scholarly journals Cleaner and Efficient Green Chemistry Synthesis of N,N´-Dibenzyl or N,N´-(2-Hydroxybenzyl)-Ethane-1,2-Diamine,-Propane-1,3-Diamine and -1,3-Diamino-2-Propanol

2016 ◽  
Vol 8 (4) ◽  
pp. 62 ◽  
Author(s):  
Augusto Rivera ◽  
Ingrid Miranda-Carvajal ◽  
Jaime Ríos-Motta
Keyword(s):  
Green Chemistry ◽  
Schiff Bases ◽  
Sodium Borohydride ◽  
Good Yield ◽  
Solvent Free ◽  
Mild Conditions ◽  
Excellent Yield ◽  
High Yields ◽  
Work Up

<p>An efficient and highly eco-friendly protocol for the preparation of <em>N,N´</em>-dibenzyl or <em>N,N´</em>-(2-hydroxybenzyl)diamines via the reduction of the corresponding di-Schiff bases that produces a good yield using water as a solvent without the need for catalysis or the azeotropic removal of water has been developed. These symmetric diimines have been reduced to their corresponding diamines with sodium borohydride using a catalyst- and solvent-free protocol with excellent yield. Mild conditions, high yields, and a simple work-up procedure are the primary benefits of this protocol.</p>

scholarly journals Green-chemistry Compatible Approach to TiO2-supported PdAu Bimetallic Nanoparticles for Solvent-free 1-Phenylethanol Oxidation under Mild Conditions

2015 ◽  
Vol 7 (3) ◽  
pp. 307-315 ◽  
Author(s):  
Jian-Bing Chang ◽  
Chang-Hai Liu ◽  
Jie Liu ◽  
Yu-Yan Zhou ◽  
Xu Gao ◽  
...  
Keyword(s):  
Green Chemistry ◽  
Bimetallic Nanoparticles ◽  
Solvent Free ◽  
Mild Conditions

Rapid and Green One-Pot Synthesis of Novel 2-(4-Hydroxy-2-oxo-2H-chromen-3-yl)-2-(arylamino)-1H-indene-1,3(2H)-diones

2021 ◽  
Vol 18 ◽  
Author(s):  
Abolfazl Olyaei ◽  
Zahra Ghahremany ◽  
Madieh Sadeghpour
Keyword(s):  
Aromatic Amines ◽  
Low Cost ◽  
Guanidine Hydrochloride ◽  
Reaction Times ◽  
Solvent Free ◽  
One Pot ◽  
Solvent Free Conditions ◽  
The One ◽  
High Yields ◽  
Work Up

: A green and efficient protocol was developed for the one-pot three-component synthesis of novel 2-(4-hydroxy-2-oxo-2H-chromen-3-yl)-2-(arylamino)-1H-indene-1,3(2H)-dione derivatives by the reaction of 4-hydroxycoumarin, ninhydrin and aromatic amines in the presence of guanidine hydrochloride as an organocatalyst under solvent-free conditions. The present approach offers several advantages such as low cost, simple work-up, short reaction times, chromatography-free purification, high yields and greener conditions.

scholarly journals A Solvent-Free Protocol for the Green Synthesis of 5-Arylidene-2,4-thiazolidinediones Using Ethylenediamine Diacetate as Catalyst

2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Yuliang Zhang ◽  
Zhongqiang Zhou
Keyword(s):  
Knoevenagel Condensation ◽  
Aromatic Aldehydes ◽  
Solvent Free ◽  
Reusable Catalyst ◽  
Efficient Synthesis ◽  
Reaction Conditions ◽  
Solvent Free Conditions ◽  
High Yields ◽  
Work Up ◽  
Solvent Free Reaction

A simple and efficient synthesis of 5-arylidene-2,4-thiazolidinediones by the Knoevenagel condensation of aromatic aldehydes with 2,4-thiazolidinedione catalyzed by ethylenediamine diacetate under solvent-free conditions is described. The major advantages of this method are simple experimental and work-up procedures, solvent-free reaction conditions, small amount of catalyst, short reaction time, high yields, and utilization of an inexpensive and reusable catalyst.

