scholarly journals Neutrophil-to-lymphocyte ratio as a predictor of acute appendicitis

2014 ◽  
Vol 20 (1) ◽  
pp. 19-22 ◽  
Author(s):  
Sahin Kahramanca ◽  
Gulay Ozgehan ◽  
Duray Seker ◽  
Emre Ismail Gokce ◽  
Gaye Seker ◽  
...  
Keyword(s):  
Acute Appendicitis ◽  
Neutrophil To Lymphocyte Ratio ◽  
Lymphocyte Ratio

scholarly journals Evaluation of diagnostic value of neutrophil to lymphocyte ratio in younger and older pediatrics suspect to acute appendicitis in Imam Hossein hospital

2020 ◽  
Vol 5 (2) ◽  
pp. e26-e26
Author(s):  
Azar Baradaran ◽  
Azar Naimi ◽  
Elahe Pirpiran ◽  
Masoud Akhlaghi
Keyword(s):  
Acute Appendicitis ◽  
Sensitivity And Specificity ◽  
Medical Center ◽  
Statistical Tests ◽  
The United States ◽  
Diagnostic Value ◽  
Neutrophil To Lymphocyte Ratio ◽  
Significance Level ◽  
Suspected Appendicitis ◽  
Lymphocyte Ratio

Introduction: Acute appendicitis in children is the most common acute surgical condition in children. Each year, 80000 children in the United States suffer from appendicitis. Objectives: The aim of this study was to evaluate diagnostic value of neutrophil to lymphocyte ratio (NLR) in younger and older pediatrics suspect of acute appendicitis in Imam Hossein hospital. Patients and Methods: This was a retrospective study conducted at Imam Hossein hospital from 2015-2017. The study population was all children with suspected appendicitis who refer to Imam Hossein medical center in Isfahan. The sample size was 423 people. The collected data were imported into SPSS software version 22 and analyzed with appropriate statistical tests. The significance level in the present study was less than 0.05. Results: The average age of participants was 7.2 ± 3.8 years. In both study groups, it was observed that the mean NLR in the normal and reactive follicular groups was significantly lower than the appendicitis and complication groups (P<0.05). The results of the present study showed that NLR diagnostic test can be a good predictor for the evaluation of appendicitis in both groups under 4 years and over 4 years. For more than 4 years’ group; AUC=0.74, P<0.001 and for less than 4 years’ group; AUC=0.69, P<0.001. For less than 4 years’ group, the cut-off score for appendicitis diagnosis was 2.3. In this cut-off, the sensitivity and specificity were equal to 0.65% and 0.72%. Additionally, for more than 4 years’ group, the cut-off for the diagnosis of appendix was 3.5. In this cut-off, the sensitivity and specificity were equal to 0.73% and 67%. Conclusion: This analysis demonstrates that NLR, in the context of appropriate clinical assessment of patients with a high a priori probability of appendicitis, has a greater diagnostic accuracy in supporting the diagnosis of appendicitis.

scholarly journals A Cross-Sectional Study of Neutrophil-to-Lymphocyte Ratio in Diagnosing Acute Appendicitis in Hospital Melaka

2019 ◽  
Vol 26 (6) ◽  
pp. 55-66
Author(s):  
Khairol Ashraf Ahmad ◽  
◽  
Noorharisman Ideris ◽  
Syed Hassan Syed Abd Aziz ◽  
◽  
...  
Keyword(s):  
Acute Appendicitis ◽  
Cross Sectional Study ◽  
Neutrophil To Lymphocyte Ratio ◽  
Sectional Study ◽  
Cross Sectional ◽  
Lymphocyte Ratio

scholarly journals Neutrophil-to-lymphocyte ratio in pediatric acute appendicitis

2018 ◽  
Vol 75 (1) ◽  
pp. 46-55 ◽  
Author(s):  
Nikola Stankovic ◽  
Ivan Stanojevic ◽  
Dragan Djordjevic ◽  
Zoran Kostic ◽  
Ivo Udovicic ◽  
...  
Keyword(s):  
Acute Appendicitis ◽  
Clinical History ◽  
Neutrophil To Lymphocyte Ratio ◽  
Strong Positive Correlation ◽  
Strong Negative Correlation ◽  
Lymphocyte Ratio ◽  
Reactive Protein ◽  
Mother And Child ◽  
Child Healthcare

