Effect of Cypermethrin Induced Antioxidant Enzymes Systems in Response to Melatonin Administration in Drosophila Melanogaster

2016 ◽  
Vol 6 (2) ◽  
pp. 167-172
Author(s):  
Selvaraj Vasuki ◽  
Sengodan Karthi ◽  
Muthugoundar Subramanian Shivakumar
Keyword(s):  
Drosophila Melanogaster ◽  
Antioxidant Enzymes ◽  
Melatonin Administration

Pro-oxidant activity of aluminum in the rat hippocampus: gene expression of antioxidant enzymes after melatonin administration

2005 ◽  
Vol 38 (1) ◽  
pp. 104-111 ◽  
Author(s):  
Mercedes Gómez ◽  
José L. Esparza ◽  
M. Rosa Nogués ◽  
Montserrat Giralt ◽  
Maria Cabré ◽  
...  
Keyword(s):  
Gene Expression ◽  
Antioxidant Enzymes ◽  
Rat Hippocampus ◽  
Melatonin Administration

scholarly journals The effects of melatonin treatment on oxidative stress induced by ovariohysterectomy in dogs

2021 ◽  
Vol 17 (1) ◽  
Author(s):  
Sina Salavati ◽  
Asghar Mogheiseh ◽  
Saeed Nazifi ◽  
Atefeh Amiri ◽  
Behrooz Nikahval
Keyword(s):  
Oxidative Stress ◽  
Antioxidant Enzymes ◽  
Antioxidant Properties ◽  
Mature Female ◽  
Control Group ◽  
Melatonin Treatment ◽  
Melatonin Administration ◽  
Before And After ◽  
Commercial Kits ◽  
And Control

Abstract Background As one of the most common surgeries performed in veterinary medicine, ovariohysterectomy (OHE) can induce oxidative stress in dogs. The antioxidant properties of melatonin have been confirmed in various studies. This study aimed to investigate the effects of melatonin administration on oxidative stress in dogs before and after OHE. In this study, 25 mature female intact dogs were selected and randomly divided into five equal groups: Melatonin (melatonin, no surgery), OHE (no melatonin, surgery), OHE + melatonin (melatonin, surgery), anesthesia+melatonin (melatonin, sham surgery), and control (no melatonin, no surgery) groups. Melatonin (0.3 mg/Kg/day, p.o.) was administrated to the dogs in the melatonin, OHE + melatonin, and anesthesia+melatonin groups on days − 1, 0, 1, 2, and 3 (day 0 = OHE). Blood sampling was performed on days − 1, 1, 3, and 5 of the study. Blood samples were immediately transferred to the laboratory and sera were separated and stored at − 20 °C. Superoxide dismutase (SOD), glutathione peroxidase (GPX), catalase (CAT) and malondialdehyde (MDA) concentrations were measured with commercial kits. Results The levels of SOD, GPX and CAT were significantly higher in the melatonin and anesthesia+melatonin groups compared to those of the control group at days 3 and 5. The level of antioxidant enzymes significantly decreased in the OHE group compared to that of other groups at days 3 and 5. The administration of melatonin increased the level of antioxidant enzymes in ovariohysterectomized dogs. Ovariohysterectomy significantly increased the concentration of MDA in comparison to that of other groups at day 3. Melatonin administration significantly decreased the level of MDA in melatonin, anesthetized, and ovariohysterectomized dogs at day 3. Conclusions Administration of melatonin on day − 1, 0, 1, 2 and 3 modulate the oxidative stress induced by OHE in dogs by increasing antioxidant enzymes concentration and decreasing MDA levels.

scholarly journals The Effects of Melatonin Treatment on Oxidative Stress Induced by Ovariohysterectomy in Dogs

2020 ◽  
Author(s):  
Sina Salavati ◽  
Asghar Mogheiseh ◽  
Saeed Nazifi ◽  
Atefeh Amiri ◽  
Behrooz Nikahval
Keyword(s):  
Oxidative Stress ◽  
Antioxidant Enzymes ◽  
Antioxidant Properties ◽  
Mature Female ◽  
Control Group ◽  
Control Groups ◽  
Melatonin Treatment ◽  
Melatonin Administration ◽  
Before And After ◽  
And Control

Abstract Background: As one of the most common surgeries performed in veterinary medicine, ovariohysterectomy (OHE) can induce stress in dogs. The antioxidant properties of melatonin have been confirmed in various studies. This study aimed to investigate the effects of melatonin administration on oxidative stress in dogs before and after OHE. In this study, 25 mature female intact dogs were selected and randomly divided into five equal groups: Melatonin, OHE, melatonin+OHE+melatonin, melatonin+anesthesia+melatonin, and control groups. Melatonin (0.3 mg/Kg/day, p.o.) was administrated to the dogs in the melatonin, melatonin+OHE+melatonin, and melatonin+anesthesia+melatonin groups on days -1, 1, 2, and 3 (day 0=OHE). Blood sampling was performed on days -1, 1, 3, and 5 of the study. Blood samples were immediately transferred to the laboratory and sera were separated and stored at -20 °C. Superoxide dismutase (SOD), glutathione peroxidase (GPX), and catalase (CAT) concentrations were significantly higher in the melatonin and melatonin+anesthesia+melatonin groups compared to those of the control group. Results: The level of antioxidant enzymes significantly decreased in the OHE group compared to that of other groups. The administration of melatonin increased the level of antioxidant enzymes in ovariohysterectomized dogs. OHE significantly increased the concentration of malondialdehyde (MDA) in comparison to that of other groups. Melatonin administration significantly decreased the level of MDA in intact, anesthetized, and ovariohysterectomized dogs. Conclusions: It can be stated that the administration of melatonin one day before and during one week after OHE could control oxidative stress in dogs with increased antioxidant enzymes and decreased MDA levels.

Curcumin-supplemented diets improve antioxidant enzymes and alter acetylcholinesterase genes expression level in Drosophila melanogaster model

2017 ◽  
Vol 33 (2) ◽  
pp. 369-375 ◽  
Author(s):  
Ayodele Jacob Akinyemi ◽  
Ganiyu Oboh ◽  
Opeyemi Ogunsuyi ◽  
Amos Olalekan Abolaji ◽  
Adetutu Udofia
Keyword(s):  
Drosophila Melanogaster ◽  
Antioxidant Enzymes ◽  
Expression Level ◽  
Genes Expression
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