scholarly journals Cardiorespiratory Parameters in Intermittent Positive Pressure Ventilation Versus Spontaneous Ventilation in Under One-Year-Old Pediatrics: A Randomized Trial

2021 ◽  
Vol 31 (3) ◽  
Author(s):  
Ali Zare ◽  
Alireza Ghanbari ◽  
Arman Nasiri ◽  
Behrang Nooralishahi ◽  
Hamid Zaferani Arani

Background: Cardiac catheterization is a useful method for determining the anatomy and pressure in cardiac vessels and chambers. The use of anesthesia methods with minimal hemodynamic and respiratory effects can increase diagnostic accuracy. Objectives: Since there are a few exclusive pediatric angiography centers, scarce studies have been done in this area. Accordingly, this study determined the effects of intermittent positive pressure ventilation (IPPV) versus spontaneous ventilation on cardiorespiratory parameters in less than one-year-old pediatric patients undergoing angiography with general anesthesia. Methods: In this interventional study that was performed as a double-blind, randomized clinical trial, 60 children younger than one year were enrolled. The pulmonary, renal, hepatic, and metabolic background diseases, previous cardiac and thoracic surgery, requiring over two ketamine doses, and receiving sedative or anti-convulsant therapeutics were excluded. The patients were randomly assigned to two groups, including IPPV and spontaneous ventilation. Their vital signs were also recorded before and after anesthesia induction and needling, as well as during measurements of pulmonary parameters and systemic blood pressure. All measurements were done by a single operator using the same device for each variable. Results: It was seen that SPO2, as well as PCO2 after anesthesia had significant alterations among the study variables. Nausea and vomiting, pain, and agitation were not different across the groups (P-value > 0.05). Conclusions: In this study, we found that IPPV and spontaneous ventilation have the same effects on respiration. Both techniques can be used in children with different cardiovascular catheterization conditions to increase accuracy and reduce alterations in cardiopulmonary parameters.

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Saul Chemonges

This study aimed to determine the effect of intermittent positive pressure ventilation (IPPV) on the depth of inhalation anaesthesia in parrots. Anaesthesia was induced with 3.0% isoflurane in six Sulphur-crested Cockatoos (Cacatua galerita galerita) and maintained using either 1.5% or 3.0% during spontaneous ventilation (SV) or IPPV at 6 (IPPV-6) or 12 (IPPV-12) breaths per minute. The time taken for the appearance of somatic reflexes and the return of SV after IPPV was recorded. During recovery, the body jerk, beak, eye, and shivering reflexes appeared after 126 ± 27 s, 133 ± 26 s, 165 ± 34 s, and 165 ± 44 s, respectively. All cockatoos developed apnoea after IPPV-12 and only some did after IPPV-6. Return of SV after IPPV-12 was delayed compared to IPPV-6. Recovery times after the SV runs were significantly different between 1.5% and 3.0% isoflurane anaesthesia. Similarly, after IPPV, the recovery times were significantly different between 1.5% and 3.0% isoflurane anaesthesia. Recovery times after 3.0% inhaled isoflurane were longer than those of 1.5% inhaled isoflurane. In conclusion, cockatoos recovering from isoflurane anaesthesia are likely to exhibit body jerk, beak, eye, and shivering reflexes in that order. IPPV increases the depth of anaesthesia in a rate and dose-related manner and prolongs recovery.


Author(s):  
Bayane Sabsabi ◽  
Ava Harrison ◽  
Laura Banfield ◽  
Amit Mukerji

Objective The study aimed to systematically review and analyze the impact of nasal intermittent positive pressure ventilation (NIPPV) versus continuous positive airway pressure (CPAP) on apnea of prematurity (AOP) in preterm neonates. Study Design In this systematic review and meta-analysis, experimental studies enrolling preterm infants comparing NIPPV (synchronized, nonsynchronized, and bi-level) and CPAP (all types) were searched in multiple databases and screened for the assessment of AOP. Primary outcome was AOP frequency per hour (as defined by authors of included studies). Results Out of 4,980 articles identified, 18 studies were included with eight studies contributing to the primary outcome. All studies had a high risk of bias, with significant heterogeneity in definition and measurement of AOP. There was no difference in AOPs per hour between NIPPV versus CPAP (weighted mean difference = −0.19; 95% confidence interval [CI]: −0.76 to 0.37; eight studies, 456 patients). However, in a post hoc analysis evaluating the presence of any AOP (over varying time periods), the pooled odds ratio (OR) was lower with NIPPV (OR: 0.46; 95% CI: 0.32–0.67; 10 studies, 872 patients). Conclusion NIPPV was not associated with decrease in AOP frequency, although demonstrated lower odds of developing any AOP. However, definite recommendations cannot be made based on the quality of the published evidence. Key Points


1995 ◽  
Vol 79 (1) ◽  
pp. 176-185 ◽  
Author(s):  
V. Jounieaux ◽  
G. Aubert ◽  
M. Dury ◽  
P. Delguste ◽  
D. O. Rodenstein

We have recently observed obstructive apneas during nasal intermittent positive-pressure ventilation (nIPPV) and suggested that they were due to hypocapnia-induced glottic closure. To confirm this hypothesis, we studied seven healthy subjects and submitted them to nIPPV while their glottis was continuously monitored through a fiber-optic bronchoscope. During wakefulness, we measured breath by breath the widest inspiratory angle formed by the vocal cords at the anterior commissure along with several other indexes. Mechanical ventilation was progressively increased up to 30 l/min. In the absence of diaphragmatic activity, increases in delivered minute ventilation resulted in progressive narrowing of the vocal cords, with an increase in inspiratory resistance and a progressive reduction in the percentage of the delivered tidal volume effectively reaching the lungs. Adding CO2 to the inspired gas led to partial widening of the glottis in two of three subjects. Moreover, activation of the diaphragmatic muscle was always associated with a significant inspiratory abduction of the vocal cords. Sporadically, complete adduction of the vocal cords was directly responsible for obstructive laryngeal apneas and cyclic changes in the glottic aperture resulted in waxing and waning of tidal volume. We conclude that in awake humans passive ventilation with nIPPV results in vocal cord adduction that depends partly on hypocapnia, but our results suggest that other factors may also influence glottic width.


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