Synthesis of Novel 3-(Benzothiazol-2-Ylmethylene)Indolin-2-Ones

2017 ◽  
Vol 41 (9) ◽  
pp. 537-540
Author(s):  
Chao Zhang ◽  
Juan Xu ◽  
Xinyu Zhao ◽  
Congmin Kang
Keyword(s):  
Aldol Condensation ◽  
Mild Conditions ◽  
High Yields ◽  
Work Up

A mild method for the synthesis of 3-(benzothiazol-2-ylmethylene)indolin-2-ones via the aldol condensation of substituted indolin-2-ones and benzothiazole-2-carbaldehyde is described. This new procedure has significant advantages, such as mild conditions, high yields and simple work-up.

scholarly journals SOLVENT-FREE SYNTHESIS OF AMIDE: A NOVEL TECHNIQUE OF GREEN CHEMISTRY

2021 ◽  
pp. 99-102
Author(s):  
CHIRAGKUMAR J GOHIL ◽  
MALLESHAPPA N NOOLVI
Keyword(s):  
Carboxylic Acid ◽  
Green Chemistry ◽  
Good Yield ◽  
Functional Group ◽  
Environmental Issues ◽  
Solvent Free ◽  
Novel Technique ◽  
Rate Of Reaction ◽  
Solvent Free Synthesis ◽  
Very High

Objective: Amide is one of the most important functional group presents in the chemicals, pharmaceuticals, and foods. Conventionally, it has been synthesized from the carboxylic acid and amines. This conventional reaction is lengthy and involves hazardous chemicals and solvents. Hence, it poses waste management, solvent removal, and environmental issues to the industries. To overcome this limitation, we have reported the green chemistry-based method for the synthesis of amide from carboxylic acid and urea. Methods: In this reaction, we have used boric acid as a catalyst, it is a simple and readily available compound. It is simple, efficient, and solvent-free procedure which involves the trituration of the reactant mixture and subsequent, direct heating of the triturated mixture. Results: The rate of reaction is very high and can synthesize the amide quickly. Conclusion: Various amides were prepared in good yield by this technique.

Oxokohlenstoffe und verwandte Verbindungen. 32 [1]. Über die Umsetzung von Quadratsäuredichlorid und Perchlorcyclobutenon mit SchiffBasen

2008 ◽  
Vol 63 (7) ◽  
pp. 1-7
Author(s):  
Arthur H. Schmidt ◽  
Peter Müllen ◽  
Gabriele Wallmeyer ◽  
Claudia Plutniok ◽  
Peter R. Wiesert
Keyword(s):  
Schiff Bases ◽  
Good Yield ◽  
Mild Conditions ◽  
Hydrolysis Of

Squaric dichloride (3) reacts with Schiff bases 5 under mild conditions to give 1 : 1 adducts 7. On recrystallisation from alcohols, these adducts are converted to the respective N-(α-alkoxybenzyl)- squaric amide chlorides 8. The reaction has been extended to perchlorocyclobutenone 4. Thus, addition products 14 have been obtained from the reaction of 4 with Schiff bases 5, which, on recrystallisation from alcohols, afforded N-(α-alkoxybenzyl)-substituted 3-amino-2,4,4-trichloro-cyclobuten- 1-ones 15. Hydrolysis of the adducts 14 gave the aminotrichlorocyclobutenones 17 in good yield.

scholarly journals An Efficient and Green Procedure for the Synthesis of 2,4,6-Triarylpyridines Using PPA-SiO2as a Reusable Heterogeneous Catalyst Under Solvent-Free Conditions

2012 ◽  
Vol 9 (4) ◽  
pp. 2037-2043 ◽  
Author(s):  
Abolghasem Davoodnia ◽  
Bahareh Razavi ◽  
Niloofar Tavakoli-Hoseini
Keyword(s):  
Heterogeneous Catalyst ◽  
Simple Procedure ◽  
Substantial Reduction ◽  
Reaction Times ◽  
Solvent Free ◽  
One Pot ◽  
Solvent Free Conditions ◽  
Three Component Reaction ◽  
High Yields ◽  
Work Up

