THE RELATIONSHIP BETWEEN SERUM PROTEIN LEVELS AND HYALINE MEMBRANE DISEASE IN PREMATURE BABIES

1962 ◽  
Vol 2 (24) ◽  
pp. 941-942 ◽  
Author(s):  
Janus M. G. Fraillon ◽  
W. H. Kitchen
Keyword(s):  
Serum Protein ◽  
Hyaline Membrane Disease ◽  
Protein Levels ◽  
Premature Babies ◽  
Hyaline Membrane ◽  
The Relationship

scholarly journals Relationship Between Incidence of Hyaline Membrane Disease and Maternal Hypertension During Pregnancy

2017 ◽  
Vol 38 (3-4) ◽  
pp. 47
Author(s):  
Lasmida Nazir Nuriman ◽  
Dadang Sjarif Hidajat
Keyword(s):  
Distress Syndrome ◽  
Hyaline Membrane Disease ◽  
Cross Sectional Study ◽  
Type I ◽  
Cross Sectional ◽  
Hypertension In Pregnancy ◽  
Hyaline Membrane ◽  
Neonatal Respiratory Distress ◽  
Maternal Hypertension ◽  
The Relationship

There have been controversies over the eiTect of hypertension in pregnancy on the incidence of type I neonatal respiratory distress syndrome or hyaline membrane disease (HMD). We investigated the relationship between the incidence of HMD and maternal hypertension during pregnancy in 91 infants at 34 weeks gestation or less. This retrospective cross sectional study included all live born babies between May 1, 1994 and April 30, 1995 at Dr. Hasan Sadikin General Hospital, Bandung. Maternal hypertension during pregnancy was diagnosed in 38 mothers of91 infants studied. The incidence of HMD (5%) in the maternal hypertension during pregnancy group was significantly lower than the 62% in the normotensive group (p<0.01). There was a negative correlation between the occurence of HMD and hypertension during pregnancy. We conclude that the risk of developing HMD in infants born to hypertensive mothers is significantly lower than those born to normotensive mothers.

▾ Colfosceril palmitate (exosurf) – artificial surfactant for immature lungs

1991 ◽  
Vol 29 (12) ◽  
pp. 46.1-46
Keyword(s):  
Surface Tension ◽  
Respiratory Function ◽  
Distress Syndrome ◽  
Hyaline Membrane Disease ◽  
Lower Surface ◽  
Premature Babies ◽  
Hyaline Membrane ◽  
Lower Surface Tension ◽  
Reducing Substances ◽  
Artificial Surfactant

It has been known for about 30 years that lack of surface tension reducing substances (‘surfactant’) in the lungs of premature infants is largely responsible for the development of hyaline membrane disease or respiratory distress syndrome (RDS). About 50% of premature babies develop RDS, characteristically showing tachypnoea, chest retractions and worsening cyanosis. Many babies die of it or suffer complications. Mechanical ventilation is the main treatment, supporting respiratory function until maturing alveolar lining cells synthesise adequate surfactant. Despite its inherent risks it has proved very successful, but drugs which can lower surface tension in the lungs may improve outcome further.

scholarly journals C-REACTIVE PROTEIN LEVELS - INDICATOR FOR PROGNOSIS OF SPONTANEOUS PRETERM BIRTH IN BULGARIAN WOMEN

2021 ◽  
Vol 2 ◽  
pp. 80-86
Author(s):  
Iliana Koleva-Korkelia ◽  
Yanka Karamalakova
Keyword(s):  
Preterm Birth ◽  
Maternal Age ◽  
Clinical Settings ◽  
Spontaneous Preterm Birth ◽  
Protein Levels ◽  
Reactive Protein ◽  
Premature Babies ◽  
Active Labor ◽  
The Relationship ◽  
Control Study

