary outcome was the patency rate at 6 months and 1 year. Secondary outcomes were early and midterm complication rate, limb salvage and mortality rate. Statistical analysis, including a Kaplan-Meier estimate and univariate and multivariate Cox regression analyses were carried out with the primary, primary assisted and secondary patency, comparing the impact of various risk factors in pre- and post-operative treatments. Results: 64 patients were included in the study, with a mean follow-up time of 428 days (range: 4 − 1140). The technical success rate was 100 %. The primary, primary assisted and secondary patency rates at 1 year were 39 %, 66 % and 81 %, respectively. The limb-salvage rate was 94 %. The early mortality rate was 3.1 %. Early and midterm complication rates were 15.4 % and 6.4 %, respectively. The early mortality rate was 3.1 %. Conclusions: The hybrid approach is a major alternative in the treatment of peripheral arterial disease in multilevel disease and comorbid patients, with low complication and mortality rates and a high limb-salvage rate.

Sign in / Sign up

Export Citation Format

Share Document