scholarly journals Photodynamic Therapy, a Potential Therapy for Improve Cancer Management

2018 ◽  
Author(s):  
Heidi Abrahamse ◽  
Ivan Sosthene Mfouo Tynga
Keyword(s):  
Photodynamic Therapy ◽  
Cancer Management

Role of bronchoscopic photodynamic therapy in lung cancer management

2004 ◽  
Vol 10 (4) ◽  
pp. 256-260 ◽  
Author(s):  
Keyvan Moghissi
Keyword(s):  
Lung Cancer ◽  
Photodynamic Therapy ◽  
Cancer Management

scholarly journals Immunogenic Cell Death: Can It Be Exploited in PhotoDynamic Therapy for Cancer?

2013 ◽  
Vol 2013 ◽  
pp. 1-18 ◽  
Author(s):  
Elisa Panzarini ◽  
Valentina Inguscio ◽  
Luciana Dini
Keyword(s):  
Cell Death ◽  
Photodynamic Therapy ◽  
Immune System ◽  
Cancer Cells ◽  
Surface Composition ◽  
Immunogenic Cell Death ◽  
Host Immune System ◽  
Tumor Cell Death ◽  
Cancer Management ◽  
Cancer Cell Death

Immunogenic Cell Death (ICD) could represent the keystone in cancer management since tumor cell death induction is crucial as well as the control of cancer cells revival after neoplastic treatment. In this context, the immune system plays a fundamental role. The concept of Damage-Associated Molecular Patterns (DAMPs) has been proposed to explain the immunogenic potential of stressed or dying/dead cells. ICD relies on DAMPs released by or exposed on dying cells. Once released, DAMPs are sensed by immune cells, in particular Dendritic Cells (DCs), acting as activators of Antigen-Presenting Cells (APCs), that in turn stimulate both innate and adaptive immunity. On the other hand, by exposing DAMPs, dying cancer cells change their surface composition, recently indicated as vital for the stimulation of the host immune system and the control of residual ill cells. It is well established that PhotoDynamic Therapy (PDT) for cancer treatment ignites the immune system to elicit a specific antitumor immunity, probably linked to its ability in inducing exposure/release of certain DAMPs, as recently suggested. In the present paper, we discuss the DAMPs associated with PDT and their role in the crossroad between cancer cell death and immunogenicity in PDT.

Photodynamic Therapy

2003 ◽  
Keyword(s):  
Photodynamic Therapy

Construction of a near-infrared responsive upconversion nanoplatform against hypoxic tumors via NO-enhanced photodynamic therapy

Nanoscale ◽  
2020 ◽  
Vol 12 (14) ◽  
pp. 7875-7887 ◽  
Author(s):  
Ying Lan ◽  
Xiaohui Zhu ◽  
Ming Tang ◽  
Yihan Wu ◽  
Jing Zhang ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Near Infrared ◽  
Upconversion Nanoparticles

A near-infrared (NIR) activated theranostic nanoplatform based on upconversion nanoparticles (UCNPs) is developed in order to overcome the hypoxia-associated resistance in photodynamic therapy by photo-release of NO upon NIR illumination.

Porphyrin-functionalized coordination star polymers and their potential applications in photodynamic therapy

2019 ◽  
Vol 10 (45) ◽  
pp. 6116-6121 ◽  
Author(s):  
Tan Ji ◽  
Lei Xia ◽  
Wei Zheng ◽  
Guang-Qiang Yin ◽  
Tao Yue ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Self Assembly ◽  
Star Polymers ◽  
New Family ◽  
Potential Applications

We present a new family of porphyrin-functionalized coordination star polymers prepared through combination of coordination-driven self-assembly and post-assembly polymerization. Their self-assembly behaviour in water and potential for photodynamic therapy were demonstrated.

A nitroreductase-activatable near-infrared theranostic photosensitizer for photodynamic therapy under mild hypoxia

2020 ◽  
Vol 56 (43) ◽  
pp. 5819-5822
Author(s):  
Jing Zheng ◽  
Yongzhuo Liu ◽  
Fengling Song ◽  
Long Jiao ◽  
Yingnan Wu ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Triplet State ◽  
Near Infrared ◽  
Mild Hypoxia

In this study, a near-infrared (NIR) theranostic photosensitizer was developed based on a heptamethine aminocyanine dye with a long-lived triplet state.

Dinuclear phosphorescent rhenium(i) complexes as potential anticancer and photodynamic therapy agents

2020 ◽  
Vol 49 (33) ◽  
pp. 11583-11590 ◽  
Author(s):  
Zheng-Yin Pan ◽  
Dai-Hong Cai ◽  
Liang He
Keyword(s):  
Photodynamic Therapy ◽  
Cell Apoptosis ◽  
Lysosomal Dysfunction ◽  
Intracellular Ros

Two dinuclear organometallic Re(i) complexes increase intracellular ROS levels, causing lysosomal dysfunction and cell apoptosis.

Involvement of CFTR in photodynamic therapy-mediated apoptosis

2010 ◽  
Vol 34 (8) ◽  
pp. S44-S44
Author(s):  
Juan Juan Chen ◽  
Xiao Hua Jiang ◽  
Hsiao Chang Chan
Keyword(s):  
Photodynamic Therapy

Apoptosis is induced by caspase activation and cytochrome c release in photodynamic therapy (PDT) of human hepatoteilular carcinoma cells

2001 ◽  
Vol 120 (5) ◽  
pp. A363-A363
Author(s):  
A OKUMURA ◽  
M HAMBLIN ◽  
T HASAN ◽  
T ISHIKAWA ◽  
S KAKUMU ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Cytochrome C ◽  
Carcinoma Cells ◽  
Caspase Activation ◽  
Cytochrome C Release

Hypericin is an encouraging new photosensitizer for photodynamic therapy of esophageal dysplasia/cancer: Antiproliferative and apoptotic effects

2001 ◽  
Vol 120 (5) ◽  
pp. A443-A443
Author(s):  
M LENZ ◽  
M HOEPFNER ◽  
A THEISS ◽  
B LAMPE ◽  
H KASHTAN ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Esophageal Dysplasia ◽  
Apoptotic Effects
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