Silica gel-supported polyphosphoric acid (PPA-SiO2) was found to be highly efficient, eco-friendly and recyclable heterogeneous catalyst for the synthesis of 2,4,6-triarylpyridines through one-pot three-component reaction of acetophenone, aryl aldehydes, and ammonium acetate under solvent-free conditions. This method has several advantages, such as simple procedure with an easy work-up, short reaction times, and high yields. Furthermore, the catalyst could be recycled after a simple work-up, and used at least three times without substantial reduction in its catalytic activity.

scholarly journals An Efficient One-Pot Synthesis of 1, 5-Benzodiazepine Derivatives Catalyzed by TBAB under Mild Conditions

2012 ◽  
Vol 9 (1) ◽  
pp. 407-414 ◽  
Author(s):  
Mohammad A. Baseer ◽  
Asgar Jafar Khan
Keyword(s):  
Reaction Time ◽  
Solvent Free ◽  
Ammonium Bromide ◽  
One Pot ◽  
Short Reaction Time ◽  
Mild Conditions ◽  
Excellent Yield ◽  
One Pot Synthesis ◽  
Solvent Free Conditions ◽  
Benzodiazepine Derivatives

2,3-Dihydro-1H-1,5-benzodiazepines were synthesized by reaction ofo-phenylenediamine with ketones (acyclic / cyclic) under solvent free conditions in the presence of tetra butyl ammonium bromide (TBAB) in short reaction time with excellent yield.

Coaled Carbon-Based Solid Acid: a New and Efficient Catalyst for Click Synthesis of 3,4-Dihydropyrimidin-2(1H)-Ones under Solvent-Free Conditions

2013 ◽  
Vol 634-638 ◽  
pp. 504-507
Author(s):  
Wan Yi Liu ◽  
Ning Liu ◽  
Rui Yuan Zheng ◽  
Bing Li ◽  
Xia Zhang ◽  
...  
Keyword(s):  
Solid Acid ◽  
Reaction Times ◽  
Solvent Free ◽  
Multicomponent Synthesis ◽  
Efficient Catalyst ◽  
Solvent Free Conditions ◽  
Important Addition ◽  
High Yields ◽  
Work Up ◽  
Carbon Based

Coaled carbon-based solid acid (CCBSAC) is reported as a new, efficient and recyclable catalyst for the regioselective multicomponent synthesis of dihydropyrimidin-2(1H)-ones from aldehydes, β-ketoesters and urea or thiourea under solvent-free conditions. The structure and thermal stability of CCBSAC which resulted from ultra-clean coal resources mainly were characterized by IR, XRD, and TG. Nineteen dihydropyrimidin-2(1H)-ones examples were prepared and this catalyst could recycle up to 4 consecutive runs without losing its efficiency. The high yields of products, short reaction times, ease of work-up and clean procedure will make the present method a useful and important addition to the previous methodologies for the synthesis of dihydropyrimidin-2(1H)-ones.

A highly effective and mild protocol for the production of 1-thioamidoalkyl-2-naphthols using 1,3-disulfonic acid imidazolium trifluoroacetate as a dual-functional catalyst

2018 ◽  
Vol 73 (5) ◽  
pp. 289-293 ◽  
Author(s):  
Mostafa Karami ◽  
Abdolkarim Zare
Keyword(s):  
Ionic Liquid ◽  
Reaction Time ◽  
Reaction Times ◽  
Solvent Free ◽  
Disulfonic Acid ◽  
One Pot ◽  
Mild Conditions ◽  
Dual Functional ◽  
Highly Effective ◽  
High Yields

AbstractA solvent-free protocol for the production of 1-thioamidoalkyl-2-naphthols via a one-pot multi-component reaction of arylaldehydes with 2-naphthol and thioacetamide using the ionic liquid 1,3-disulfonic acid imidazolium trifluoroacetate ([Dsim][TFA]) is described. Furthermore, a plausible and attractive mechanism based on the dual functionality of the catalyst is proposed. Because of the dual functionality of [Dsim][TFA] (possessing acidic and basic sites), it is found to be generally highly effective, affording the products in high yields and short reaction times under mild conditions. We claim that this is one of the best protocols for the synthesis of 1-thioamidoalkyl-2-naphthols (in terms of yield, temperature, conditions, and/or the reaction time).

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