The Role Of Inflammatory Cytokines In Traumatic Head Injury

Background: Research has provided evidence that malnutrition screening tool (NUTRIC) score has a relation with interleukin-6 but not with other cytokines. In addition, the relation between malnutrition screening tool (NUTRIC) score and some nutritional parameters has not yet been studied in traumatic head injured patients. Therefore, the aim of the current study is examining the relation between malnutrition screening tool (NUTRIC) score and serum pro- and anti-inflammatory cytokines levels and some nutritional parameters in patients with traumatic head injury in the intensive care unit (ICU) of General Teaching Hospital in Sulaimani, the Kurdistan Region of Iraq in 2016-17. Methods: Using appropriate methods and tools, the patients’ (NUTRIC) score, mid-upper arm circumference (MUAC), disease severity and organ dysfunction, concentration level of serum cytokines (IL-6) were assessed within 24 hours after admission. All of the mentioned measurements except the serum interleukin were also assessed on days 6 and 13 of staying in ICU. Afterwards, in order to examine the relationship between the study’s variables, the collected data were analyzed using Mann-Whitney U test through SPSS 22.0. Results: The results of data analysis using Mann-Whitney U and independent samples T-tests revealed that there was a significant relation between malnutrition screening tool (NUTRIC) score and the studied interleukin (IL-6) within 24 hours after ICU admission. Other studied variables that had a significant association with the patients’ (NUTRIC) score within 24 hours after ICU admission were APACHE II score, SOFA score, and MUAC, this significant association has been seen on days 6 and 13 after ICU admission between malnutrition screening tool (NUTRIC) score and serum cytokines (IL-6) APACHE II, and SOFA scores. Conclusion: The results of the present study revealed that pro-inflammatory cytokines (IL-6) along with other factors such as APACHE II and SOFA had significantly higher among patients with risk of malnutrition. Keywords: pro-inflammatory cytokines, traumatic head injury (THI), nutritional score

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Role of a dentist in comprehensive management of a comatose patient with post traumatic head injury and neuropathological chewing

Indian Journal of Palliative Care ◽

10.4103/0973-1075.132639 ◽

2014 ◽

Vol 20 (2) ◽

pp. 146 ◽

Cited By ~ 1

Author(s):

Aditi Nanda ◽

Dheeraj Koli ◽

Sapna Daksh ◽

Mahesh Verma ◽

Sunanda Sharma

Keyword(s):

Head Injury ◽

Comatose Patient ◽

Traumatic Head Injury ◽

Comprehensive Management ◽

Traumatic Head ◽

Post Traumatic

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Intentional Head Injury: Survivor Victim's Profile, Gender Differences and Role of Alcohol Use at Manipal Teaching Hospital, Pokhara, Nepal

Birat Journal of Health Sciences ◽

10.3126/bjhs.v2i1.17284 ◽

2017 ◽

Vol 2 (1) ◽

pp. 102-105

Author(s):

Alok Atreya ◽

T Kanchan ◽

BG Karmacharya

Keyword(s):

Head Injury ◽

Alcohol Use ◽

Teaching Hospital ◽

Head Injuries ◽

Radiological Finding ◽

Physical Assault ◽

Traumatic Head Injury ◽

Minimum Age ◽

Traumatic Head

IntroductionHead is a vulnerable area in human body and also a favorable site for assaults which is easily accessible by assailant's raised arms. ObjectiveThe objective of this study was to evaluate the socio demographic spectrum, severity, radiological findings and outcome of victims assaulted to the head. Furthermore, the study aims to correlate such findings to the role of alcohol use in Nepalese context. MethodologyThis longitudinal prospective study includes victims of traumatic head injury as a result of physical assault who were admitted in the Neurosurgery Unit of Manipal Teaching Hospital Pokhara, Nepal from 1st January to 31st December 2015. ResultsIntentional head injury accounted to 17.40% of all head injury cases admitted during the study period. Among them 48 (76.19%) were males and 15 (23.81%) were females. The minimum age of the patient was 15 years and maximum was 84 years with a mean age of 33.89±14.67 years. Most of the victims of physical assault belonged to the age group of 21 to 30 years. Blunt object was the most commonly used for assault. Loss of consciousness was associated only with 49.21% of cases and 14.29% cases had bleeding from ear and/or nose. More than 75% of the cases had significant radiological finding in the form of fracture and/or intracranial lesion. Majority of the victims during the study were treated conservatively and were discharged with advice. Alcohol use was involved in 36.51% cases of intentional head injuries. ConclusionIntentional injuries under the influence of alcohol use are totally preventable public health concerns. It can be ascertained that reducing availability and improving the environment in which alcohol is sold and consumed can result in a dramatic reduction in violent crimes.Birat Journal of Health Sciences Vol.2/No.1/Issue 2/ Jan - April 2017, Page: 102-105

