Ethanolic Extracts Of Vernonia Amygdalina And Ocimum Gratissimum Enhance Testicular Improvement In Diabetic Wistar Rats

10.5580/89d ◽  
2010 ◽  
Vol 8 (2) ◽  
Keyword(s):  
Wistar Rats ◽  
Vernonia Amygdalina ◽  
Ocimum Gratissimum ◽  
Ethanolic Extracts

Ocimum gratissimum enhances insulin sensitivity in male Wistar rats with dexamethasone-induced insulin resistance

2021 ◽  
Author(s):  
Shehu-Tijani Toyin Shittu ◽  
Taye Jemilat Lasisi ◽  
Seyid Alli-Sisse Shittu ◽  
Adeyinka Adeyemi ◽  
Tolulope James Adeoye ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Insulin Sensitivity ◽  
Wistar Rats ◽  
Ocimum Gratissimum ◽  
Male Wistar Rats

Subacute effect of Vernonia amygdalina methanolic crude leaf extract on the hematological profile in albino Wistar rats

2013 ◽  
Vol 1 (1) ◽  
pp. 43
Author(s):  
Thomas Nubila ◽  
NkoyoImelda Nubila ◽  
Ayodele Ukaejiofo ◽  
ElvisNeba Shu ◽  
ChukwubuzorU Okwuosa ◽  
...  
Keyword(s):  
Wistar Rats ◽  
Leaf Extract ◽  
Vernonia Amygdalina ◽  
Hematological Profile ◽  
Crude Leaf Extract

Comparative Antioxidant Activities of Extracts of Vernonia amygdalina and Ocimum gratissimum Leaves

2013 ◽  
Vol 6 (1) ◽  
Author(s):  
Kelly Oriakhi ◽  
Ehigbai Igbuan Oikeh ◽  
Nkeiruka Ezeugwu ◽  
Ogechukwu Anoliefo ◽  
Omorede Aguebor ◽  
...  
Keyword(s):  
Antioxidant Activities ◽  
Vernonia Amygdalina ◽  
Ocimum Gratissimum

GASTRO-PROTECTIVE POTENTIAL OF FLOWERS OF HIBISCUS ROSA-SINENSIS (L.) IN MUCOSAL LESION ON RATS

INDIAN DRUGS ◽  
2019 ◽  
Vol 56 (03) ◽  
pp. 25-31
Author(s):  
K. K Agrawal ◽  
A. Verma ◽  
K Singh ◽  
Keyword(s):  
Wistar Rats ◽  
Gastric Volume ◽  
Control Group ◽  
Phytochemical Screening ◽  
Protective Activity ◽  
Ulcer Index ◽  
Hibiscus Rosa Sinensis ◽  
Pylorus Ligation ◽  
Ethanolic Extracts ◽  
Ulcer Model

study was conducted to evaluate the gastro-protective activity of aqueous (HAE) and ethanolic (HEE) extracts of Hibiscus rosa-sinensis Linn. (Malvaceae) flowers in experimental animals. Aqueous and ethanolic extracts were investigated for pylorus ligation and indomethacin induced ulcer models in albino wistar rats. The pH, gastric volume, ulcer index, ulcer score and free and total acidity were determined by pylorus ligation induced ulcer model and ulcer score, ulcer index and percentage protection were determined by Indomethacin induced ulcer model. Phytochemical screening of aqueous and ethanolic extracts were conducted for and it showed that extracts have alkaloids, glycosides, tannins, flavonoids and mucilage. Both the extracts at dose of 200 and 400mg/kg showed significant (P<0.05) reduction in gastric volume (1.20±0.17, 0.83±0.20, 0.90±0.12, 0.96±0.17) and ulcer index (1.50±0.19, 1.33±0.11, 2.16±0.03, 0.75±0.17, 0.92±0.22, 0.31±0.04, 0.42±0.06, 0.19±0.04) as compared to the control group (1.47±0.15, 3.00±0.21, 1.64±0.13) in both of the models. It can be concluded that both the extracts possess gastro-protective activity that might be due the presence of flavanoids, tannins and/or mucilage.

