scholarly journals Diagnostic Value of Multisliced Computed Tomography in Coronary Arteries Atherosclerotic Lesions Detection in the Patients with Coronary Heart Disease - a Comparative Study

Author(s):  
Maryna N. ◽  
Sergey V. ◽  
Natalia N.
Pathologia ◽  
2021 ◽  
Vol 18 (1) ◽  
pp. 39-43
Author(s):  
A. O. Nykonenko ◽  
A. L. Makarenkov ◽  
H. S. Pidluzhnyi ◽  
A. M. Materukhin

Coronary heart disease (CHD) is one of the leading mortality causes. According to the latest guidelines, coronary computed tomography angiography (CCTA) is one of the main non-invasive methods for diagnosis of CHD, which allows for quantification of stenosis severity and the characterization of stenotic lesions. Aim of the study. It is to study the role, diagnostic value and dependence of coronary artery calcification on the degree of stenotic lesion of the coronary arteries and anthropometric parameters in patients with coronary artery disease examined by computed tomography. Materials and methods. According to the purpose of the study, 46 patients were included: 32 (69.6 %) males and 14 (30.4 %) females. The average age of the patients was 59.0 ± 9.8 years, height – 172 ± 9 cm, weight – 85.6 ± 12.9 kg, body mass index (BMI) – 28.6 ± 4.13, body surface area (BSA) – 1.98 ± 0.17 m2. Demographic and clinical variables were analyzed using descriptive statistics. Independent t-tests were conducted between two groups of patients (Agatston index ≥400 and <400), using P < 0.05 as a significant value. Pearson correlation coefficient was employed to determine independent coronary calcium predictors using P < 0.05 as a significant value. Results. According to the results of the age analysis, significant differences were found among both groups of patients (P = 0.02). Notable differences in the number of affected coronary arteries between Groups 1 and 2 with an Agatston index ≥400 and <400 (P < 0.01) were found. During the correlation analysis, a significant moderate positive correlation of the SYNTAX score level with Agatston index (r = 0.69, P < 0.01) was revealed. Conclusions. The degree of coronary arteries calcification with Agatston score ≥400 is an independent predictor of severe coronary heart disease with multivessel lesion of the coronary arteries. The degree of calcification of coronary arteries with Agatston score ≥400 is more common in males. Height, weight, BMI and BSA do not influence the degree of coronary calcification arteries and Agatston score level.


10.12737/7267 ◽  
2014 ◽  
Vol 21 (4) ◽  
pp. 44-48 ◽  
Author(s):  
Вардиков ◽  
D. Vardikov ◽  
Яковлева ◽  
E. Yakovleva

In the Russian Federation, the death rate from cardiovascular disease is more than 56%. The main reason is atherosclerotic coronary artery disease, which leads to the development of coronary heart disease, and myocardial infarction. In the past, the only way to accurately diagnose coronary heart disease was invasive coronary angiography. This technique is deservedly referred to as the &#34;gold standard&#34; due to its high information content. However, coronary angiography is associated with the necessity of hospitalization in a hospital, as well as possible complications inherent in any invasive procedure. Having been in clinical practice multislice computed tomography has opened opportunities for the study of minimally invasive coronary artery status in patients with suspected coronary heart disease. The purpose of this work is to determine the diagnostic possibilities and optimization techniques of multi-detector computed tomographic coronary angiography. The study involved 38 patients with atherosclerotic coronary arteries, anomalies of the coronary arteries, and patients after stenting. The study was performed on a 64-slice “Aquilion 64” and 320-slice “Aquilion One” Toshiba computed tomographic machines. Analysis of the results of multi detector computed tomographic coronary angiography showed high diagnostic information value of this method in the assessment of coronary disease, in determining the type of blood supply distributed by the heart, in the visualization of the peripheral regions of the coronary arteries, and in the assessment of stents. Multi detector com-puted tomographic coronary angiography with 320-slice computed tomographic machine with one volume scan, shows a significant reduction of radiation exposure on the patient.


Kardiologiia ◽  
2019 ◽  
Vol 59 (2) ◽  
pp. 24-31
Author(s):  
H. E. El Manaa ◽  
D. Yu. Shchekochikhin ◽  
M. S. Shabanova ◽  
A. A. Lomonosova ◽  
D. G. Gognieva ◽  
...  

Until today, there are no universally accepted methods for detection of unstable atherosclerotic plaques, even though many recent studies were devoted to this issue. In this article we present modern possibilities of computed tomography in visualization of atherosclerotic coronary lesion, including the detection of unstable lesions, whot in turn, can help in diagnosing subclinical exacerbation of ischemic heart disease and in the stratification of risks of acute coronary events.