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Role of brain perfusion single-photon emission tomography in traumatic head injury

Nuclear Medicine Communications ◽

10.1097/00006231-200404000-00004 ◽

2004 ◽

Vol 25 (4) ◽

pp. 333-337 ◽

Cited By ~ 20

Author(s):

Keiko Kinuya ◽

Kiyoshi Kakuda ◽

Koji Nobata ◽

Sotaro Sakai ◽

Kenji Yamamoto ◽

...

Keyword(s):

Head Injury ◽

Single Photon ◽

Photon Emission ◽

Brain Perfusion ◽

Emission Tomography ◽

Single Photon Emission ◽

Traumatic Head Injury ◽

Traumatic Head ◽

Photon Emission Tomography

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The Role of Pre-injury IQ in the Determination of Intellectual Impairment From Traumatic Head Injury

Journal of Neuropsychiatry ◽

10.1176/jnp.12.3.385 ◽

2000 ◽

Vol 12 (3) ◽

pp. 385-388 ◽

Cited By ~ 3

Author(s):

Beilin Gao ◽

Shaoai Jiang ◽

Xiaoping Wang ◽

Jingdong Chen

Keyword(s):

Head Injury ◽

Intellectual Impairment ◽

Traumatic Head Injury ◽

Traumatic Head

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The relation between malnutrition screening tool (NUTRIC) score and serum pro- and anti-inflammatory cytokines levels and some nutritional parameters in patients with traumatic head injury in Sulaimani

10.53350/pjmhs211551755 ◽

2021 ◽

Vol 15 (5) ◽

pp. 1755-1759

Author(s):

Shahow Abdulrehman Ezzaddin

Keyword(s):

Head Injury ◽

Inflammatory Cytokines ◽

Screening Tool ◽

Apache Ii ◽

Traumatic Head Injury ◽

Nutritional Parameters ◽

Icu Admission ◽

Serum Cytokines ◽

Traumatic Head ◽

Pro Inflammatory Cytokines

Background: Research has provided evidence that malnutrition screening tool (NUTRIC) score has a relation with interleukin-6 but not with other cytokines. In addition, the relation between malnutrition screening tool (NUTRIC) score and some nutritional parameters has not yet been studied in traumatic head injured patients. Therefore, the aim of the current study is examining the relation between malnutrition screening tool (NUTRIC) score and serum pro- and anti-inflammatory cytokines levels and some nutritional parameters in patients with traumatic head injury in the intensive care unit (ICU) of General Teaching Hospital in Sulaimani, the Kurdistan Region of Iraq in 2016-17. Methods: Using appropriate methods and tools, the patients’ (NUTRIC) score, mid-upper arm circumference (MUAC), disease severity and organ dysfunction, concentration level of serum cytokines (IL-6) were assessed within 24 hours after admission. All of the mentioned measurements except the serum interleukin were also assessed on days 6 and 13 of staying in ICU. Afterwards, in order to examine the relationship between the study’s variables, the collected data were analyzed using Mann-Whitney U test through SPSS 22.0. Results: The results of data analysis using Mann-Whitney U and independent samples T-tests revealed that there was a significant relation between malnutrition screening tool (NUTRIC) score and the studied interleukin (IL-6) within 24 hours after ICU admission. Other studied variables that had a significant association with the patients’ (NUTRIC) score within 24 hours after ICU admission were APACHE II score, SOFA score, and MUAC, this significant association has been seen on days 6 and 13 after ICU admission between malnutrition screening tool (NUTRIC) score and serum cytokines (IL-6) APACHE II, and SOFA scores. Conclusion: The results of the present study revealed that pro-inflammatory cytokines (IL-6) along with other factors such as APACHE II and SOFA had significantly higher among patients with risk of malnutrition. Keywords: pro-inflammatory cytokines, traumatic head injury (THI), nutritional score

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