Analgesic activities of fractions of Stereospermum kunthianum stem bark.

10.5580/20ae ◽  
2010 ◽  
Vol 8 (1) ◽  
Keyword(s):  
Stem Bark ◽  
Analgesic Activities

scholarly journals Investigation of the Anti-Inflammatory and Analgesic Activities of Ethanol Extract of Stem Bark of SonapathaOroxylum indicum In Vivo

2016 ◽  
Vol 2016 ◽  
pp. 1-8 ◽  
Author(s):  
K. Lalrinzuali ◽  
M. Vabeiryureilai ◽  
Ganesh Chandra Jagetia
Keyword(s):  
Inflammatory Diseases ◽  
Ethanol Extract ◽  
Stem Bark ◽  
The Body ◽  
Protective Measure ◽  
Analgesic Effects ◽  
Oroxylum Indicum ◽  
Anti Inflammatory ◽  
Analgesic Activities

Inflammation is all a pervasive phenomenon, which is elicited by the body in response to obnoxious stimuli as a protective measure. However, sustained inflammation leads to several diseases including cancer. Therefore it is necessary to neutralize inflammation. Sonapatha (Oroxylum indicum), a medicinal plant, is traditionally used as a medicine in Ayurveda and other folk systems of medicine. It is commonly used to treat inflammatory diseases including rheumatoid arthritis and asthma. Despite this fact its anti-inflammatory and analgesic effects are not evaluated scientifically. Therefore, the anti-inflammatory and analgesic activities of Sonapatha (Oroxylum indicum) were studied in Swiss albino mice by different methods. The hot plate, acetic acid, and tail immersion tests were used to evaluate the analgesic activity whereas xylene-induced ear edema and formalin induced paw edema tests were used to study the anti-inflammatory activity of Sonapatha. The administration of mice with 250 and 300 mg/kg b.wt. ofO. indicumreduced pain and inflammation indicating that Sonapatha possesses analgesic and anti-inflammatory activities. The maximum analgesic and anti-inflammatory activities were observed in mice receiving 300 mg/kg b.wt. ofO. indicumethanol extract.Our study indicates thatO. indicumpossesses both anti-inflammatory and analgesic activities and it may be useful as an anti-inflammatory agent in the inflammation related disorders.

Anti-inflammatory and analgesic activities of the ethanolic extracts fromZanthoxylum riedelianum(Rutaceae) leaves and stem bark

2007 ◽  
Vol 59 (8) ◽  
pp. 1151-1158 ◽  
Author(s):  
Leonardo Mandalho Lima ◽  
Fábio Ferreira Perazzo ◽  
José Carlos Tavares Carvalho ◽  
Jairo Kenupp Bastos
Keyword(s):  
Stem Bark ◽  
Ethanolic Extracts ◽  
Anti Inflammatory ◽  
Analgesic Activities

scholarly journals Anti-inflammatory and Analgesic Activities of the Crude Extracts from Stem Bark of Bauhinia Guianensis

1999 ◽  
Vol 37 (4) ◽  
pp. 281-284 ◽  
Author(s):  
J.C.T. Carvalho ◽  
L.S. Santos ◽  
E.P. Viana ◽  
S.S.M.S. de Almeida ◽  
E. Marconato ◽  
...  
Keyword(s):  
Stem Bark ◽  
Crude Extracts ◽  
Anti Inflammatory ◽  
Analgesic Activities

Investigations on anti-inflammatory and analgesic activities of Alnus nitida Spach (Endl). stem bark in Sprague Dawley rats

2017 ◽  
Vol 198 ◽  
pp. 407-416 ◽  
Author(s):  
Moniba Sajid ◽  
Muhammad Rashid Khan ◽  
Sayed Afzal Shah ◽  
Muhammad Majid ◽  
Hammad Ismail ◽  
...  
Keyword(s):  
Stem Bark ◽  
Sprague Dawley ◽  
Sprague Dawley Rats ◽  
Anti Inflammatory ◽  
Analgesic Activities

Department of Pharmaceutical Care, General Hospital of Chinese PLA, Beijing, 100853, P. R. China

2012 ◽  
Vol 67 (7-8) ◽  
pp. 353-359
Author(s):  
Assem El-Shazly ◽  
Afaf El-Sayed ◽  
Eman Fikrey
Keyword(s):  
Methanolic Extract ◽  
Diclofenac Sodium ◽  
Radical Scavenging ◽  
Ethyl Acetate Fraction ◽  
2D Nmr ◽  
Stem Bark ◽  
Free Radical Scavenging ◽  
Light Petroleum ◽  
Paw Oedema ◽  
Analgesic Activities

Column chromatography of the light petroleum fraction from the methanolic extract of the stem bark of Salix tetrasperma Roxb. (Salicaceae) resulted in the isolation of β-sitosterol acetate, friedelin, 3β-friedelinol, β-amyrin, β-sitosterol, β-sitosterol-O-glucoside in addition to palmitic acid. From the dichloromethane fraction of the leaves, catechol and tremulacin were isolated. Salicin and its derivatives tremuloidin and 2’-O-p-(E)-coumaroyl salicin were isolated from the ethyl acetate fraction of the leaves. The isolated compounds were identified by MS, and 1D NMR (1H and 13C) and 2D NMR (H-H COSY, HSQC, and HMBC) spectral analyses. The total methanolic extract exhibited significant anti-inflammatory activity (rat hind paw oedema). The extract with a content of 120 mg/kg body weight produced 52% inhibition equivalent to the standard diclofenac sodium (54% inhibition). The antioxidant (DPPH free radical scavenging) and analgesic activities, respectively, were also evaluated.

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