2020 ◽  
Vol 92 (4) ◽  
pp. 76-79
Author(s):  
G. N. Soboleva ◽  
S. A. Gaman ◽  
S. K. Ternovoy ◽  
Yu. A. Karpov ◽  
A. A. Minasyan ◽  
...  

The presented clinical observation demonstrates the diagnostic capabilities of cardiac volumetric computed tomography (CT) with a pharmacological test by a vasodilator adenosine triphosphate (ATP) in the simultaneous assessment of coronary anatomy and changes in left ventricular myocardial perfusion (LV) in a patient with painless myocardial ischemia and coronary atherosclerosis. A 68-year-old patient with coronary heart disease (CHD) and atherosclerotic changes in the coronary arteries underwent cardiac volumetric CT in combination with a ATP pharmacological test. The study was performed on a Aquilion ONE 640 Vision Edition computer tomograph (Toshiba, Japan). Assessment of LV myocardial perfusion was carried out in comparison with other clinical, laboratory and instrumental examination methods. The results of clinical and instrumental examination of a patient with a low pre-test probability of coronary heart disease are presented. From the standpoint of modern recommendations on stable coronary heart disease, false-negative results of single-photon emission computed tomography of the heart and stress-echocardiography are discussed. Clinical observation demonstrates the feasibility of diagnosing LV myocardial ischemia by cardiac volumetric CT combined with ATP pharmacological test, confirmed by an invasive determination of the fractional flow reserve. The given clinical example represents the advantage of cardiac volumetric CT, combined with the ATP pharmacological test, as a method for visualizing LV myocardial perfusion in detecting myocardial ischemia.


2013 ◽  
Author(s):  
Elena Malyuta ◽  
Tatiana Raskina ◽  
Olga Barbarash ◽  
Alexandr Kokov

2009 ◽  
Vol 5 (2) ◽  
pp. 15
Author(s):  
Wanda Acampa ◽  
Mario Petretta ◽  
Carmela Nappi ◽  
Alberto Cuocolo ◽  
◽  
...  

Many non-invasive imaging techniques are available for the evaluation of patients with known or suspected coronary heart disease. Among these, computed-tomography-based techniques allow the quantification of coronary atherosclerotic calcium and non-invasive imaging of coronary arteries, whereas nuclear cardiology is the most widely used non-invasive approach for the assessment of myocardial perfusion. The available single-photon-emission computed tomography flow agents are characterised by a cardiac uptake proportional to myocardial blood flow. In addition, different positron emission tomography tracers may be used for the quantitative measurement of myocardial blood flow and coronary flow reserve. Extensive research is being performed in the development of non-invasive coronary angiography and myocardial perfusion imaging using cardiac magnetic resonance. Finally, new multimodality imaging systems have recently been developed bringing together anatomical and functional information. This article provides a description of the available non-invasive imaging techniques in the assessment of coronary anatomy and myocardial perfusion in patients with known or suspected coronary heart disease.


2009 ◽  
Vol 29 (9) ◽  
pp. 1035-1038
Author(s):  
Ning-ning CHEN ◽  
Wei YAO ◽  
Yu-hua ZHAO ◽  
Mei LI ◽  
Yan XI ◽  
...  

2020 ◽  
pp. 5-10
Author(s):  
O. M. Korzh

Among the cardiovascular diseases associated with atherosclerosis, chronic coronary heart disease, including angina, is the most common form. It is the myocardium lesion that develops as a result of an imbalance between the coronary circulation and metabolic needs of heart muscle. The presence of angina symptoms often indicates a pronounced narrowing of one or more coronary arteries, but also occurs in non−obstructive arterial impairment and even in normal coronary arteries. Factors of functional damage to the coronary arteries are spasm, temporary platelet aggregation and intravascular thrombosis. Today there are opportunities not only to use the therapy with proven effectiveness, aimed at reducing the risk of complications, including fatal, but also to treat angina (ischemia), which improves the patient's life quality. The drug protocol includes the ones with a proven positive effect on this disease prognosis, which are mandatory if there are no direct contraindications to use, as well as a large group of antianginal or anti−ischemic drugs. The choice of a particular drug or its combinations with other drugs is carried out in accordance with generally accepted recommendations: taking into account the individual approach, the severity of angina, hemodynamic parameters (heart rate and blood pressure, presence of comorbid conditions). If drug therapy is ineffective, the option of coronary myocardial revascularization (percutaneous coronary angioplasty or coronary artery bypass grafting) is considered. Due to the high mortality and morbidity rates of coronary heart disease worldwide, one of the priorities of practical health care is the prevention of diseases caused by atherosclerosis. Key words: coronary heart disease, angina, family physician, prognosis, drug therapy.


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