Background/Aim. Acute appendicitis (AA) is the most frequent emergency and appendectomy is the most frequent abdominal operation in the pediatric surgery. Diagnosis of AA in children is more difficult due to a lack of cooperation and poor clinical history data, leading to significant number of misdiagnostic cases. Our aim was to explore whether neutrophil to lymphocyte ratio (NLR) may be useful in diagnosis and follow-up of AA in children. Methods. Prospective investigation of NLR values in 129 consecutive patients admitted to the Mother and Child Healthcare Institute of Serbia and referred for surgery due to AA was performed. According to the pathohistological findings, patients were divided into 3 groups: normal/early, uncomplicated (phlegmonous) and complicated (gangrenous or/and perforated) AA. Laboratory analysis was done preoperativly and on the 1st and the 3rd postoperative days. Results. Statistically significant differences of NLR values were found in the different time points in total of patients and per groups. Some statistically significant differences of NLR values among histopathological groups were recorded. Investigations of correlation of NLR and other laboratory and clinical parameters showed strong positive correlation between NLR and C-reactive protein postoperatively and between NLR and Pediatric Appendicitis Score (PAS) preoperatively. Strong negative correlation with preoperative symptoms duration (PSD) were also present. Optimal cutoff NLR value between negative and positive appendectomies was 6.14. Conclusion. NLR provides well monitoring of progression of AA in children and, its cutoff values may help in distinguishing the phases of AA. Because of that, NLR should be used in diagnosis of AA in children.

scholarly journals Could the neutrophil-to-lymphocyte ratio serve as a marker in the diagnosis and prediction of acute appendicitis complications in children?

2019 ◽  
Author(s):  
Sadeta Begic-Kapetanovic ◽  
Nesina Avdagic ◽  
Asija Zaciragic ◽  
Sabaheta Hasic ◽  
Nermina Babic ◽  
...  
Keyword(s):  
Acute Appendicitis ◽  
Neutrophil To Lymphocyte Ratio ◽  
Lymphocyte Ratio

Prospective validation of neutrophil-to-lymphocyte ratio as a diagnostic and management adjunct in acute appendicitis

2017 ◽  
Vol 187 (2) ◽  
pp. 379-384 ◽  
Author(s):  
A. Khan ◽  
M. Riaz ◽  
Michael E. Kelly ◽  
W. Khan ◽  
R. Waldron ◽  
...  
Keyword(s):  
Acute Appendicitis ◽  
Neutrophil To Lymphocyte Ratio ◽  
Lymphocyte Ratio

scholarly journals EP.FRI.477 Neutrophil-To-Lymphocyte Ratio (NLR) as a Predictor of Acute Appendicitis

2021 ◽  
Vol 108 (Supplement_7) ◽  
Author(s):  
Sadia Tasleem ◽  
Nadia Gulnaz
Keyword(s):  
Acute Appendicitis ◽  
Diagnostic Accuracy ◽  
Gold Standard ◽  
Complicated Appendicitis ◽  
Neutrophil To Lymphocyte Ratio ◽  
College Hospital ◽  
Duration Of Symptoms ◽  
Lymphocyte Ratio ◽  
Study Results ◽  
Sensitivity Specificity

Abstract The most common reason for an acute surgical assessment of the abdomen is acute appendicitis with a rate as high as 30 %There is a   lifetime risk of 8.6% and 6.7% in men and women respectively. The common age for presentation is between that of 5 and 4.4 while 28 is the median age. The objective of this study was to determine   the diagnostic accuracy   of (NLR) neutrophil-to-lymphocyte ratio to prognosticate severe/ complicated appendicitis by taking histopathology of the appendix as a gold standard. Methodology This cross-sectional validation study was conducted at the department of surgery and western vascular institute, University College Hospital Galway, Ireland retrospectively for a period of 6 months in 2016 And approximately 186 cases with appendicitis were enrolled in the study. Results The mean age of patients in this study was 29.15±9.54 years, the ratio of male to female was 1:1.7.   The sensitivity, Specificity was 97.1% and   25.2% respectively and the diagnostic accuracy of NLR was 38.7% taking histopathology as the gold standard. We observed that the sensitivity, specificity, and diagnostic accuracy of NLR   changes with the duration of symptoms in days, the sensitivity, specificity, and diagnostic accuracy of NLR was 100%, 17.0%, and 28.7%    respectively for &lt;3days   and 92.3%, 93.75% and93.1% respectively for &gt;3 days. Conclusion According to our study results the (NLR) neutrophil-to-lymphocyte ratio is a highly sensitive tool to predict severe/   complicated appendicitis by taking histopathology as the gold standard, but with the low value of diagnostic accuracy in terms of specificity.

scholarly journals Neutrophil to lymphocyte ratio as the marker of acute appendicitis and its destructive forms in children

2020 ◽  
pp. 35-40
Author(s):  
A.A. Pereyaslov ◽  
◽  
A.I. Bobak ◽  
O.M. Nykyforuk ◽  
R.V. Stenyk ◽  
...  
Keyword(s):  
Acute Appendicitis ◽  
Neutrophil To Lymphocyte Ratio ◽  
Lymphocyte Ratio
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