scholarly journals Probiotic Yeast: Mode of Action and Its Effects on Ruminant Nutrition

Author(s):  
Shakira Ghazanfar ◽  
Nauman Khalid ◽  
Iftikhar Ahmed ◽  
Muhammad Imran
2021 ◽  
Author(s):  
Shakira Ghazanfar

The gut associated microbiota of animal plays crucial rule in the conversion to accessible nutrients for improve animal health and well-beings. Probiotic yeast (PY) is commonly use to manipulate the gut microbial balance by inhibits the disease-causing microbes and increase the number and function of desirable microbes. PY produce many fermentation metabolites, intercellular effectors, minerals and enzymes that make it an idea nutritive feed supplement for ruminants. The mode of action of the PY is depends on the animal biological inheritance, breed, managemental condition and microbial feeding type. Therefore, PY must formulate using same ecological origin, alone with desirable target; as it would be more compatible with gut ecoysytem and would yield maximum outputs as compare to non-target or foreign probiotic (FP). Therefore, for development of the Indigenous Target Probiotic (ITP), the isolation source must be same ecological region with desirable target like improve animal health and productivity. In the situation of the increase food storage around the world, ITP may provide a useful feed supplements to improve the food production in cost effective manner as compare to FP. Probiotic effectiveness is considered to be population/breed/target specific due to difference in the feed intake, change gut microflora, different food habits and different host-microbial interactions. In this chapter, we will highlight the preparation of the ITP yeast and its mode of action on animal gut microbiota.


Author(s):  
E. A. Elfont ◽  
R. B. Tobin ◽  
D. G. Colton ◽  
M. A. Mehlman

Summary5,-5'-diphenyl-2-thiohydantoin (DPTH) is an effective inhibitor of thyroxine (T4) stimulation of α-glycerophosphate dehydrogenase in rat liver mitochondria. Because this finding indicated a possible tool for future study of the mode of action of thyroxine, the ultrastructural and biochemical effects of DPTH and/or thyroxine on rat liver mere investigated.Rats were fed either standard or DPTH (0.06%) diet for 30 days before T4 (250 ug/kg/day) was injected. Injection of T4 occurred daily for 10 days prior to sacrifice. After removal of the liver and kidneys, part of the tissue was frozen at -50°C for later biocheailcal analyses, while the rest was prefixed in buffered 3.5X glutaraldehyde (390 mOs) and post-fixed in buffered 1Z OsO4 (376 mOs). Tissues were embedded in Araldlte 502 and the sections examined in a Zeiss EM 9S.Hepatocytes from hyperthyroid rats (Fig. 2) demonstrated enlarged and more numerous mitochondria than those of controls (Fig. 1). Glycogen was almost totally absent from the cytoplasm of the T4-treated rats.


Planta Medica ◽  
2007 ◽  
Vol 73 (09) ◽  
Author(s):  
L Moujir ◽  
L de León ◽  
IL Bazzocchi

Diabetes ◽  
1990 ◽  
Vol 39 (10) ◽  
pp. 1243-1250 ◽  
Author(s):  
L. Rossetti ◽  
A. Giaccari ◽  
E. Klein-Robbenhaar ◽  
L. R. Vogel

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