scholarly journals Relationship between expression of triggering receptor-1 on myeloid cells in intestinal tissue and intestinal barrier dysfunction in severe acute pancreatitis

2011 ◽  
Vol 2 (3) ◽  
pp. 216 ◽  
Author(s):  
Kai Yin ◽  
Sheng-chun Dang ◽  
Jian-xin Zhang
Keyword(s):  
Acute Pancreatitis ◽  
Severe Acute Pancreatitis ◽  
Myeloid Cells ◽  
Intestinal Barrier ◽  
Barrier Dysfunction ◽  
Intestinal Tissue ◽  
Intestinal Barrier Dysfunction

scholarly journals Probiotics Prevent Intestinal Barrier Dysfunction in Acute Pancreatitis in Rats via Induction of Ileal Mucosal Glutathione Biosynthesis

PLoS ONE ◽  
2009 ◽  
Vol 4 (2) ◽  
pp. e4512 ◽  
Author(s):  
Femke Lutgendorff ◽  
Rian M. Nijmeijer ◽  
Per A. Sandström ◽  
Lena M. Trulsson ◽  
Karl-Eric Magnusson ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Intestinal Barrier ◽  
Barrier Dysfunction ◽  
Intestinal Barrier Dysfunction ◽  
Glutathione Biosynthesis

W1769 Pretreatment But Not Treatment with Probiotics Abolishes Mouse Intestinal Barrier Dysfunction in Acute Pancreatitis

2008 ◽  
Vol 134 (4) ◽  
pp. A-711-A-712
Author(s):  
Jakub Rychter ◽  
Paul L. van Minnen ◽  
Andre Verheem ◽  
Harro M. Timmerman ◽  
Ger T. Rijkers ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Intestinal Barrier ◽  
Barrier Dysfunction ◽  
Intestinal Barrier Dysfunction

scholarly journals TREM-1 Promotes Pancreatitis-Associated Intestinal Barrier Dysfunction

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Shengchun Dang ◽  
Yao Shen ◽  
Kai Yin ◽  
Jianxin Zhang
Keyword(s):  
Innate Immunity ◽  
Animal Model ◽  
Acute Pancreatitis ◽  
Intestinal Barrier ◽  
Related Protein ◽  
Barrier Dysfunction ◽  
Intestinal Barrier Dysfunction ◽  
Risk Of Mortality ◽  
Membrane Bound

Severe acute pancreatitis (SAP) can cause intestinal barrier dysfunction (IBD), which significantly increases the disease severity and risk of mortality. We hypothesized that the innate immunity- and inflammatory-related protein-triggering receptor expressed on myeloid cells-1 (TREM-1) contributes to this complication of SAP. Thus, we investigated the effect of TREM-1 pathway modulation on a rat model of pancreatitis-associated IBD. In this study we sought to clarify the role of TREM-1 in the pathophysiology of intestinal barrier dysfunction in SAP. Specifically, we evaluated levels of serum TREM-1 and membrane-bound TREM-1 in the intestine and pancreas from an animal model of experimentally induced SAP. TREM-1 pathway blockade by LP17 treatment may suppress pancreatitis-associated IBD and ameliorate the damage to the intestinal mucosa barrier.

Tu1915 Intestinal Barrier Dysfunction in Ageing Animals With Acute Pancreatitis: Increased Intestinal Inflammation?

2015 ◽  
Vol 148 (4) ◽  
pp. S-1190 ◽  
Author(s):  
Marcel C. Machado ◽  
Fabiano Pinheiro da Silva ◽  
Debora G. Cunha ◽  
Denise F. Barbeiro ◽  
Ana Maria M. Coelho ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Intestinal Inflammation ◽  
Intestinal Barrier ◽  
Barrier Dysfunction ◽  
Intestinal Barrier Dysfunction
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