Peripheral Neuromodulation: An Update

Ból ◽  
2017 ◽  
Vol 18 (1) ◽  
pp. 15-27 ◽  
Author(s):  
Teodor Goroszeniuk ◽  
Andrzej Król
Keyword(s):  
Chronic Pain ◽  
Peripheral Nerve ◽  
Nerve Stimulation ◽  
Pain Treatment ◽  
External Stimulation ◽  
Non Invasive ◽  
Technological Advances ◽  
Improved Outcomes ◽  
Chronic Pain Treatment ◽  
And Function

Peripheral nerve stimulation (PNS) is rapidly expanding area of neuromodulation with multiple new indications for chronic pain treatment and function improvement. Since the first percutaneous lead insertion in 1999, the proliferation of nonsurgical techniques with increasingly diverse stimulating targets has resulted that PNS is now a firmly established part of neuromodulation where the majority of new exciting developments are taking place. Non Invasive Peripheral External Stimulation plays an important part in the progress. It can offer a frequently less expensive alternative to the implantable techniques and it can be used outside specialised centers. Technological advances are allowing safer and more efficient uses of PNS with improved outcomes.

scholarly journals Intranasal Administration for Pain: Oxytocin and Other Polypeptides

Pharmaceutics ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 1088
Author(s):  
Vimala N. Bharadwaj ◽  
Alexander Z. Tzabazis ◽  
Michael Klukinov ◽  
Neil A. Manering ◽  
David C. Yeomans
Keyword(s):  
Chronic Pain ◽  
Nervous System ◽  
Pain Treatment ◽  
Peripheral Circulation ◽  
Nervous Systems ◽  
Analgesic Effects ◽  
Non Invasive ◽  
Central Nervous Systems ◽  
Chronic Pain Treatment ◽  
Plastic Changes

Pain, particularly chronic pain, remains one of the most debilitating and difficult-to-treat conditions in medicine. Chronic pain is difficult to treat, in part because it is associated with plastic changes in the peripheral and central nervous systems. Polypeptides are linear organic polymers that are highly selective molecules for neurotransmitter and other nervous system receptors sites, including those associated with pain and analgesia, and so have tremendous potential in pain therapeutics. However, delivery of polypeptides to the nervous system is largely limited due to rapid degradation within the peripheral circulation as well as the blood–brain barrier. One strategy that has been shown to be successful in nervous system deposition of polypeptides is intranasal (IN) delivery. In this narrative review, we discuss the delivery of polypeptides to the peripheral and central nervous systems following IN administration. We briefly discuss the mechanism of delivery via the nasal–cerebral pathway. We review recent studies that demonstrate that polypeptides such as oxytocin, delivered IN, not only reach key pain-modulating regions in the nervous system but, in doing so, evoke significant analgesic effects. IN administration of polypeptides has tremendous potential to provide a non-invasive, rapid and effective method of delivery to the nervous system for chronic pain treatment and management.

Yoga as an Effective Mind--Body Therapy in Chronic-Pain Treatment

2007 ◽  
Author(s):  
Malinda Breda ◽  
Richard Gevirtz ◽  
Melanie A. Greenberg ◽  
James L. Spira
Keyword(s):  
Chronic Pain ◽  
Pain Treatment ◽  
Body Therapy ◽  
Chronic Pain Treatment

scholarly journals Telemedicine for chronic pain treatment during the COVID‐19 pandemic: Do pain intensity and anxiousness correlate with patient acceptance?

Pain Practice ◽  
2021 ◽  
Author(s):  
Michael Alexander Harnik ◽  
Larissa Blättler ◽  
Andreas Limacher ◽  
Florian Reisig ◽  
Martin Grosse Holtforth ◽  
...  
Keyword(s):  
Chronic Pain ◽  
Pain Intensity ◽  
Pain Treatment ◽  
Patient Acceptance ◽  
Chronic Pain Treatment

Problematic Prescription Opioid Use in a Chronic Pain Treatment Facility: The Role of Emotional Processes

2018 ◽  
Vol 54 (3) ◽  
pp. 495-505 ◽  
Author(s):  
Lindsay M. S. Oberleitner ◽  
Mark A. Lumley ◽  
Emily R. Grekin ◽  
Kathryn M. Z. Smith ◽  
Amy M. Loree ◽  
...  
Keyword(s):  
Chronic Pain ◽  
Pain Treatment ◽  
Prescription Opioid ◽  
Opioid Use ◽  
Treatment Facility ◽  
Emotional Processes ◽  
Chronic Pain Treatment ◽  
Prescription Opioid Use

scholarly journals Drop-out from chronic pain treatment programmes: Is randomization justified in biopsychosocial approaches?

2021 ◽  
pp. 0
Author(s):  
A Bicego ◽  
J Monseur ◽  
F Rousseaux ◽  
M Faymonville ◽  
N Malaise ◽  
...  
Keyword(s):  
Chronic Pain ◽  
Pain Treatment ◽  
Drop Out ◽  
Chronic Pain Treatment
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