scholarly journals Correlation between Left Atrial Appendage and Right Atrial Appendage Velocities in Different Pathologies and Normal Subjects

2020 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Mohaddeseh Behjati ◽  
Saman Rostambeigi ◽  
Azin Alizadehasl

2012 ◽  
Vol 20 (1) ◽  
pp. 37
Author(s):  
Bu-Kyung Kim ◽  
Jung-Ho Heo ◽  
Jae-Woo Lee ◽  
Hyun-Soo Kim ◽  
Byung-Joo Choi ◽  
...  

2011 ◽  
Vol 301 (3) ◽  
pp. H964-H974 ◽  
Author(s):  
Joshua M. Lader ◽  
Carolina Vasquez ◽  
Li Bao ◽  
Karen Maass ◽  
Jiaxiang Qu ◽  
...  

Hypertension is associated with the development of atrial fibrillation; however, the electrophysiological consequences of this condition remain poorly understood. ATP-sensitive K+ (KATP) channels, which contribute to ventricular arrhythmias, are also expressed in the atria. We hypothesized that salt-induced elevated blood pressure (BP) leads to atrial KATP channel activation and increased arrhythmia inducibility. Elevated BP was induced in mice with a high-salt diet (HS) for 4 wk. High-resolution optical mapping was used to measure atrial arrhythmia inducibility, effective refractory period (ERP), and action potential duration at 90% repolarization (APD90). Excised patch clamping was performed to quantify KATP channel properties and density. KATP channel protein expression was also evaluated. Atrial arrhythmia inducibility was 22% higher in HS hearts compared with control hearts. ERP and APD90 were significantly shorter in the right atrial appendage and left atrial appendage of HS hearts compared with control hearts. Perfusion with 1 μM glibenclamide or 300 μM tolbutamide significantly decreased arrhythmia inducibility and prolonged APD90 in HS hearts compared with untreated HS hearts. KATP channel density was 156% higher in myocytes isolated from HS animals compared with control animals. Sulfonylurea receptor 1 protein expression was increased in the left atrial appendage and right atrial appendage of HS animals (415% and 372% of NS animals, respectively). In conclusion, KATP channel activation provides a mechanistic link between salt-induced elevated BP and increased atrial arrhythmia inducibility. The findings of this study have important implications for the treatment and prevention of atrial arrhythmias in the setting of hypertensive heart disease and may lead to new therapeutic approaches.


2020 ◽  
Vol 11 (5) ◽  
pp. 641-642
Author(s):  
Nitin Madan ◽  
Anitha Parthiban ◽  
Richard Lorber

Left juxtaposition of the right atrial appendage (RAA) is a rare congenital cardiac malformation, where both atrial appendages are located leftward of the great arteries. Despite well-described echocardiographic markers, this diagnosis remains challenging to establish, especially for the novice imager. We describe the apical view sign in three patients with juxtaposed RAA. We noted that the normal left atrial appendage was visualized from the apical four-chamber or equivalent coronal view at the level of the atrioventricular valves.


2008 ◽  
Vol 16 (2) ◽  
pp. 218-220 ◽  
Author(s):  
Orhan Ozer ◽  
Ibrahim Sari ◽  
Vedat Davutoglu

Atrial fibrillation (AF) is the most common clinically encountered arrhythmia in adults. Because it is associated with an increased risk of atrial thrombus formation and embolism, medical and/or electrical cardioversion is the preferred treatment method in the majority of clinics. Thrombus formation in the setting of AF most commonly occurs in the left atrial appendage (LAA), left atrium (LA), right atrial appendage (RAA), and right atrium in decreasing frequency. In routine transesophageal echocardiographic evaluation for AF, examination is generally limited to LA and LAA. Although relatively rare when compared with the left side, RAA thrombus has also the potential of embolism and should be screened. A case of RAA thrombus in which the LA and LAA were spared is described. The authors aimed to underline the importance of this rare but potentially dangerous complication of AF.


2016 ◽  
Vol 01 (02) ◽  
pp. 022-024
Author(s):  
Oruganti Harish ◽  
Mantha Srinivas ◽  

AbstractObjective : To see the Left atrial appendage size (width and length) in ischemic cerebrovascular accident (CVA) patients.Design and method: Transesophageal echocardiography (TEE) was done in ischemic CVA patients after initial stabilization. We compared width length ratio(WLR) calculated from the average of width and length of LAA observed in earlier study by John P et al as controls. We chose this autopsy study as controls, as it is not possible to have TEE data in normal subjects.Results : Study group includes 143 patients (F:M::37:106) and control group was 400 subjects (F:M::200:200) from the previous study. The mean ± std of width and length of LAA in females and males in study group were 1.99±0.67, 2.397±0.58 and 2.19±0.73, 2.49±0.66 respectively. In females, WLR is more (0.83 ± 0.37) in study group than in control group (0.66±0.26) which is statistically significant (z=4.06, P < 0.000001). So also for males (study group: control group :: 0.88 ±0.39 : 0.71±0.28) which is also statistically significant (z=7.03, P < 0.000001). So, broad and short LAA could determine the formation and dislodgement of thrombus resulting in embolic stroke in both sexes.In conclusion, higher the width length ratio of left atrial appendage greater chances of embolic stoke.


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