. In order to obtain suitable titanium mesh MEA (membrane electrode assembly) for direct methanol fuel cell (DMFC) molding temperature conditions, titanium mesh was used as electrode substrate material, Nafion 117 membrane was used as proton exchange membrane, PtRu/XC-72R and Pt/XC-72R were used as anode catalyst and cathode catalyst respectively, anode and cathode of titanium mesh MEA were prepared by drop-coating method. When the MEAs were molded by hot-pressing under 5 MPa for 180 s with different temperatures of 115°C, 135°C and 155°C, respectively, the maximum power density of Ti mesh-based MEAs increases firstly, after the first peak, it gradually decreases along with the increase of molding pressure conditions, and the maximum power density appears at the molding temperature of 135°C, so conclude that molding temperature of 135°C is more appropriate for making the titanium mesh MEA.