False‐negative ELISA result for HIV antibody due to an apparent prozone phenomenon

1987 ◽  
Vol 147 (1) ◽  
pp. 42-42 ◽  
Author(s):  
Allison Imrie ◽  
Susan Best ◽  
Ronald Penny ◽  
David A. Cooper
2020 ◽  
Vol 78 (3) ◽  
pp. 265-268
Author(s):  
Filipa Tavares Almeida ◽  
Filomena Azevedo ◽  
Carmen Lisboa

We report a case of early syphilis, presenting as balanitis and papular syphilides in an HIV-infected patient, with a previous history of syphilis infection, which demonstrated a false negative VDRL testing due to a prozone phenomenon. This false negative response results from overwhelming antibody titers, which interfere with the proper formation of the antigen-antibody lattice network, necessary to visualize a positive flocculation test.


Transfusion ◽  
2020 ◽  
Vol 60 (12) ◽  
pp. 3055-3059
Author(s):  
Rachel K. Horton ◽  
Micah D. Zuccarelli ◽  
Laurie L. Wakefield ◽  
Margaret A. DiGuardo ◽  
Manish J. Gandhi ◽  
...  

2019 ◽  
Vol 9 (3) ◽  
pp. 341-343
Author(s):  
Luciane Moraes ◽  
Mara d’Almeida ◽  
Mayra Conde

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