scholarly journals Overview of the Global Prevalence and Diagnostic Criteria of Takotsubo Syndrome

2021 ◽  
Author(s):  
Shogade Taiwo ◽  
Akpabio Akpabio
Keyword(s):  
Sympathetic Innervation ◽  
Apical Ballooning ◽  
Left Ventricular ◽  
Apical Ballooning Syndrome ◽  
Takotsubo Syndrome ◽  
Syndrome Patient ◽  
Cardiac Sympathetic Innervation ◽  
The World ◽  
Uncommon Disease ◽  
As Stress

Takotsubo syndrome (TTS) is an acute and reversible abnormal condition of the heart also known as stress cardiomyopathy, apical ballooning syndrome, or broken heart syndrome. It is an uncommon disease that mostly occurs among Asians though studies have shown its occurrence in other parts of the world. The typical takotsubo syndrome patient has a unique circumferential left ventricular contraction abnormality that extends beyond a coronary artery supply territory and appears to follow the anatomical cardiac sympathetic innervation.

scholarly journals Случай атипичной формы синдрома такоцубо у молодого мужчины

2017 ◽  
pp. 78-85
Keyword(s):  
Myocardial Infarction ◽  
Apical Ballooning ◽  
Left Ventricular ◽  
Apical Ballooning Syndrome ◽  
Takotsubo Syndrome ◽  
Ultrasound Diagnostics

Синдром такоцубо представляет собой транзиторное шаровидное расширение верхушки сердца с дисфункцией в ответ на интенсивный эмоциональный или физический стресс. Эти признаки напоминают инфаркт миокарда, однако при синдроме такоцубо отсутствуют признаки атеротромбоза коронарных артерий, а также их гемодинамически значимого стеноза. Представлены клинический случай атипичного течения синдрома с развитием некротического поражения верхушки левого желудочка, тромбоза его полости и формированием рубцового поля, а также краткий обзор литературы по соответствующей тематике. Ключевые слова: ультразвуковая диагностика, синдром такоцубо, шаровидная деформация верхушки левого желудочка, инфаркт миокарда, тромбоз левого желудочка, ultrasound diagnostics, takotsubo syndrome, apical ballooning syndrome, myocardial infarction, left ventricular thrombosis

scholarly journals Takotsubo syndrome after induction of general anesthesia: three clinical cases

2019 ◽  
Vol 47 (3) ◽  
pp. 236-243
Author(s):  
A. A. Klimov ◽  
M. Yu. Buldakov ◽  
M. V. Gritskevich ◽  
D. A. Zabaluev ◽  
S. A. Kamnev ◽  
...  
Keyword(s):  
Myocardial Ischemia ◽  
General Anesthesia ◽  
Critical Condition ◽  
Coronary Vessels ◽  
Apical Ballooning ◽  
Left Ventricular ◽  
Apical Ballooning Syndrome ◽  
Takotsubo Syndrome ◽  
Ventricular Failure ◽  
Favorable Prognosis

Takotsubo syndrome (stress-induced cardiomyopathy, or apical ballooning syndrome) is a  rare critical condition with approximate incidence of 0.00006% and relatively favorable prognosis. It is characterized by electrocardiographic signs of myocardial ischemia, as well as by severe left ventricular failure with intact coronary vessels. The literature on postoperative development of this disease is scarce. This paper presents three documented cases of takotsubo syndrome with favorable outcomes that developed just after the induction of general anesthesia.

scholarly journals Apical ballooning (Takotsubo) syndrome in the setting of chronic alcohol-induced hyponatremia

2018 ◽  
Vol 5 (4) ◽  
pp. 10
Author(s):  
Yehualashet Bekele Hailemariam ◽  
Olufolahan Carrena ◽  
Derek Eshun ◽  
Henry E. Okafor
Keyword(s):  
Unusual Case ◽  
African American Woman ◽  
Case Reports ◽  
American Woman ◽  
Apical Ballooning ◽  
Left Ventricular ◽  
Apical Ballooning Syndrome ◽  
Chronic Alcohol ◽  
Severe Hyponatremia ◽  
As Stress

