scholarly journals A Framework for Executing Protein Sequence Alignment in Cloud Computing Services

2021 ◽  
Author(s):  
Leonardo Reboucas de Carvalho ◽  
Alba Cristina Alves Melo ◽  
Aleteia Araujo

Protein sequence alignment is a task of great relevance in Bioinformatics and the Hirschberg algorithm is widely used for this task. This work proposes a framework for executing sequence alignment with the Hirschberg algorithm in different cloud computing services. In experiments, our framework was used to align HIV-1 protease sequences using different instances of AWS EC2 and different configurations of AWS Lambda functions.The results show that, for this application, there is a tradeoff between the expected execution time and the cost, e.g., in most cases AWS Lambda provides the best runtime, however at a higher USD cost. In this context, it is important to have a framework that helps in deciding which approach is most appropriate.

2015 ◽  
Vol 9 (1and2) ◽  
Author(s):  
Akshay Mehta ◽  
Dr. Sanjay Kumar Dubey

Cloud Computing has emerged very fast in the IT industry. It is based on virtualization technology and provides internet based computing which provides resource pooling, services sharing and on demand access. Its evolution has reduced must of the cost of enterprises as well as of the other industries working with a huge data. With cloud computing emerging at a much faster rate, the situation may soon be changed. But, despite the fact that it provides a number of facilities to the service providers, it has quite a number of issues related to it. The most important issue related to cloud is its security. From the consumer’s perspective, cloud computing security concerns, especially data security and privacy protection issues, remain the primary inhibitor of cloud computing services. Security is the reason that hinders many enterprises to enter into cloud. So this paper gives a detail of the security risks related to cloud and the possible measures which the enterprises need to ensure before entering Cloud Computing.


2014 ◽  
Author(s):  
Seyhan Yazar ◽  
George EC Gooden ◽  
David A Mackey ◽  
Alex Hewitt

A major bottleneck in biological discovery is now emerging at the computational level. Cloud computing offers a dynamic means whereby small and medium-sized laboratories can rapidly adjust their computational capacity. We benchmarked two established cloud computing services, Amazon Web Services Elastic MapReduce (EMR) on Amazon EC2 instances and Google Compute Engine (GCE), using publicly available genomic datasets (E.coli CC102 strain and a Han Chinese male genome) and a standard bioinformatic pipeline on a Hadoop-based platform. Wall-clock time for complete assembly differed by 52.9% (95%CI: 27.5-78.2) for E.coli and 53.5% (95%CI: 34.4-72.6) for human genome, with GCE being more efficient than EMR. The cost of running this experiment on EMR and GCE differed significantly, with the costs on EMR being 257.3% (95%CI: 211.5-303.1) and 173.9% (95%CI: 134.6-213.1) more expensive for E.coli and human assemblies respectively. Thus, GCE was found to outperform EMR both in terms of cost and wall-clock time. Our findings confirm that cloud computing is an efficient and potentially cost-effective alternative for analysis of large genomic datasets. In addition to releasing our cost-effectiveness comparison, we present available ready-to-use scripts for establishing Hadoop instances with Ganglia monitoring on EC2 or GCE.


2014 ◽  
Vol 926-930 ◽  
pp. 3778-3781
Author(s):  
Cong Zheng ◽  
Li Qing Zhou

After the development of decades cloud computing has landed from the cloud and formed a certain scale. Successful examples of the use of cloud computing to reduce operational costs attract many companies. But the comparison for price of cloud computing services and self-built server is not clear and hidden costs of cloud computing services is also not clear. This paper will compare the cost of cloud computing services and self-built server price and analyzed the hidden costs for users as accessing cloud computing decision-making.


2014 ◽  
Vol 3 (2) ◽  
pp. 63-68 ◽  
Author(s):  
Rian Rahmanda Putra ◽  
Wanda Kinasih ◽  
Dana Indra Sensuse

Cloud computing is an innovation that allows the use of IT as a utility based on-demand. Since cloud computing is a new technology, its led to a variety of risks that required an assessment model to assess the organization's readiness to adopt cloud computing. Moreover, by using cloud computing services means organizations or outsourcing involves a third party. Before adopting cloud computing technology, organizations need to consider some of the effects that arise as a result of cloud computing, namely in terms of costs, risks and benefits. To assist organizations to consider the migration of existing IT systems to the cloud, it can be used the cost approach valuation models and risk and benefit. This paper discusses two models of cost-based assessment of risk and benefit modeling and modeling that can be used as a tool to assist organizations in making decisions related to the migration of existing IT systems to the cloud. 


2014 ◽  
Vol 2014 ◽  
pp. 1-12 ◽  
Author(s):  
Daeyong Jung ◽  
JongBeom Lim ◽  
Heonchang Yu ◽  
Taeweon Suh

In cloud computing, users can rent computing resources from service providers according to their demand. Spot instances are unreliable resources provided by cloud computing services at low monetary cost. When users perform tasks on spot instances, there is an inevitable risk of failures that causes the delay of task execution time, resulting in a serious deterioration of quality of service (QoS). To deal with the problem on spot instances, we propose an estimated interval-based checkpointing (EIC) using weighted moving average. Our scheme sets the thresholds of price and execution time based on history. Whenever the actual price and the execution time cross over the thresholds, the system saves the state of spot instances. The Bollinger Bands is adopted to inform the ranges of estimated cost and execution time for user's discretion. The simulation results reveal that, compared to the HBC and REC, the EIC reduces the number of checkpoints and the rollback time. Consequently, the task execution time is decreased with EIC by HBC and REC. The EIC also provides the benefit of the cost reduction by HBC and REC, on average. We also found that the actual cost and execution time fall within the estimated ranges suggested by the Bollinger Bands.


