Considerations for the Quality Control of Newly Registered Traditional Chinese Medicine in China: A Review

2019 ◽  
Vol 102 (3) ◽  
pp. 689-694 ◽  
Author(s):  
Jianbo Qu ◽  
Tideng Zhang ◽  
Jiaxing Liu ◽  
Yuanyuan Su ◽  
Hainan Wang
Keyword(s):  
Quality Control ◽  
Control System ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Traditional Medicine ◽  
Quality By Design ◽  
Sustainable Use ◽  
Chinese Traditional Medicine ◽  
Clinical Value ◽  
Use Of Resources

Abstract Background: The quality control of traditional Chinese medicine (TCM) has been essential for the development of TCM industry. In recent years, with the acceleration of TCM modernization, research on the quality control of TCM has reached a higher level. Objective: This article suggested a comprehensive approach to the quality control of TCM and proposed specific requirements for the quality control of newly registered TCM in various phases of development. Method: The views in this article are mainly derived from the laws and regulations of China and the authors’ experiences. Results: It pointed out that the investigation on the quality control of TCM should be led by Chinese traditional medicine theory and guided by the clinical value. Moreover, it should follow the basic principle of “quality by design” and in-process control to establish a quality control system that embodies the characteristics of TCM and accurately reflects the safety, efficacy, and quality consistency. Given that TCM is a natural resource-dependent industry, the quality control of TCM should also focus on the protection and sustainable use of resources. Conclusions: TCM quality control should organically combine Chinese traditional medicine theory with modern science and technology, be guided by clinical value, pay attention to the protection and sustainable use of resources, fully embody the characteristics of quality by design (QbD) and in-process quality control, and gradually establish a quality control system in accordance with the features of Chinese traditional medicine. Highlights: The article has guiding significance for the research and development of newly registered TCM.

scholarly journals Research on the External Communication and Translation Studies of Traditional Chinese Medicine Culture under the Background of "One Belt and One Road "

2019 ◽  
Vol 3 (4) ◽  
pp. 116
Author(s):  
Fangde Zou
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Traditional Medicine ◽  
Translation Studies ◽  
Communication Strategy ◽  
Chinese Traditional Medicine ◽  
Business Card ◽  
External Communication ◽  
The World ◽  
Communication Culture

<p>Culture is the heritage of a country and a bridge of international exchanges. Under the background of "One Belt and One Road", strengthening the communication culture of traditional Chinese medicine to the world can not only achieve the revival of traditional Chinese medicine culture, but also become a brand new cultural business card for China. At the same time, it can make our country occupy a greater international influence. This article will specifically discuss the communication strategy of Chinese traditional medicine culture and its translation studies in the context of "One Belt and One Road ".</p>

scholarly journals Coroless, effective ingredient isolated from traditional Chinese medicine for the prevention and treatment of Covid-19

2021 ◽  
Author(s):  
Nie Leng ◽  
Liang Youdong ◽  
Liang Xinwei
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Traditional Medicine ◽  
Active Ingredient ◽  
Lung Damage ◽  
Chinese Traditional Medicine ◽  
Good Medicine ◽  
Prevention And Treatment

We believe that a good medicine for the prevention and treatment of Covid-19 requires three points: 1. Effectively inhibit the cells from being infected by Covid-19; 2. Quickly repair lung damage; 3. Non-toxic and harmless. Fortunately, from the treasure depot of Chinese traditional medicine, we found Kyllinga brevifolia Rottb, which is sufficient for three points and can be used for prevention, treatment and rehabilitation. Not only that, we have isolated the active ingredient of the Kyllinga brevifolia Rottb, named it Coroless, and verified that Coroless inhibits the Covid-19 from infecting cells through in vitro cell experiments.

scholarly journals A Newly Authenticated Compound from Traditional Chinese Medicine Decoction Induces Melanogenesis in B16-F10 Cells by Increasing Tyrosinase Activity

2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Xiu Juan Xin ◽  
Jiahong Zou ◽  
Tao Zou ◽  
Huoli Shang ◽  
Li Yun Sun
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Cell Number ◽  
Tyrosinase Activity ◽  
Chinese Traditional Medicine ◽  
Inhibition Rate ◽  
Disease Treatment ◽  
Protein Levels ◽  
Stimulation Of

Vitiligo is a kind of skin dysfunction on melanogenesis. The highly prevalent, chronic, and distinctive complexion changes on patients have imposed enormous psychic and economic burden on both individuals and society. Traditional Chinese Medicine (TCM) is a kind of precious source on chronic disease treatment, including skin dysfunctional diseases. In our previous study, a new compound named apigenin-7-butylene glucoside has been authenticated and purified from a prescription of Chinese traditional medicine formula which has been used clinically in vitiligo treatment. The aim of this work is to evaluate the effects of this compound on melanogenesis using melanoma cell B16-F10 in vitro. The results showed that apigenin-7-butylene glucoside had almost no cytotoxicity on B16-F10 cells within a lower dose of 5.0 μg ml-1 and enhanced the melanin level to about 41% and tyrosinase activity to 1.32-fold when compared with controls. The compound showed minor cytotoxicity to B16-F10 cells at the higher concentration of 10 μg ml-1 and 50 μg ml-1, the inhibition rate was 8.4% and 11.8%, and the melanin level and tyrosinase activity showed a decreased trend because of the lower cell number at the higher concentrations. The results indicated that apigenin-7-butylene glucoside was safe to B16-F10 cells within a lower concentration, <5.0 μg ml-1. Incubated with 5.0 ug ml-1of apigenin-7-butylene glucoside for 48 hours, the mRNA and protein levels of Tyr, Trp-1, and Trp-2 genes were all increased except Mitf in B16-F10 cells. The stimulation of apigenin-7-butylene glucoside on melanogenesis of B16-F10 cells through Tyr, Trp-1, and Trp-2 pathway highlighted the potential usage of the compound in vitiligo treatment.

Ayurvedic system a new possible safe and effective way to get rid of this critical nCOVID-19 pandemic situation- A review

2021 ◽  
Vol 07 ◽  
Author(s):  
Sumel Ashique ◽  
Navjot K Sandhu
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Viral Infection ◽  
Traditional Medicine ◽  
Host Cell ◽  
Western Medicine ◽  
Treatment Strategies ◽  
Unani Medicine ◽  
System A ◽  
The World

: The nCOVID-19 virus has become the most threatening infections disease all over the world. From the beginning till today a large number of researches is going on to develop appropriate therapeutics that can prevent and cure this viral infection successfully. But unfortunately, modern western medicine could not find any effective drug having no toxic effects on host cell. TCM (traditional Chinese Medicine) has shown promising effect against nCOVID-19. This TCM contains natural occurring herbal decoctions which showed promising blocking of viral progression in host cell. These ayurvedic formulations containing homeopathic medicine, unani medicine and yoga to challenge the virus. The traditional medicine system is unable to cure properly but it can be a possible preventing strategy to stop this virus pandemicity. This review focuses how the ayurvedic medicines, homeopathic treatment strategies and yoga can impact to prevent the viral infection.

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