A Prospective Observational Study on Evaluation of Chemotherapy Induced Adverse Drug Reactions in Cancer Patients in a Tertiary Care Hospital

2021 ◽  
Vol 14 (1) ◽  
pp. 2-8
Author(s):  
Priya Saji Koliyakodu ◽  
Rona Sudhakar ◽  
Manesh Mathews Kurian ◽  
Jishnu Jishnu R K ◽  
Raj Kumar ◽  
...  
2020 ◽  
Vol 11 (SPL4) ◽  
pp. 2669-2674
Author(s):  
Dona Thomas ◽  
Sharon Thomas ◽  
Venkateswaramurthy N ◽  
Sambathkumar R

The study was aimed to analyse the pattern of medication errors and drug interaction induced adverse drug reactions in the psychiatry department of a tertiary care hospital. A Prospective observational study being conducted in the inpatient and outpatient department of psychiatry in a tertiary care hospital, Erode, Tamil Nadu for over six months. A total of 80 prescriptions with psychiatric illness and 174 medication errors were observed. Of the 174 medication errors observed, 132(75.8%) were incomplete prescriptions making the highest number of medication errors. The highest number of errors occurred due to Prescription error 156(89.0%), followed by administration error 8(4.5%). According to the NCCMERP classification, the majority of medication errors were coming under category B 120(68.9%) but there is no harm. The demographic reports of outpatients in the present study showed a higher incidence of medication errors in patients with the age group of 31-40 years 25(36.7%). Considering the factors contributing to a medication error, refusal of the patient to take the drug 27(39.7%) followed by forgetting 13(19.1%) due to the vulnerable characteristics of the patient was more significant. Although there is a general lack of awareness, many patients and bystanders are unaware of their diagnosis and medications. It is, therefore, a crucial step to educate and make them aware of the correct use of medicine.


2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Syed Afzaluddin Biyabani ◽  
Mohammed Irfan Ali ◽  
Syed Raziuddin Faisal ◽  
Syed Iqbal Pasha ◽  
Javed Akhtar Ansari ◽  
...  

2017 ◽  
Vol 9 (4) ◽  
pp. 593-597 ◽  
Author(s):  
Sapan Kumar Behera ◽  
Chenchu Reddy Kishtapati ◽  
Vikneswaran Gunaseelan ◽  
Biswajit Dubashi ◽  
Adithan Chandrasekaran ◽  
...  

Author(s):  
Sowmya M. S. ◽  
Basavanna P. L. ◽  
L. Raghavendra Gupta

Background: Cancer is a multi-cellular disease which can arise from any cell type and organs. Adverse drug reactions (ADR) are undesirable consequence of cancer chemotherapeutic drugs. A great importance has to be given for their assessment, detection, monitoring, reporting and preventing these ADR for the beneficial effects of the patients. So the present study was undertaken for the purpose of detecting and quantifying those adverse reactions which is of some importance in therapeutic setting.Methods: A prospective observational study conducted in chemotherapy ward, male and female patients of any age receiving cancer chemotherapy and presenting with ADR’s in duration of 3 months.Results: 160 patients were observed. Out of 160 patients 123 presented with ADR’s. Most common ADR’s were loss of appetite (67.6), diarrhea (61.8%), vomiting (21.5%), nausea (17.7%), anemia (24.7%). Cisplatin, paclitaxel, oxaliplatin, doxorubicin, gefitinib are common drugs causing ADR’s.Conclusions: Cancer chemotherapeutic drugs are associated with various adverse reactions. This study shows the importance of active monitoring of these reactions and measures to prevent their effects early in the treatment of cancer.


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