2018 ◽  
Vol 5 (3) ◽  
pp. 305
Author(s):  
Matheus Supriyanto Rumetna

<p class="Abstrak">Bisnis saat ini mulai bersaing secara global untuk dapat memuaskan pelanggan, sehingga perusahaan membutuhkan akses informasi yang cepat dan akurat. Agar dapat mengakses informasi secara cepat, perusahaan perlu membangun infrastruktur Teknologi Informasi dan Komunikasi (TIK) yang memerlukan modal besar, di sisi lain <em>cloud computing</em> hadir sebagai salah satu solusi alternatif. Layanan yang disediakan oleh <em>cloud</em> <em>computing</em>, diantaranya  <em>hardware</em>, infrastruktur, <em>platform</em>, dan aplikasi. <em>Cloud computing</em> sangat bermanfaat, karena dapat mengurangi biaya komputasi, meningkatkan kehandalan serta memberikan peluang yang cukup besar bagi dunia industri TIK. Salah satu perusahaan yang menyediakan jasa layanan <em>cloud computing</em> adalah <em>SalesForce</em>.  Tujuan penelitian ini adalah memberikan kajian tentang manfaat penerapan <em>SalesForce App Cloud</em> bagi perusahaan untuk meningkatkan daya saing usaha yang begitu ketat. Penelitian ini menggunakan metode studi literatur, yang diawali dengan identifikasi masalah sampai analisis dan pembahasan yang berkaitan dengan <em>SalesForce App Cloud,</em> dimana hasil dari penelitian ini adalah <em>SalesForce App Cloud</em> dapat membuat model bisnis lebih fleksibel, lebih cepat mengetahui kebutuhan pasar dan konsumen<em>.</em></p><p><em><br /></em></p><p><em>Abstract</em></p><p><em>Businesses are now beginning to compete globally to be able to satisfy customers, so companies need access to information quickly and accurately. In order to access information quickly, companies need to build an Information and Communication Technology (ICT) infrastructure that requires large capital, on the other hand cloud computing comes as one alternative solution. Services provided by cloud computing, including hardware, infrastructure, platforms and applications. Cloud computing is very useful, because it can reduce the cost of computing, improve reliability and provide a big enough opportunity for the ICT industry. One of the companies that provide cloud computing services is SalesForce. The purpose of this study is to provide a study of the benefits of applying SalesForce App Cloud for the company to improve business competitiveness is so tight. This study uses literature study method, which begins with problem identification until analysis and discussion related to SalesForce App Cloud, where the result of this research is SalesForce App Cloud can make business model more flexible, faster to know the market and consumer needs.</em></p>


Cloud Computing, being a delivery model is swiftly moving ahead by being adopted by small and large organization alike. This new model opens up many research challenges. As, cloud computing services are offered over the Internet on pay-per-use basis, it is very essential to provide fault tolerant services to the users. To ensure high availability, data centers are replicated. The process of replication is costly but in terms reliability it overtakes the cost factors. Vast amount of work has been undertaken in fault tolerance in other computing environments but they cannot be applied directly to the cloud. This gives an opportunity for new, effective solutions. In this paper, we propose policies for delivering fault tolerant services for private cloud computing environment related to virtual machine allocations. The experimental test results and policies derived are described with respect to virtual machine provisioning.


2014 ◽  
Vol 3 ◽  
pp. 94-112
Author(s):  
Angelė Pečeliūnaitė

The article analyses the possibility of how Cloud Computing can be used by libraries to organise activities online. In order to achieve a uniform understanding of the essence of technology SaaS, IaaS, and PaaS, the article discusses the Cloud Computing services, which can be used for the relocation of libraries to the Internet. The improvement of the general activity of libraries in the digital age, the analysis of the international experience in the libraries are examples. Also the article discusses the results of a survey of the Lithuanian scientific community that confirms that 90% of the scientific community is in the interest of getting full access to e-publications online. It is concluded that the decrease in funding for libraries, Cloud Computing can be an economically beneficial step, expanding the library services and improving their quality.


Author(s):  
Shengju Yang

In order to solve the trust problems between users and cloud computing service providers in cloud computing services, the existing trust evaluation technology and access control technology in the cloud computing service are analyzed. And the evaluation index of cloud computing is also analyzed. Users can calculate the relevant indicators of cloud computing service according to their own business goals, and choose the appropriate cloud computing services according to their own trust need. In addition, the reliability assessment method of users based on the service process is proposed. Cloud computing access control system can be used for user credibility evaluation, and it can handle user access requests according to user&#039;s creditability. In the study, a cloud computing service trust evaluation tool is designed, and the modeling and architecture designs of trust evaluation are also given. The effectiveness of the method is verified by experiments on cloud computing service evaluation methods.


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