scholarly journals Poly (DL-valine) electro-polymerized carbon nanotube paste sensor for determination of antihistamine drug cetirizine

2020 ◽  
Author(s):  
Tigari Girish ◽  
Jamballi G. Manjunatha ◽  
Pemmatte A. Pushpanjali ◽  
Nambudumada S. Prinith ◽  
Doddarasinakere K. Ravishankar ◽  
...  
Keyword(s):  
Carbon Nanotube ◽  
Organic Molecules ◽  
Phosphate Buffer Solution ◽  
Multiwalled Carbon Nanotube ◽  
Buffer Solution ◽  
Solution Ph ◽  
Multiwalled Carbon ◽  
Accumulation Time ◽  
Antihistamine Drug

Poly (DL-valine) modified multiwalled carbon nanotube paste sensor (PVLMCNTPS) was prepared by electro-polymerization route. PVLMCNTPS and bare multiwalled carbon nanotube paste sensor (BMCNTPS) morphologies and sensing properties for cetirizine (CTZ) were confirmed through a field emission scanning electron microscope (FE-SEM) and electrochemical studies, respectively. In contrast to BMCNTPS, PVLMCNTPS surface composite creates an electrocatalytic impact on the oxidation of CTZ. PVLMCNTPS properties were optimized using parameters such as accumulation time, number of polymerization cycles, solution pH, and scan rate. The optimized PVLMCNTPS was applied for the determination of cetirizine in 0.1 M phosphate buffer solution (PBS) of pH 7.0, using cyclic voltammetry (CV). It is shown that PVLMCNTPS provided analytical linearity from 2.0 to 80 µM, with a detection limit of 0.11 µM for CTZ determination. PVLMCNTPS is found highly selective for CTZ in presence of some interfering organic molecules. The stable and selective PVLMCNTPS was applied for CTZ determination in pharmaceutical pills with satisfactory results.

Selective determination of mefenamic acid in the presence of 1000-fold excess paracetamol and caffeine using a multiwalled carbon nanotube–polymer composite electrode

2015 ◽  
Vol 7 (8) ◽  
pp. 3506-3511 ◽  
Author(s):  
K. Rajalakshmi ◽  
S. Abraham John
Keyword(s):  
Carbon Nanotube ◽  
Polymer Composite ◽  
Mefenamic Acid ◽  
Phosphate Buffer Solution ◽  
Multiwalled Carbon Nanotube ◽  
Buffer Solution ◽  
Solution Ph ◽  
Multiwalled Carbon ◽  
Selective Determination

This article describes the selective and sensitive determination of mefenamic acid (MA) using a carboxylated multiwalled carbon nanotube nanostructured conducting polymer composite modified glassy carbon electrode in 0.2 M phosphate buffer solution (pH 7.2).

Non-enzymatic determination of purine nucleotides using a carbon dot modified glassy carbon electrode

2019 ◽  
Vol 11 (30) ◽  
pp. 3866-3873 ◽  
Author(s):  
R. Karthikeyan ◽  
D. James Nelson ◽  
S. Abraham John
Keyword(s):  
Glassy Carbon ◽  
Low Cost ◽  
Phosphate Buffer Solution ◽  
Purine Nucleotides ◽  
Buffer Solution ◽  
Solution Ph ◽  
Carbon Dot ◽  
Enzymatic Determination ◽  
Sensitive Determination

Selective and sensitive determination of one of the purine nucleotides, inosine (INO) using a low cost carbon dot (CD) modified glassy carbon (GC) electrode in 0.2 M phosphate buffer solution (pH 7.2) was demonstrated in this paper.

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