scholarly journals Comprehensive Review on Full Bone Regeneration through 3D Printing Approaches

2020 ◽  
Author(s):  
Cristiana Fernandes ◽  
Carla Moura ◽  
Rita M.T. Ascenso ◽  
Sandra Amado ◽  
Nuno Alves ◽  
...  
Keyword(s):  
3D Printing ◽  
Bone Regeneration ◽  
Comprehensive Review

scholarly journals Cobalt-doped bioceramic scaffolds fabricated by 3D printing show enhanced osteogenic and angiogenic properties for bone repair

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Jungang Li ◽  
Chaoqian Zhao ◽  
Chun Liu ◽  
Zhenyu Wang ◽  
Zeming Ling ◽  
...  
Keyword(s):  
Compressive Strength ◽  
3D Printing ◽  
Bone Regeneration ◽  
Doping Concentration ◽  
Artificial Bone ◽  
Bone Defect Repair ◽  
Co Doping ◽  
Defect Repair ◽  
Co Doped

Abstract Background The bone regeneration of artificial bone grafts is still in need of a breakthrough to improve the processes of bone defect repair. Artificial bone grafts should be modified to enable angiogenesis and thus improve osteogenesis. We have previously revealed that crystalline Ca10Li(PO4)7 (CLP) possesses higher compressive strength and better biocompatibility than that of pure beta-tricalcium phosphate (β-TCP). In this work, we explored the possibility of cobalt (Co), known for mimicking hypoxia, doped into CLP to promote osteogenesis and angiogenesis. Methods We designed and manufactured porous scaffolds by doping CLP with various concentrations of Co (0, 0.1, 0.25, 0.5, and 1 mol%) and using 3D printing techniques. The crystal phase, surface morphology, compressive strength, in vitro degradation, and mineralization properties of Co-doped and -undoped CLP scaffolds were investigated. Next, we investigated the biocompatibility and effects of Co-doped and -undoped samples on osteogenic and angiogenic properties in vitro and on bone regeneration in rat cranium defects. Results With increasing Co-doping level, the compressive strength of Co-doped CLP scaffolds decreased in comparison with that of undoped CLP scaffolds, especially when the Co-doping concentration increased to 1 mol%. Co-doped CLP scaffolds possessed excellent degradation properties compared with those of undoped CLP scaffolds. The (0.1, 0.25, 0.5 mol%) Co-doped CLP scaffolds had mineralization properties similar to those of undoped CLP scaffolds, whereas the 1 mol% Co-doped CLP scaffolds shown no mineralization changes. Furthermore, compared with undoped scaffolds, Co-doped CLP scaffolds possessed excellent biocompatibility and prominent osteogenic and angiogenic properties in vitro, notably when the doping concentration was 0.25 mol%. After 8 weeks of implantation, 0.25 mol% Co-doped scaffolds had markedly enhanced bone regeneration at the defect site compared with that of the undoped scaffold. Conclusion In summary, CLP doped with 0.25 mol% Co2+ ions is a prospective method to enhance osteogenic and angiogenic properties, thus promoting bone regeneration in bone defect repair.

Fused filament fabrication: A comprehensive review

2020 ◽  
pp. 089270572097062
Author(s):  
Sudhir Kumar ◽  
Rupinder Singh ◽  
TP Singh ◽  
Ajay Batish
Keyword(s):  
Mechanical Properties ◽  
3D Printing ◽  
Smart Materials ◽  
Low Cost ◽  
Processing Parameters ◽  
View Point ◽  
Fused Filament Fabrication ◽  
Comprehensive Review ◽  
Smart Composites ◽  
Complex Design

Fused filament fabrication (FFF) is one of the low cost additive manufacturing (AM) techniques capable of printing complex design (both with commercial and non-commercial feedstock filaments by using different processing parameters). In this paper a comprehensive review has been prepared on FFF operating capabilities from thermoplastics material’s view point. Various thermoplastic materials and composites available commercially and prepared at laboratory scale have been categorized based upon the reported studies performed (for thermal stability, mechanical properties etc.). It was observed that the nano composite based feed stock filament (prepared at lab scale) have edge over the micro-composites from thermo-mechanical properties view point. Further it has been noticed that the 3D printing is in changing phase and moving towards 4D printing of smart composites and designs. But hitherto little has been reported on printing of smart material with FFF platform. Further studies may be focused on printing of smart materials (both micro and nano composites) with FFF, as the low cost 3D printing solution in different engineering applications.

scholarly journals 3D Printing for Bone Regeneration

2020 ◽  
Vol 18 (5) ◽  
pp. 505-514
Author(s):  
Amit Bandyopadhyay ◽  
Indranath Mitra ◽  
Susmita Bose
Keyword(s):  
3D Printing ◽  
Bone Regeneration

scholarly journals A comprehensive review of recent developments in 3D printing technique for ceramic membrane fabrication for water purification

RSC Advances ◽  
2019 ◽  
Vol 9 (29) ◽  
pp. 16869-16883 ◽  
Author(s):  
Hitesh Dommati ◽  
Saikat Sinha Ray ◽  
Jia-Chang Wang ◽  
Shiao-Shing Chen
Keyword(s):  
Additive Manufacturing ◽  
3D Printing ◽  
Water Purification ◽  
Ceramic Membrane ◽  
Comprehensive Review ◽  
Membrane Fabrication ◽  
Printing Technique ◽  
Recent Developments ◽  
Competitive Prices ◽  
3D Printing Technique

Additive manufacturing (AM), which is also commonly known as 3D printing, provides flexibility in the manufacturing of complex geometric parts at competitive prices and within a low production time.

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