It is estimated that every year fifteen million premature babies are born worldwide mainly due to spontaneous preterm birth (sPTB). Furthermore, in clinical settings, there still are no reliable and accurate tools to predict preterm labor. Hence, the aim of this pioneering research was to estimate the relationship between the maternal inflammatory indicator and sPTB in a case-control study between 220 South Bulgarian women. The study was conducted at UMBAL, Stara Zagora, Bulgaria (2017-2020) and enrolled a total of 220 women, determined into two groups: 1) TB (n = 110), who were to give birth at term ≥ 37 to ≤ 39 + 6 gestation weeks with active labor at the time of hospitalization; and 2) sPTB (n = 110), women with preterm birth ≤ 32–34 + 6 gestation weeks and declared active labor, who were to give birth within 5-24 hrs. The inflammatory indicators/CRP concentration was quantified in plasma by immunoturbidimetric methods within 2 hrs. in mg/l. The median maternal CRP (8.77 ± 3.91), with cutoff = 4.9 mg/l was identified as optimal inflammation with highest risk of sPTB (sensitivity = 86.6%; specificity = 53.7%, р < 0.0001). Moreover, a cutoff CRP = 4.9 mg/l was found to be most effective in determining maternal age ≤ 19 years, the sensitivity of 68.6%, and positively correlated OR = 8.122 vs. OR = 2.354, with increased total sPTB risk at ≤ 32-34 + 6 weeks, respectively (p < 0.001). In conclusion, increased CRP concentrations and a decreased maternal age were associated with increased risks of sPTB, before ≤ 32-34 + 6 weeks. Minimal inflammation and other factors in combination may also act as sPTB prognosis.

scholarly journals 1402 THE RELATIONSHIP OF ANTENATAL STEROIDS AND PROLONGED RUPTURE OF MEMBRANES (PROM) TO DEVELOPMENT OF HYALINE MEMBRANE DISEASE (HMD)

1981 ◽  
Vol 15 ◽  
pp. 677-677
Author(s):  
Nancy Reed ◽  
Sheryl Silfen ◽  
Ronald Bolognese ◽  
Ronald Wapner ◽  
Frank Bowen ◽  
...  
Keyword(s):  
Hyaline Membrane Disease ◽  
Antenatal Steroids ◽  
Hyaline Membrane ◽  
Relationship Of ◽  
The Relationship

scholarly journals The Relationship Between Hyaline Membrane Disease and Primitive Reflexes in Preterm Newborns with a Corrected Gestational Age of 35 Weeks

2021 ◽  
Vol 4 (7) ◽  
pp. 62-70
Author(s):  
Maria do Céu Pereira Gonçalves ◽  
Giovanna Marcella Cavalcante Carvalho ◽  
Maria Amélia Porto ◽  
Márcia Gonçalves Ribeiro
Keyword(s):  
Gestational Age ◽  
Hyaline Membrane Disease ◽  
Primitive Reflexes ◽  
Hyaline Membrane ◽  
The Relationship ◽  
Preterm Newborns

scholarly journals Frequency of peri-intraventricular hemorrhage and its associated factors in premature newborns

2010 ◽  
Vol 8 (3) ◽  
pp. 315-319 ◽  
Author(s):  
Evelyn Arrais Guzman ◽  
José Ricardo Dias Bertagnon ◽  
Yara Juliano
Keyword(s):  
Mechanical Ventilation ◽  
Blood Transfusion ◽  
Intracranial Hemorrhage ◽  
Intraventricular Hemorrhage ◽  
Associated Factors ◽  
Invasive Mechanical Ventilation ◽  
Hyaline Membrane Disease ◽  
Premature Newborns ◽  
Premature Babies ◽  
Hyaline Membrane

ABSTRACT Objective: To identify the frequency of intracranial hemorrhage and its associated factors in premature newborns. Methods: A cross-sectional study based on a survey of medical records of premature neonates submitted to transfontanellar ultrasound at a hospital located in a southern neighborhood of the city of São Paulo, in 2007. Results: A 50% rate of intracranial hemorrhage was found among premature newborns submitted to transfontanellar ultrasound, and 15.35% among all premature babies born in this hospital in 2007. The statistically significant factors associated to intracranial hemorrhage were gestational age less than 32 weeks, absence of prenatal care, invasive mechanical ventilation, infection, blood transfusion, hyaline membrane disease, hyponatremia and hyperglycemia. Conclusions: The frequency of peri-intraventricular hemorrhage was 50% in patients at risk and 15.35% among all premature babies; the associated factors were gestational age less than 32 weeks, absence of prenatal care, need of invasive mechanical ventilation, infection, blood transfusion, hyaline membrane disease, hyponatremia and hyperglycemia.

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