Biochemical effect of varied mixtures of extracts of Vernonia amygdalina (bitter leaf) and Gnetum africanum (Okazi leaf) on alloxan induced diabetic wistar rats

2021 ◽  
Vol 20 (1) ◽  
pp. 17-30
Author(s):  
M.O. Ifeanacho ◽  
R.B Oshotse
Keyword(s):  
Diabetes Mellitus ◽  
Wistar Rats ◽  
Treated Group ◽  
The Body ◽  
Blood Protein ◽  
Steady Increase ◽  
Vernonia Amygdalina ◽  
Leaf Extracts ◽  
Biochemical Effect ◽  
Total Blood

Diabetes mellitus is prevalent in many countries of the world, affecting all ages both in developing and developed nations. The use of plants as remedies or preventive therapies has increased over the years. The study investigated the biochemical changes caused by  combined leaf extracts of Vernonia amygdalina (bitter leaf) and Gnetum africanum (okazi leaf) on alloxan induced diabetic wistar rats.Aqueous extracts of the leaves were prepared using the conventional method.Forty male wistar rats weighing 150-180g were  grouped into eight (five rats each). Group 1 was the normal control while diabetes was induced using alloxan (160mg/ kg)in groups 2-8.Group 2 received no treatment while groups 3-7 received varied ratios of the extracts at (BI/OK|10:90%), (BI/OK|30:70%),  (BI/OK|50:50%), (BI/OK|70:30%) and (BI/OK|90:10%). Group 8 was the diabetic control treated with the standard diabetic drug (Metformin). The animals were weighed and blood glucose was determined at 7-day intervals. They were sacrificed on the 28th day and blood samples collected for serum protein, serum electrolyte, urea, creatinine, liver enzymes and markers of oxidative stress analyses.  The results showed steady increase in the body weights (g) of the rats with (BI/OK|70:30)% treated group showing the highest increase (175.40±1.28). The fasting blood sugar (mg/dl) showed timedependent reduction in all the treated diabeti groups with (BI/OK|90:10)% having the highest (56.20±1.65) reduction. There was a significant increase (p<0.05) in total blood protein concentration (g/dl) in all the treated groups. The results of this study showed time and ratio dependent effect on the parameters measured. Since the two plants are staple vegetables in some countries, their utilization particularly in appropriate combinations should be encouraged. Key words: Extracts, bitter leaf, waterleaf, diabetes mellitus, biochemical parameters.

Methanolic crude leaf extract of Ocimum gratissimum reverses phenylhydrazine-induced anemia in albino wistar rats

2013 ◽  
Vol 1 (1) ◽  
pp. 23
Author(s):  
Nubila Thomas ◽  
UkaejiofoErnest Okem ◽  
NubilaNkoyo Imelda ◽  
IyareEborisiagbon Eghosa ◽  
ChijiokeChioli Pascal ◽  
...  
Keyword(s):  
Wistar Rats ◽  
Leaf Extract ◽  
Ocimum Gratissimum ◽  
Crude Leaf Extract

scholarly journals Safety effect of fractions from methanolic leaf extract of Ocimum gratissimum on reproduction in male wistar rats

2019 ◽  
Vol 6 ◽  
pp. 496-504 ◽  
Author(s):  
Anoka A. Njan ◽  
Solomon O. Olaoye ◽  
Saheed O. Afolabi ◽  
Benjamen C Ejimkonye ◽  
Anthonia Soje ◽  
...  
Keyword(s):  
Wistar Rats ◽  
Leaf Extract ◽  
Ocimum Gratissimum ◽  
Male Wistar Rats ◽  
Safety Effect

scholarly journals PHYTOCHEMICAL SCREENING AND PURGATIVE ACTIVITY OF ETHANOLIC EXTRACTS OF VERNONIA AMYGDALINA DEL. LEAF

2013 ◽  
Vol 4 (1) ◽  
pp. 46-49 ◽  
Author(s):  
CH Wazis ◽  
SY Timothy ◽  
SG Zakama ◽  
HJ Balla ◽  
ID Maspalma
Keyword(s):  
Phytochemical Screening ◽  
Vernonia Amygdalina ◽  
Ethanolic Extracts
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