Cardioprotective Potential Of Vernonia Amygdalina And Ocimum Gratissimum Against Streptozotocin (Stz) – Induced Diabetes In Wistar Rats.

10.5580/907 ◽  
2010 ◽  
Vol 7 (1) ◽  
Keyword(s):  
Wistar Rats ◽  
Vernonia Amygdalina ◽  
Ocimum Gratissimum

Ocimum gratissimum enhances insulin sensitivity in male Wistar rats with dexamethasone-induced insulin resistance

2021 ◽  
Author(s):  
Shehu-Tijani Toyin Shittu ◽  
Taye Jemilat Lasisi ◽  
Seyid Alli-Sisse Shittu ◽  
Adeyinka Adeyemi ◽  
Tolulope James Adeoye ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Insulin Sensitivity ◽  
Wistar Rats ◽  
Ocimum Gratissimum ◽  
Male Wistar Rats

Subacute effect of Vernonia amygdalina methanolic crude leaf extract on the hematological profile in albino Wistar rats

2013 ◽  
Vol 1 (1) ◽  
pp. 43
Author(s):  
Thomas Nubila ◽  
NkoyoImelda Nubila ◽  
Ayodele Ukaejiofo ◽  
ElvisNeba Shu ◽  
ChukwubuzorU Okwuosa ◽  
...  
Keyword(s):  
Wistar Rats ◽  
Leaf Extract ◽  
Vernonia Amygdalina ◽  
Hematological Profile ◽  
Crude Leaf Extract

Comparative Antioxidant Activities of Extracts of Vernonia amygdalina and Ocimum gratissimum Leaves

2013 ◽  
Vol 6 (1) ◽  
Author(s):  
Kelly Oriakhi ◽  
Ehigbai Igbuan Oikeh ◽  
Nkeiruka Ezeugwu ◽  
Ogechukwu Anoliefo ◽  
Omorede Aguebor ◽  
...  
Keyword(s):  
Antioxidant Activities ◽  
Vernonia Amygdalina ◽  
Ocimum Gratissimum

Biochemical effect of varied mixtures of extracts of Vernonia amygdalina (bitter leaf) and Gnetum africanum (Okazi leaf) on alloxan induced diabetic wistar rats

2021 ◽  
Vol 20 (1) ◽  
pp. 17-30
Author(s):  
M.O. Ifeanacho ◽  
R.B Oshotse
Keyword(s):  
Diabetes Mellitus ◽  
Wistar Rats ◽  
Treated Group ◽  
The Body ◽  
Blood Protein ◽  
Steady Increase ◽  
Vernonia Amygdalina ◽  
Leaf Extracts ◽  
Biochemical Effect ◽  
Total Blood

Diabetes mellitus is prevalent in many countries of the world, affecting all ages both in developing and developed nations. The use of plants as remedies or preventive therapies has increased over the years. The study investigated the biochemical changes caused by  combined leaf extracts of Vernonia amygdalina (bitter leaf) and Gnetum africanum (okazi leaf) on alloxan induced diabetic wistar rats.Aqueous extracts of the leaves were prepared using the conventional method.Forty male wistar rats weighing 150-180g were  grouped into eight (five rats each). Group 1 was the normal control while diabetes was induced using alloxan (160mg/ kg)in groups 2-8.Group 2 received no treatment while groups 3-7 received varied ratios of the extracts at (BI/OK|10:90%), (BI/OK|30:70%),  (BI/OK|50:50%), (BI/OK|70:30%) and (BI/OK|90:10%). Group 8 was the diabetic control treated with the standard diabetic drug (Metformin). The animals were weighed and blood glucose was determined at 7-day intervals. They were sacrificed on the 28th day and blood samples collected for serum protein, serum electrolyte, urea, creatinine, liver enzymes and markers of oxidative stress analyses.  The results showed steady increase in the body weights (g) of the rats with (BI/OK|70:30)% treated group showing the highest increase (175.40±1.28). The fasting blood sugar (mg/dl) showed timedependent reduction in all the treated diabeti groups with (BI/OK|90:10)% having the highest (56.20±1.65) reduction. There was a significant increase (p<0.05) in total blood protein concentration (g/dl) in all the treated groups. The results of this study showed time and ratio dependent effect on the parameters measured. Since the two plants are staple vegetables in some countries, their utilization particularly in appropriate combinations should be encouraged. Key words: Extracts, bitter leaf, waterleaf, diabetes mellitus, biochemical parameters.

Methanolic crude leaf extract of Ocimum gratissimum reverses phenylhydrazine-induced anemia in albino wistar rats

2013 ◽  
Vol 1 (1) ◽  
pp. 23
Author(s):  
Nubila Thomas ◽  
UkaejiofoErnest Okem ◽  
NubilaNkoyo Imelda ◽  
IyareEborisiagbon Eghosa ◽  
ChijiokeChioli Pascal ◽  
...  
Keyword(s):  
Wistar Rats ◽  
Leaf Extract ◽  
Ocimum Gratissimum ◽  
Crude Leaf Extract

scholarly journals Safety effect of fractions from methanolic leaf extract of Ocimum gratissimum on reproduction in male wistar rats

2019 ◽  
Vol 6 ◽  
pp. 496-504 ◽  
Author(s):  
Anoka A. Njan ◽  
Solomon O. Olaoye ◽  
Saheed O. Afolabi ◽  
Benjamen C Ejimkonye ◽  
Anthonia Soje ◽  
...  
Keyword(s):  
Wistar Rats ◽  
Leaf Extract ◽  
Ocimum Gratissimum ◽  
Male Wistar Rats ◽  
Safety Effect

Glucose Enzymatic Modulation by Vernonia amygdalina in Streptozotocin- Diabetic Wistar Rats

2016 ◽  
Vol 15 (1) ◽  
pp. 1-14
Author(s):  
Anthony Ojieh ◽  
Anthony Okolo ◽  
Lawrence Ewhre ◽  
Ikenna Njoku ◽  
John Igweh ◽  
...  
Keyword(s):  
Wistar Rats ◽  
Vernonia Amygdalina
Sign in / Sign up

Export Citation Format

Share Document