 Takotsubo cardiomyopathy is also known as stress induced cardiomyopathy and transient left ventricular apical ballooning syndrome. There have been few case reports where hyponatremia was implicated as a trigger for stress-induced cardiomyopathy. We report the unusual case of a 79-year-old African American woman without any discernible recent stressors who presented atypically with generalized fatigue and was found to have severe hyponatremia (from chronic alcohol use and thiazide diuretics) and significantly elevated Troponin. Her echocardiogram and cardiac catheterization revealed typical features of apical ballooning syndrome.

scholarly journals Rare recurrence of apical ballooning (takotsubo) syndrome in an elderly man

2018 ◽  
pp. bcr-2017-222451
Author(s):  
Rosalyn Adigun ◽  
Samantha Morley ◽  
Abhiram Prasad
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Left Ventricular Systolic Dysfunction ◽  
Systolic Dysfunction ◽  
Obstructive Coronary Artery Disease ◽  
Apical Ballooning ◽  
Left Ventricular ◽  
Major Surgery ◽  
Apical Ballooning Syndrome ◽  
Elderly Male

Apical ballooning syndrome (ABS) is an under recognised clinical entity characterised by acute reversible left ventricular systolic dysfunction that mimics acute myocardial infarction in the absence of obstructive coronary artery disease; typically occurring in the setting of profound stress.1 ABS disproportionately affects older women and recurrences are infrequent. We, hereby, describe a rare phenomenon of recurrent ABS in an elderly male patient, 10 years apart, presenting with the same left ventricular morphological appearance following non-cardiac surgeries. The case illustrates the importance of considering ABS in the differential diagnosis of perioperative acute myocardial infarction in older men undergoing major surgery.

Out-of-hospital cardiac arrest caused by transient left ventricular apical ballooning syndrome

2008 ◽  
Vol 128 (1) ◽  
pp. e31-e33 ◽  
Author(s):  
Riccardo Raddino ◽  
Claudio Pedrinazzi ◽  
Gregoriana Zanini ◽  
Debora Robba ◽  
Cinzia Portera ◽  
...  
Keyword(s):  
Cardiac Arrest ◽  
Apical Ballooning ◽  
Left Ventricular ◽  
Apical Ballooning Syndrome ◽  
Hospital Cardiac Arrest

scholarly journals Recurrent Takotsubo Cardiomyopathy Related to Recurrent Thyrotoxicosis

2016 ◽  
Vol 43 (2) ◽  
pp. 152-155 ◽  
Author(s):  
Keval Patel ◽  
George T. Griffing ◽  
Paul J. Hauptman ◽  
Joshua M. Stolker
Keyword(s):  
Left Ventricular Function ◽  
Ventricular Function ◽  
Takotsubo Cardiomyopathy ◽  
Obstructive Coronary Artery Disease ◽  
Apical Ballooning ◽  
Left Ventricular ◽  
Apical Ballooning Syndrome ◽  
Wall Motion Abnormalities ◽  
Artery Disease

Takotsubo cardiomyopathy, or transient left ventricular apical ballooning syndrome, is characterized by acute left ventricular dysfunction caused by transient wall-motion abnormalities of the left ventricular apex and mid ventricle in the absence of obstructive coronary artery disease. Recurrent episodes are rare but have been reported, and several cases of takotsubo cardiomyopathy have been described in the presence of hyperthyroidism. We report the case of a 55-year-old woman who had recurrent takotsubo cardiomyopathy, documented by repeat coronary angiography and evaluations of left ventricular function, in the presence of recurrent hyperthyroidism related to Graves disease. After both episodes, the patient's left ventricular function returned to normal when her thyroid function normalized. These findings suggest a possible role of thyroid-hormone excess in the pathophysiology of some patients who have takotsubo cardiomyopathy.

