scholarly journals Mechanisms of HBO-Induced Vascular Functional Changes in Diabetic Animal Models

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...  
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Gregory S. Hageman ◽  
Paul S. Bernstein

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D. Carvalho ◽  
A. Pereira ◽  
M. Queiroz ◽  
R. Seiça

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pp. 1082 ◽  
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M.A Peterson ◽  
G.C. Gerritsen

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...  

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Vol 120 ◽  
pp. S182-S183
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Hyun Ah Ko ◽  
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Kyung Ae Lee ◽  
Heung Yong Jin ◽  
...  

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2019 ◽  
Vol 11 (3) ◽  
pp. 629 ◽  
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Ling-Shan Tse ◽  
Po-Lin Liao ◽  
Chi-Hao Tsai ◽  
Ching-Hao Li ◽  
Jiunn-Wang Liao ◽  
...  

Hedychium coronarium has a long history of use worldwide as a food and in folk medicine. In this study, we aimed to investigate the effect of an aqueous extract of H. coronarium leaves (HC) on type 2 diabetes mellitus (T2DM). Two types of animal models were used in this study: Streptozotocin (STZ)-induced T2DM (Wistar rats; N = 8) and C57BKSdb/db mice (N = 5). After treatment with HC for 28 days, glucose tolerance improved in both of the diabetic animal models. As significant effects were shown after 14 days of treatment in the STZ-induced T2DM model, we carried out the experiments with it. After 28 days of treatment with HC, the levels of cholesterol, triglyceride, high-density lipoprotein, and low-density lipoprotein were significantly improved in the STZ-induced T2DM model. The lesions degree of islet β-cells was decreased after the HC treatment. Although the insulin level increased moderately, the aldosterone level was significantly decreased in the HC-treated groups, suggesting that aldosterone might play an important role in this effect. In summary, HC is a natural product and it is worth exploring its effect on T2DM.


PLoS ONE ◽  
2012 ◽  
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pp. 276-277
Author(s):  
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E. Ritz ◽  
A. Schoof ◽  
M. Adamczak ◽  
K. Amann

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