P2624Association between renal dysfunction and cardiac sympathetic innervation in patients with heart failure

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
F Marsico ◽  
S Paolillo ◽  
P Gargiulo ◽  
I Esposito ◽  
S Dell'aversana ◽  
...  
Keyword(s):  
Heart Failure ◽  
Renal Function ◽  
Renal Dysfunction ◽  
Sympathetic Activity ◽  
Nyha Class ◽  
Sympathetic Innervation ◽  
Venous Blood ◽  
Left Ventricular ◽  
Washout Rate ◽  
Cardiac Sympathetic Innervation

Abstract Introduction In heart failure (HF) a strict interaction exists between heart and kidney. Previous studies reported a significant impact of sympathetic overdrive, that causes beta-adrenoceptor desensitization, in both renal and heart failure progression. It can be hypothesized that renal failure might be associated with impaired sympathetic activity assessed directly at the myocardial level in patients affected by HF. Purpose Aim of the present observational study was to assess the relationship between renal dysfunction and cardiac sympathetic innervation in HF patients with mildly and severely reduced ejection fraction (HFrEF and HFmEF). Methods Two-hundred and sixty-three patients (84% males; 66±10.8 years) with mild-to-severe HF (EF 31±6.8%) underwent iodine-123 meta-iodobenzylguanidine (123I-MIBG) myocardial scintigraphy to assess sympathetic innervation, evaluating early and late heart to mediastinum (H/M) ratios and washout rate. All patients also underwent clinical evaluation and venous blood sample collection for the assessment of serum creatinine and consequently the estimation of glomerular filtration rate (eGFR) by EPI formula. Results A direct correlation was found between EPI-eGFR and late H/M (r=0,215; p<0.001) (figure 1), with an inverse correlation between NYHA class and late H/M (r=0,152; p=0.013), and a direct correlation between left ventricular EF and late H/M (r=0,348; p<0.001). These results were not confirmed for early H/M, nor washout rate. Dividing the population in reduced eGFR and normal eGFR (cut-off ≤60 ml/min/1,73m2), a statistical significant reduction of late H/M value was found in patients with reduced eGFR (late H/M = 1,49±0,21) compared with patients with preserved eGFR (late H/M = 1,56±0,26) (p=0.020). In a multivariate model, adjusting eGFR for NYHA class and left ventricular EF, reduced eGFR and left ventricular EF remained significant predictors of reduced late H/M (p=0.006 and p<0.001, respectively). Figure 1. linear regression curve Conclusions Patients with impaired renal function and HF show impaired cardiac sympathetic activity compared to HF patients with preserved renal function, and reduced eGFR estimated by EPI formula is a significant predictor of reduced late H/M evaluated by 123I-MIBG. Thus, in future studies, the combination of these two parameters might provide addictive prognostic information in HF patients.

scholarly journals Takotsubo syndrome induced by brachytherapy in a patient with endocervical adenocarcinoma

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Aline Cristini Vieira ◽  
Mauricio Fernando Silva Almeida Ribeiro ◽  
Julianne Lima ◽  
Jacob Sessim Filho ◽  
Heloisa de Andrade Carvalho ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Heart Function ◽  
Locally Advanced ◽  
Physical Stress ◽  
Left Ventricular ◽  
Cardiac Biomarkers ◽  
Public Health Issue ◽  
Apical Ballooning Syndrome ◽  
Takotsubo Syndrome ◽  
Low Middle Income Countries

Abstract Background Takotsubo syndrome (TTS), also known as stress cardiomyopathy, apical ballooning syndrome and broken heart syndrome, is characterized by acute-onset chest pain, electrocardiographic (ECG) abnormalities and reversible left ventricular (LV) disfunction in the absence of a culprit obstructive lesion in the coronary arteries; therefore, myocardial infarction is the most important differential diagnosis. Usually induced by emotional/physical stress, its treatment consists in hemodynamic support until complete and spontaneous recovery occurs, which is generally achieved within a few days to weeks. Cervical malignancies are an important public health issue in low/middle-income countries and, in the setting of locally advanced disease, concurrent chemoradiation followed by brachytherapy is considered the standard treatment, harboring curative potential. Case report We report a case of a 38-year-old woman who underwent concurrent chemoradiotherapy and developed cardiopulmonary arrest in ventricular fibrillation during a brachytherapy session. Complementary tests disclosed altered ECG and cardiac biomarkers, no evidence of coronary artery obstruction, as well as LV disfunction consistent with TTS on echocardiogram and cardiac MRI. After few days of supportive therapy, complete recovery of heart function was observed. Conclusions Especially for cancer patients, who usually experience intense emotional/physical stress intrinsically associated with their diagnosis and aggressive treatments, considering TTS as a differential diagnosis is warranted. Intracavitary brachytherapy procedure may represent a trigger for TTS.

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